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Guidelines for the Early Clinical and Public Health Management of ...

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<strong>Guidelines</strong> <strong>for</strong> <strong>the</strong> <strong>Early</strong> <strong>Clinical</strong> <strong>and</strong> <strong>Public</strong> <strong>Health</strong> <strong>Management</strong> <strong>of</strong> Bacterial Meningitis (including Meningococcal Disease)<br />

7.5 The public health response<br />

The public health response should be implemented as soon as possible, <strong>and</strong> includes <strong>the</strong> following actions:<br />

• Identification <strong>of</strong> close contacts.<br />

(The designated medical <strong>of</strong>ficers <strong>of</strong> health (MOH) under Infectious Disease Regulations 34 have <strong>the</strong> authority<br />

<strong>and</strong> obligation to “make such enquiries <strong>and</strong> take such steps as are necessary or desirable <strong>for</strong> investigating<br />

<strong>the</strong> nature <strong>and</strong> source <strong>of</strong> such infection, <strong>for</strong> preventing <strong>the</strong> spread <strong>of</strong> such infection <strong>and</strong> <strong>for</strong> removing<br />

conditions favourable to such infection”. Under <strong>the</strong>se same regulations, “a person who refuses to comply<br />

with a requirement or direction given or a request <strong>for</strong> in<strong>for</strong>mation made in pursuance <strong>of</strong> any <strong>of</strong> <strong>the</strong> provisions<br />

<strong>of</strong> <strong>the</strong>se Regulations shall be guilty <strong>of</strong> a contravention <strong>of</strong> <strong>the</strong>se Regulations”).<br />

• Arranging appropriate chemoprophylaxis to those identified as requiring prophylaxis.<br />

• Provision <strong>of</strong> appropriate in<strong>for</strong>mation.<br />

7.5.1 Dissemination <strong>of</strong> in<strong>for</strong>mation<br />

Following a case <strong>of</strong> meningococcal disease, it is important to give out in<strong>for</strong>mation because early diagnosis <strong>and</strong><br />

treatment should improve outcome. There is a small but real risk <strong>of</strong> fur<strong>the</strong>r linked cases. 46 Vigilance <strong>for</strong> signs <strong>and</strong><br />

symptoms among contacts is important especially in <strong>the</strong> immediate high risk period (one week) after onset <strong>of</strong><br />

symptoms in a case. Accurate <strong>and</strong> timely in<strong>for</strong>mation should help limit <strong>the</strong> spread <strong>of</strong> false rumours <strong>and</strong> anxiety <strong>and</strong><br />

to some extent allay public concern.<br />

In<strong>for</strong>mation should be sufficient to ensure awareness <strong>of</strong> <strong>the</strong> situation whiles preserving patient confidentiality.<br />

The family <strong>of</strong> a case should be in<strong>for</strong>med that in<strong>for</strong>mation will be distributed as appropriate. Leaflets or o<strong>the</strong>r printed<br />

material about meningococcal disease should be widely available <strong>and</strong> quickly distributed after reporting <strong>of</strong> a<br />

confirmed or clinical case. Examples <strong>of</strong> in<strong>for</strong>mation sheets can be found in <strong>the</strong> Appendix <strong>of</strong> <strong>the</strong>se guidelines.<br />

In<strong>for</strong>mation to those given chemoprophylaxis should include:<br />

• Symptoms <strong>and</strong> signs <strong>of</strong> <strong>the</strong> disease <strong>and</strong> <strong>the</strong> need to seek urgent medical advice should <strong>the</strong>y become unwell<br />

• Chemoprophylaxis does not exclude <strong>the</strong> possibility, although small, <strong>of</strong> a person developing meningococcal<br />

disease<br />

• There is no need <strong>for</strong> an asymptomatic person who is taking chemoprophylaxis to be ‘quarantined’ in any way<br />

Recipients should be given this in<strong>for</strong>mation at <strong>the</strong> time <strong>of</strong> receiving chemoprophylaxis. This in<strong>for</strong>mation is covered in<br />

<strong>the</strong> example sheets at <strong>the</strong> back <strong>of</strong> <strong>the</strong> document (see Appendix <strong>for</strong> examples).<br />

Consider <strong>the</strong> need to in<strong>for</strong>m o<strong>the</strong>r HSE colleagues, GPs <strong>and</strong> GP out-<strong>of</strong>-hours services about <strong>the</strong> case <strong>and</strong> what public<br />

health actions have been taken or are required.<br />

When a case occurs in a childcare facility <strong>the</strong> manager should be in<strong>for</strong>med. The in<strong>for</strong>mation should be sufficient<br />

to ensure that o<strong>the</strong>r parents are aware <strong>of</strong> <strong>the</strong> situation whilst preserving <strong>the</strong> confidentiality <strong>of</strong> <strong>the</strong> patient.<br />

Arrangements should be made to provide in<strong>for</strong>mation <strong>for</strong> all <strong>the</strong> parents <strong>and</strong>, if indicated, chemoprophylaxis <strong>for</strong><br />

those identified as close contacts.<br />

When a case occurs in a school or college <strong>the</strong> principal/head should be in<strong>for</strong>med. Arrangements should be made to<br />

provide in<strong>for</strong>mation <strong>for</strong> o<strong>the</strong>r parents/students. The in<strong>for</strong>mation should be sufficient to ensure that parents/students<br />

are aware <strong>of</strong> <strong>the</strong> situation whilst preserving <strong>the</strong> confidentiality <strong>of</strong> <strong>the</strong> patient.<br />

If a suspected case occurs in a childcare or educational facility <strong>and</strong> public health action is not immediately indicated<br />

(e.g. a case considered that diagnoses o<strong>the</strong>r than meningococcal disease are at least as likely) it may still be<br />

advisable to discuss <strong>the</strong> situation with <strong>the</strong> manager/head at an early stage. The manager/head will <strong>the</strong>n be in a<br />

good position to respond immediately to parental concerns.<br />

7.5.2 Vaccines<br />

Meningococcal serogroup C conjugate vaccine (MenC)<br />

Meningococcal serogroup C conjugate vaccine (MenC) was introduced into <strong>the</strong> Irish childhood immunisation<br />

programme in October 2000 <strong>and</strong> a catch-up programme was provided to all children <strong>and</strong> young adults up to <strong>the</strong><br />

age <strong>of</strong> 23 years. The vaccine confers high levels <strong>of</strong> serum bactericidal antibody <strong>and</strong> induces immunological memory<br />

in individuals from <strong>the</strong> age <strong>of</strong> two months. 60 Preliminary estimates <strong>of</strong> vaccine efficacy suggest that <strong>the</strong> vaccine is 88-<br />

96% effective against invasive meningococcal disease due to serogroup C infection. Protection declines over time<br />

especially when given under 1 year <strong>of</strong> age. 61<br />

-64-

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