Liberation from Mechanical Ventilation E. Wesley Ely, MD, MPH

More documents

Recommendations

Info

<strong>Liberation</strong> decrease exposure
Sedation Protocols: The Evidence Trial RCT Outcome(s) Improved by Protocol Brook et al.1999 Yes Ventilator days, ICU LOS Kress et al. 2000 Yes Ventilator days, ICU LOS Brattebo et al. 2002 No Ventilator days de Lemos et al. 2005 Yes Ventilator days, ICU LOS De Jonghe et al. 2005 No Ventilator days, time to awaken Chanques et al. 2006 No Ventilator days, pain/agitation, infection Quenot et al. 2007 No Ventilator days, extubation success, VAP Arias-Rivera et al. 2008 No Extubation success Bucknall et al. 2008 Yes None Girard et al. 2008 Yes Ventilator days, hospital LOS, survival Robinson et al. 2008 No Ventilator days, hospital LOS Tobar et al. 2008 Yes Oversedation rate
Page 1 and 2: Wake Up and Breathe: Liberation and
Page 3 and 4: Pain Lack of sleep Difficulty breat
Page 5 and 6: % Neurocognitive Sequelae No ICU Re
Page 7: Liberation & Animation Ely EW, et a
Page 11 and 12: Patients Receiving Mechanical Venti
Page 13 and 14: ABC Trial - Objectives • To deter
Page 15 and 16: Spontaneous Breathing Trial
Page 17 and 18: Daily Dose of Opiates 6000 Usual Ca
Page 19 and 20: Patients Discharged from the ICU (%
Page 21 and 22: Patients Alive (%) 100 80 One-Year
Page 23 and 24: Long-Term Cognitive Outcomes Time o
Page 25 and 26: Randomized Trial of Light vs. Deep
Page 27 and 28: Outcome Primary Endpoint 4 weeks af
Page 29 and 30: Animation early mobilization
Page 31 and 32: Schweickert et al, Lancet 2009;373:
Page 33 and 34: Animation = Less Delirium Variable
Page 36 and 37: The BRAIN ICU Project - Overview -

Liberation from Mechanical Ventilation E. Wesley Ely, MD, MPH

You also want an ePaper? Increase the reach of your titles

Delete template?

Save as template?