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Epidemiology of Disease

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Factors Influencing <strong>Disease</strong> Transmission<br />

Agent<br />

<strong>Disease</strong><br />

Environment<br />

•Dose<br />

• Housing (ventilation, sanitation)<br />

• Environmental hardiness<br />

• Environmental conditions<br />

• Virulence (microbial) RISK (temperature, humidity, airflow,<br />

• Infectivity (microbial)<br />

precipitation)<br />

• Toxicity (poisons)<br />

• Stocking density<br />

• Antigenic stability<br />

• Nutrition (protein, energy and<br />

• Survival<br />

macromineral and micromineral<br />

Host<br />

• Age<br />

adequacy)<br />

• Innate resistance (e.g. gastric barrier, mucocilliary action)<br />

• Previous exposure/ active immune status<br />

• Passive immune status (neonates)<br />

• Vaccination status and response<br />

• Production status (e.g., lactating vs. non-lactating)

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