Curriculum Vitae - College of Pharmacy - Nova Southeastern ...

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A. LYMPEROPOULOS-CV responsiveness to adrenergic stimulation. Am. J. Physiol. Heart Circ. Physiol. 293: H1596- H1603 (2007) 37) Flordellis, C., Papathanasopoulos, P., Lymperopoulos, A., Matsoukas, J., Paris, H. Emerging therapeutic approaches multi-targeting receptor tyrosine kinases and g protein-coupled receptors in cardiovascular disease. Cardiovasc. Hematol. Agents Med. Chem. 5: 133-145 (2007). Review 38) Karkoulias, G., Mastrogianni, O., Ilias, I., Lymperopoulos, A., Taraviras, S., Tsopanoglou, N., Sitaras, N., Flordellis, C.S. Alpha 2-adrenergic receptors decrease DNA replication and cell proliferation and induce neurite outgrowth in transfected rat pheochromocytoma cells. Ann. N. Y. Acad. Sci. 1088: 335-345 (2006) 39) Lymperopoulos, A., Karkoulias, G., Koch, W.J., Flordellis, C.S. alpha(2)-Adrenergic receptor subtype-specific activation of NF-kappaB in PC12 cells. Neurosci. Lett. 402: 210-215 (2006) 40) Manolis, A.S., Patsouras, N., Ilias, I., Constantakopoulos, J., Pyriohou, A., Lymperopoulos, A., Spathas, D.H., Flordellis C.S. Lack of association between alpha2B-adrenergic receptor polymorphism and risk of restenosis following coronary angioplasty and stent implantation--preliminary report. Clin. Chem. Lab. Med. 44: 807-812 (2006) 41) Karkoulias, G., Mastrogianni, O., Lymperopoulos, A., Paris, H., Flordellis, C. alpha(2)- Adrenergic receptors activate MAPK and Akt through a pathway involving arachidonic acid metabolism by cytochrome P450-dependent epoxygenase, matrix metalloproteinase activation and subtype-specific transactivation of EGFR. Cell. Signal. 18: 729-739 (2006) 42) Flordellis, C., Paris, H., Karabinis, A., Lymperopoulos, A. Pharmacogenomics of adrenoceptors. Pharmacogenomics 5: 803-817 (2004). Review 43) Taraviras, S., Olli-Lahdesmaki, T., Lymperopoulos, A., Charitonidou, D., Mavroidis, E., Kallio, J., Scheinin, M., Flordellis, C. α 2 -adrenergic receptor subtypes regulate neuronal differentiation of transfected PC12 cells through MAPK activation. Eur. J. Cell Biol. 81: 363- 374 (2002) 44) Schaak, S., Cayla, C., Lymperopoulos, A., Flordellis, C., Cussac, D., Denis, C., and Paris, H. Transcriptional down-regulation of the human α 2C -adrenergic receptor by cAMP. Mol. Pharmacol. 58: 821-827 (2000) Textbooks-Book Chapters: 1) Lymperopoulos, A., and French, F. Pharmacogenomics of Heart Failure. In Qing Yan (Editor): Pharmacogenomics in Drug Discovery and Development, 2 nd Edition, Methods in Molecular Biology-Springer Protocols, UK: Humana Press, 2014, pp. 245-257 (2014) 10
A. LYMPEROPOULOS-CV 2) Lymperopoulos, A., and Bathgate, A. Arrestins in the Cardiovascular System. In Louis M. Luttrell, editors: The Molecular Biology of Arrestins, Vol. 118, PMBTS, UK: Academic Press, 2013, pp. 297-334 (2013) 3) Lymperopoulos, A., Rengo, G., Gao, E., Ebert, S.N., Dorn, G.W., and Koch, W.J. Adrenal-specific G protein-coupled receptor kinase (GRK)-2 deficiency reduces circulating catecholamine levels and improves cardiac function after myocardial infarction. In L. Eiden (Editor): Catecholamine Research in the 21st Century: Abstracts and Graphical Abstracts, 10th International Catecholamine Symposium 2012, Oxford, UK: Elsevier, 2013, p. 224, Theme H: Catecholamines in the Periphery (2013) 4) Lymperopoulos, A., and Koch, W.J. Autonomic Pharmacology. In Pharmacology and Therapeutics: Principles to Practice (1st edn) (Waldman, S.A. and Terzic, A., eds), Part 1: Principles, Section 3: Systems pharmacology, Chapter 9: Autonomic Pharmacology, pp. 115-139, Saunders/Elsevier, ISBN: 978- 1-4160-3291-5, Language: English (2009) 5) Lymperopoulos, A., Pairas, G., Scheinin, M., and Flordellis, C. Decreased GRKmediated Phosphorylation of a Polymorphic α 2B -adrenergic Receptor in PC12 Cells. 3rd HELLENIC FORUM ON BIOACTIVE PEPTIDES, P.A. Cordopatis, E. Manessi-Zoupa and G. Pairas (Eds.), TYPORAMA, pp. 259-273 (2003) 6) Manolis, A.S., Lymperopoulos, A., Bouga, E.A., Scheinin, M., and Flordellis, C.S. Significance of G-protein –coupled receptor polymorphisms: The case of α 2 - adrenergic receptor. Drug Discovery and Design: Medical Aspects, J.Matscoukas and T. Mavromoustakos (Eds.), IOS Press, Vol. 55: 299-304 (2002) Published Abstracts: 1) Lymperopoulos, A., Rengo, G., Koch, W.J. Regulation of aldosterone levels by adrenal βarrestin-1 as a new molecular target in heart failure. J. Heart Disease, Vol. 8, Nr. 1, July 2011, p. 117, Oral Presentation Abstract #467, 16 th World Congress on Heart Disease, Vancouver, BC, Canada, 23-26 July 2011 2) Lymperopoulos, A., Rengo, G., Magafa, V., Cordopatis, P., Koch, W.J. Biased Agonism/Antagonism of Sartans and Angiotensin II Analogs for Angiotensin II Type 1 Receptor-Induced, β-Arrestin-Dependent Aldosterone Production in Heart Failure. Circ. Suppl. II, Vol. 122, Oral Presentation Abstract #10263, 2010 AHA Scientific Sessions, Chicago, IL, USA, 13-17 November 2010 3) Jasmin, J.F., Rengo, G., Lymperopoulos, A., Gupta, R., Eaton, G., Quann, K., Gonzales, D., Mercier, I., Koch, W.J., Lisanti, M.P. Caveolin-1 Deficiency Exacerbates Cardiac Dysfunction and Reduces Survival in Mice with Myocardial Infarction. Circ. Suppl. II, Vol. 122, Poster Presentation Abstract #14567, 2010 AHA Scientific Sessions, Chicago, IL, USA, 13-17 November 2010 11
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