Bruker AXS Overview of Biological SAXS Webinar 20120614

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The Reciprocity: Size – Scattering Angle Small particles Wide SAXS range Large particles Narrow SAXS range 8
angle (degrees) Why is SAXS Special • The angular resolution needs to be much better for SAXS than for XRD – • only ~ 6° ROI for two decades in real space 50 40 WAXS 30 Molecular Lattice Unit cell dimensions symmetry 20 10 0 Nano-Envelope Size / Shape SAXS 10 100 1000 distance (A) 9
Page 1 and 2: An Overview of Biological SAXS: Ins
Page 3 and 4: Pioneers of (Bio-)SAXS Otto Kratky
Page 5 and 6: SAXS - X-Ray Scattering in Transmis
Page 7: Typical Time Scales -6 -4 -2 0 2 lo
Page 11 and 12: Where Can SAXS Help in Biology •
Page 13 and 14: Proteomics - Structural Biology Q:
Page 15 and 16: Biomaterials: Hair, Skin, Bone, Woo
Page 17 and 18: log I SAXS Information on Protein S
Page 19 and 20: Protein Folding - Kratky Plot The a
Page 21 and 22: Pair Distance Distribution Function
Page 23 and 24: Solution Structure Modeling Graphic
Page 25 and 26: In 1971: 10 min/point 25
Page 27 and 28: Speed of SAXS Dilute protein soluti
Page 29 and 30: Conclusions • Protein SAXS does n
Page 31 and 32: Liposomes and Lipoplexes a Rich Fie
Page 33 and 34: Drug Liposome Interaction DSC-trace
Page 35 and 36: 0.1 0.2 0.3 0.4 0.1 0.2 0.3 0.4 0.1
Page 37 and 38: ‚Hybrid Analysis‘ Getting the B
Page 39 and 40: The Need for Lab-SAXS: Just-In-Time
Page 41 and 42: SAXS and NMR Enhanced Accuracy NMR
Page 43 and 44: SAXS and NMR R G ------------------
Page 45 and 46: Thin Film Structure by GISAXS Diffr
Page 47 and 48: Functionalized Peptide - Lipid Film
Page 49 and 50: The MICRO Revolution 49
Page 51 and 52: Kratky vs Pin-Hole Collimation MICR
Page 53 and 54: MICROpix - Sample Cells • Liquid
Page 55 and 56: Combining SWAX S3-MICROcaliX & Calo
Page 57 and 58: Micro-Calorimeter Specifications
Page 59 and 60:
Silver Behenate SAXS-DSC with Bruke
Page 61 and 62:
Cocoa Butter Polymorphism - SWAXS/D
Page 63:
Innovation with Integrity © Copyri
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Bruker AXS Overview of Biological SAXS Webinar 20120614

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