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Prediction of individual antibiotic dose in the clinic - WorldPharma ...

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Piperacill<strong>in</strong>/tazobactam given every 6 h or<br />

with 4 h <strong>in</strong>fusion every 8 h<br />

Lodise CID 2007<br />

• Patients with APACHE score > 17<br />

14-days mortality was significant lower <strong>in</strong><br />

<strong>the</strong> group <strong>of</strong> patients that had received 4 h<br />

<strong>in</strong>fusion<br />

12.2 vs 31.6% (p=0.04)

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