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Pyrexia - PACT - ESICM

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Task 1. Assessing and measuring fever in ICU<br />

Approach to<br />

the febrile<br />

patient in the<br />

ICU<br />

Dimopoulos G, Falagas ME. Approach to the febrile patient in the ICU. Infect Dis Clin<br />

North Am 2009; 23(3): 471–484. PMID 19665078<br />

This figure, and a number of the figures used below, are slides in the<br />

recommended <strong>ESICM</strong> Flash Conference: George Dimopoulos. Late fever in an<br />

ICU patient, Barcelona, 2010.<br />

Fever – notable features and measurement<br />

Prior to assessment, you will wish to confirm the presence of fever and<br />

determine its severity. Response to fever varies with age. Elderly patients are<br />

unable to regulate their body temperature to the same degree as young adults,<br />

making them susceptible to extremes of temperature – older patients with<br />

serious infections have a substantial prevalence of apyrexia (20% to 30%) and a<br />

lower febrile response than younger patients. A lack of fever may contribute to<br />

lower resistance to infection, delayed recovery, and suboptimal outcome while<br />

lower febrile responses to infection are associated with a higher mortality rate<br />

and poorer prognosis. In children between the ages of six months and six years,<br />

febrile convulsions may occur.<br />

Core temperature measurement is, of course, the gold standard and several<br />

methods may be used in the ICU, involving the placement of a thermistor or<br />

similar device in the pulmonary (or femoral) artery, the bladder or the<br />

oesophagus. In practice, however, surrogate site (rectal, oral or axillary)<br />

temperature measurement is often used (Table below).<br />

[6]

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