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Scheele Award Scheele Committee - Apotekarsocieteten

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isolated and characterized several organic acids (lactic-, pyrogallic-,<br />

gallic-, oxalic-, citric-, tartaric-, malic-, mucic- and uric<br />

acid). He invented improved processes for preparing calomel,<br />

phosphorus and ether, and, without realizing it, he touched<br />

upon the principle of photography.<br />

In honour of the world-renowned<br />

Swedish chemist and pharmacist Carl<br />

Wilhelm <strong>Scheele</strong> the Swedish Academy<br />

of Pharmaceutical Sciences has since<br />

the year of 1961 bestowed the <strong>Scheele</strong><br />

<strong>Award</strong> to prominent scientists in<br />

the field of drug research or related<br />

disciplines.<br />

Jan van der Greef<br />

The <strong>Scheele</strong> Pharmacy in Köping, Sweden<br />

The <strong>Scheele</strong> <strong>Award</strong> 2005<br />

The dependence of the development of chemistry on pharmacy<br />

is brilliantly illustrated through the career of Carl Wilhelm<br />

<strong>Scheele</strong>. A native of Strahllsund in northern Germany (in<br />

those days a Swedish province), <strong>Scheele</strong> moved to Sweden at<br />

a young age. In the laboratory of his out-of-the-way town of<br />

Köping, <strong>Scheele</strong> eventually finalized many of the experiments<br />

he had begun during his pharmaceutical apprenticeship and<br />

clerkships in Gothenburg, Malmoe, Stockholm and Uppsala.<br />

The amazing number, quality and variety of experiments<br />

performed by <strong>Scheele</strong> in his short life (1742-1786) clearly<br />

show that his devotion to the laboratory exceeded his devotion<br />

to his pharmacy shop. His discoveries were many and<br />

varied. First of all, <strong>Scheele</strong> should be given proper credit for<br />

the discovery of oxygen in the year 1773. Due to a delay in<br />

the publication of his findings and to the relative isolation in<br />

which <strong>Scheele</strong> lived and worked, the discovery of deflogisticated<br />

air has often been accredited to Joseph Priestly. Apart<br />

from oxygen, <strong>Scheele</strong> discovered seven other elements; barium,<br />

chlorine, fluoride, manganese, molybdenum, nitrogen<br />

and tungsten. <strong>Scheele</strong> discovered and characterized ammonia<br />

and a number of inorganic acids (arsenic, tungstic-, molybdic-,<br />

hydrofluoric- and nitrosulfonic acid). He also discovered,<br />

<strong>Scheele</strong>’s Unanswered Letter<br />

In this letter <strong>Scheele</strong>, the apothecary in Uppsala, thanks the French<br />

scientist Lavoisier for his book and tries to establish a collaboration<br />

for the study of oxygen with the well-equipped Lavoisier. Apparently<br />

Lavoisier never replied, even though <strong>Scheele</strong> had gone to the trouble<br />

to have a friend help him render the letter from German into French.<br />

Some say this is evidence that <strong>Scheele</strong> was the first to discover the<br />

existence of Oxygen.<br />

Equipment developed by <strong>Scheele</strong> for the preparation of oxygen.<br />

The <strong>Scheele</strong> <strong>Award</strong> 2005 has been bestowed upon Professor<br />

Jan van der Greef of the TNO Institute, the Netherlands, for<br />

his visionary contributions in the field of pharmaceutical and<br />

biomedical analysis. His research covers the introduction and<br />

use of advanced techniques such as NMR and mass spectrometry<br />

for quantitative purposes, especially in combination<br />

with the development of multivariate statistical tools. In addition,<br />

Prof. van der Greef recently demonstrated the importance<br />

and role of analytical sciences in systems biology.<br />

Prof. van der Greef is a pioneer in the area of drug quantization<br />

and drug metabolism. Technology developments have<br />

played a vital role in a number of clinical studies conducted<br />

under his leadership. As a result of the pharmaceutical scientific<br />

activities of Prof. van der Greef, several small enterprises<br />

have been formed (Kiadis and BG Medicine). These successful<br />

biotech- and biomedical companies have developed expertise<br />

in specific steps of the drug development process. He has also<br />

been able to balance an active academic leadership as professor<br />

at the University of Leiden, the Netherlands, with his role<br />

as a leader of the TNO institute.<br />

The <strong>Scheele</strong> Symposium, this year with the theme Systems<br />

Biology, will be held at the Biotech Forum in Stockholm on<br />

the 11th of October. It is divided into two parts and includes<br />

many eminent and recognized speakers in the field.

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