Curriculum Vitae - College of Pharmacy - Nova Southeastern ...

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A. LYMPEROPOULOS-CV 19) Lymperopoulos, A., Funakoshi, H., Shapiro, M., Cohn, H.I., Eckhart, A.D., Angelotti, T., Koch, W.J. Adrenal G-protein coupled Receptor Kinase (GRK) 2 activity is a potential novel bio-marker of sympathetic outflow in chronic heart failure, Circ. Suppl. II, Vol. 114, No 18, II-36, Abstract #318, October 31, 2006 20) Lymperopoulos, A., Pleger. S.T., Eckhart, A.D., Koch, W.J. Adrenal G-protein Coupled Receptor Kinase 2 Up-regulation Mediates Catecholaminergic Overstimulation of the Failing Heart. Circ. Suppl. II, Vol. 112, No 17, II-80, Abstract #468, October 25, 2005 21) Lymperopoulos, A. The impact of GPCR polymorphisms on medicinal chemistry. Lecture L31, 5th INTERNATIONAL CONFERENCE IN “MEDICINAL CHEMISTRY: DRUG DISCOVERY AND DESIGN”, Patras, Greece (2004) 22) Lymperopoulos, A., Pairas, G., Scheinin, M., and Flordellis, C. Impaired agonist-promoted desensitization of a polymorphic α 2B -adrenergic receptor in PC12 cells. European Journal of Drug Metabolism and Pharmacokinetics, Vol. 28, Nr. 1: Page 17 (2003) 23) Lymperopoulos, A., Pandeli, E., Karkoulias, G., Mastroyianni, O., Pyriohou, A., and Flordellis, C. Epinephrine Induces the Activation of the Transcription Factors AP-1 and NF-κB in PC12 Cells Transfected with α 2 -Adrenergic Receptors. Review of Clinical Pharmacology and Pharmacokinetics, Greek Edition 2003, 21: 32-33 (2003) 24) Lymperopoulos, A., Taraviras, S., Mastroyianni, O., Stavropoulou, E., Kasimatis, T., and Flordellis, C. Phosphatidylinositol-3 Kinase (PI-3K) Mediates Epinephrine-Induced Survival and Differentiation of PC12- α 2 Cells. Review of Clinical Pharmacology and Pharmacokinetics, International Edition, 16: 15 (2002) 25) Lymperopoulos, A., Schaak, S., Charitonidou, D., Cayla, C., Denis, C., Paris, H., and Flordellis, C. cAMP down-regulates α2C-adrenergic receptor at the transcriptional level in HepG2 cells. NATO/FEBS Advanced Study Institute- International Summer School on «Molecular Mechanisms of Signal Transduction», Island of Spetsai, Greece. Review of Clinical Pharmacology and Pharmacokinetics, International Edition, 13: 61 (1999) Research Financial Support: 1) AHA Scientist Development Grant (SDG) Award (National Center) entitled: “Role of adrenal beta-arrestin-1 in angiotensin II-induced aldosterone production in post-infarct heart failure” (Award ID: 09SDG2010138), PI: Dr. Anastasios Lymperopoulos, Duration: 07/01/2009-06/30/2014, Gross Annual Funding: 77,000 $ 14
A. LYMPEROPOULOS-CV 2) AHA Great Rivers (Formerly: Pennsylvania-Delaware) affiliate Post-Doctoral Research Fellowship, “Role of Adrenal GRKs in Regulation of Sympathetic Nervous System Activity in Heart Failure”, July 2005-July 2008, Thomas Jefferson University, Philadelphia, PA. PI: Dr. Walter J. Koch 3) Co-Investigator, “Adrenal GRKs and Adrenergic Signaling in Heart Failure”, NIH Research Grant: R01 HL085503-01A1, April 2007-July 2009. PI: Dr. Walter J. Koch 4) Nova Southeastern University`s President's Faculty Research & Development Grant (PFRDG)-FY 2014 (NSU intramural grant) entitled: “Angiotensin receptor blockers & beta-arrestin-dependent aldosterone production” (Award ID: PFRDG 335320), PI: Dr. Anastasios Lymperopoulos, Duration: 08/01/2013-07/31/2014, Total Funding: 9,661 $ 5) Nova Southeastern University`s Health Professions Division (HPD) Research Grant (NSU-HPD intramural grant) entitled: “Role of beta-arrestin-1 in aldosterone production from adrenocortical cells” (Award ID: 335797-RX- Lymperopoulos-BetaArrestin1), PI: Dr. Anastasios Lymperopoulos, Duration: 10/01/2011-09/30/2012, Total Funding: 5,000 $ 6) Co-Investigator, “Study of Signal Transduction of cloned α 2 -adrenergic receptors in homologous and heterologous cell lines”. BIOMED II Program, European Union Research Council, 1998-2001. PI: Dr. Chris S. Flordellis 15
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