Single Vial Docetaxel Injection - ION Solutions

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Table 6 - Adverse Reactions Regardless of Relationship to Treatment in Chemotherapy-Naïve Advanced Non-Small Cell Lung Cancer Patients Receiving Docetaxel in Combination with Cisplatin Adverse Reaction Neutropenia Any Grade 3/4 Docetaxel 75 mg/m 2 + Cisplatin 75 mg/m 2 n=406 % Vinorelbine 25 mg/m 2 + Cisplatin 100 mg/m 2 n=396 % 91 90 74 78 Febrile Neutropenia 5 5 Thrombocytopenia Any Grade 3/4 Anemia Any Grade 3/4 Infection Any Grade 3/4 Fever in absence of infection Any Grade 3/4 Hypersensitivity Reaction* Any Grade 3/4 Fluid Retention** Any All severe or life-threatening events Pleural effusion Any All severe or life-threatening events Peripheral edema Any All severe or life-threatening events Weight gain Any All severe or life-threatening events Neurosensory Any Grade 3/4 Neuromotor Any Grade 3/4 15 3 89 7 35 8 33
Adverse Reaction Skin Any Grade 3/4 Nausea Any Grade 3/4 Vomiting Any Grade 3/4 Diarrhea Any Grade 3/4 Anorexia** Any All severe or life-threatening events Stomatitis Any Grade 3/4 Alopecia Any Grade 3 Asthenia** Any All severe or life-threatening events Nail Disorder** Any All severe events Myalgia** Any All severe events *Replaces NCI Term "Allergy" **COSTART term and grading system Docetaxel 75 mg/m 2 + Cisplatin 75 mg/m 2 n=406 % 16
Page 1 and 2: Frequently Asked Questions Hospira
Page 5 and 6: HIGHLIGHTS OF PRESCRIBING INFORMATI
Page 7 and 8: FULL PRESCRIBING INFORMATION WARNIN
Page 9 and 10: Injection administration in order t
Page 11 and 12: Please follow the preparation instr
Page 13 and 14: discontinuation of the Docetaxel In
Page 15 and 16: Docetaxel 100 mg/m 2 : Adverse drug
Page 17 and 18: Hematologic Reactions Reversible ma
Page 19 and 20: Table 2 - Hematologic Adverse React
Page 21 and 22: 60 mg/m 2 vs. 6.9% and 16.5% for pa
Page 23 and 24: Gastrointestinal Reactions In addit
Page 25: Docetaxel 75 mg/m 2 n=176 % Best Su
Page 29 and 30: Table 7 - Clinically Important Trea
Page 31 and 32: In vivo studies showed that the exp
Page 33 and 34: observed in mice at 48 mg/kg (about
Page 35 and 36: however, includes a substantial ran
Page 37 and 38: Table 8 - Efficacy of Docetaxel in
Page 39 and 40: doxorubicin 50 mg/m 2 and cyclophos
Page 41 and 42: infections, and treatment-related m
Page 43 and 44: Combination Therapy with Docetaxel
Page 45 and 46: Figure 5 - TAX327 Survival K-M Curv
Page 47 and 48: If your white blood cells are too l
Page 49 and 50: General information about Docetaxel

Single Vial Docetaxel Injection - ION Solutions

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