Prediction of individual antibiotic dose in the clinic - WorldPharma ...

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Piperacillin/tazobactam Spectrum MIC-values (native)mg/L • ß-hemolytiska streptokocker gr. A 0.016-0.064 • pneumokocker 0.008-0.032 • H. influenzae 0.016-0.064 • S. aureus 0.25-1 • E. faecalis 1-8 • E. coli 0.5-4 • Klebsiella 0.5-8 • P. mirabilis 0.125-1 • Enterobacter spp. 0.5-8 • P. aeruginosa 1-8 • Acinetobacter 1-16 • B. fragilis 0.5-8
MIC MIC-gränser breakpoints • Pharmacological breakpoints: 8/16 • Speciesrelated breakpoints : Enterobacteriacae 8/16 Pseudomonas 16/16
Page 1: Prediction of individual antibiotic
Page 4 and 5: Concentration dependent killing of
Page 6 and 7: Intergration between pharmacokineti
Page 8 and 9: ß-lactam antibiotics • Efficacy
Page 10 and 11: Quiolones och aminoglycosids • Ef
Page 12 and 13: Depends on • How long has the pat
Page 14 and 15: Relationship Between Time Above MIC
Page 16 and 17: www.eucast.org
Page 18 and 19: MIC MIC-gränser breakpoints • Ph
Page 20 and 21: Dosing T>MIC; MIC=0.03 mg/L T>MIC;
Page 24 and 25: Pharmacokinetics of cloxacillin •
Page 28 and 29: S I R
Page 30: Dosing T>MIC; MIC=1 mg/L T>MIC; MIC
Page 33 and 34: MIC MIC-gränser breakpoints • Ph
Page 35: Dosing T>MIC; MIC=0.03 mg/ L T>MIC;

Prediction of individual antibiotic dose in the clinic - WorldPharma ...

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