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NRDC: No Breathing in the Aisles: Diesel Exhaust Inside School ...

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such source category.”<br />

In addition, <strong>the</strong> Food Quality<br />

Protection Act, <strong>the</strong> only law<br />

designed specifically to protect<br />

children from environmental<br />

contam<strong>in</strong>ants, requires EPA to<br />

ensure that <strong>the</strong>re is a reasonable<br />

certa<strong>in</strong>ly that no harm will result<br />

from aggregate exposure to a<br />

pesticide from food and all o<strong>the</strong>r<br />

exposures. This standard has been<br />

<strong>in</strong>terpreted to mean that a<br />

significant risk exists when <strong>the</strong>re is<br />

a 1 <strong>in</strong> 1 million chance that an<br />

effect will occur. 21 U.S.C. §<br />

346a(b)(2)(A)(ii); Letter from<br />

Lynn Goldman, Assistant<br />

Adm<strong>in</strong>istrator of <strong>the</strong> EPA, to<br />

Representative Henry Waxman<br />

(Mar. 17, 1998). The Food<br />

and Drug Adm<strong>in</strong>istration (FDA)<br />

has also generally used a standard<br />

of 1 <strong>in</strong> 1 million or less. 50 Fed.<br />

Reg. 51,551, 51,557 (1985) (to be<br />

codified at 20 C.F.R. 700) ("FDA<br />

cannot, with assurance, state that<br />

<strong>the</strong> 1 <strong>in</strong> 100,000 level would pose<br />

an <strong>in</strong>significant level of risk of<br />

cancer to people. FDA can state,<br />

and comments agree, that <strong>the</strong> 1 <strong>in</strong><br />

1 million level represents an<br />

<strong>in</strong>significant level of risk of cancer<br />

to people.")<br />

28<br />

For a complete list, see Krieger,<br />

et al., “Proposed Identification of<br />

<strong>Diesel</strong> <strong>Exhaust</strong> as a Toxic Air<br />

Contam<strong>in</strong>ant, Part A: Exposure<br />

Assessment,” Technical<br />

Support Document, as approved<br />

by <strong>the</strong> Scientific Review Panel on<br />

April 22, 1998, Appendix A; p. A-<br />

7. The health effects of diesel<br />

exhaust constituents are discussed<br />

<strong>in</strong> Rosenstock, L. and M. Cullen<br />

(eds.), Textbook of Cl<strong>in</strong>ical<br />

Occupational and Environmental<br />

Medic<strong>in</strong>e, Philadelphia, W.B.<br />

Saunders Co., 1994, p. 778; Paul,<br />

M. (ed.), Occupational and<br />

Environmental Reproductive<br />

Hazards: A Guide for Cl<strong>in</strong>icians,<br />

Philadelphia, Williams and<br />

Wilk<strong>in</strong>s, 1993, pp. 234-48, 273-4;<br />

Birnbaum, L., “Developmental<br />

Effects of Diox<strong>in</strong>s and Related<br />

Endocr<strong>in</strong>e Disrupt<strong>in</strong>g Chemicals,”<br />

Lett. Toxicol., 1995, pp. 82/83,<br />

743–750.<br />

29<br />

Gauderman, W. James, et al.,<br />

“Association between Air<br />

Pollution and Lung Function<br />

Growth <strong>in</strong> Sou<strong>the</strong>rn California<br />

Children,” May 2, 2000.<br />

60<br />

30<br />

California Energy Commission,<br />

“Safe <strong>School</strong> bus Clean Fuel,”<br />

Efficiency Demonstration<br />

Program, Second Interim Status<br />

Report, May 1999, p. 3.<br />

31<br />

Dawson, et al., “Proposed<br />

Identification of <strong>Diesel</strong> <strong>Exhaust</strong> as<br />

a Toxic Air Contam<strong>in</strong>ant, Part B:<br />

Health Risk Assessment for <strong>Diesel</strong><br />

<strong>Exhaust</strong>,” Public and Scientific<br />

Review Panel Review Draft,<br />

February 1998, pp. 1-8—1-9.<br />

32 Natural Resources Defense<br />

Council, “<strong>Exhaust</strong>ed by <strong>Diesel</strong>:<br />

How America’s Dependence on<br />

<strong>Diesel</strong> Eng<strong>in</strong>es Threatens Our<br />

Health,” 1998, p. 6.<br />

33<br />

Id.<br />

34<br />

South Coast Air Quality<br />

Management District, “Multiple<br />

Air Toxics Exposure Study <strong>in</strong> <strong>the</strong><br />

South Coast Air Bas<strong>in</strong> (MATES-<br />

II),” March 2000, p. ES-3.<br />

35<br />

South Coast Air Quality<br />

Management District, “Multiple<br />

Air Toxics Exposure Study <strong>in</strong> <strong>the</strong><br />

South Coast Air Bas<strong>in</strong> (MATES-<br />

II),” March 2000, p. ES-3.<br />

California Air Resources Board,<br />

“Risk Reduction Plan to Reduce<br />

Particulate Matter Emissions From<br />

<strong>Diesel</strong>-Fueled Eng<strong>in</strong>es and<br />

Vehicles,” July 13, 2000 (draft), p.<br />

15.<br />

36<br />

South Coast Air Quality<br />

Management District, Technology<br />

Advancement Office, January<br />

2001.<br />

37<br />

State and Territorial Air<br />

Pollution Program Adm<strong>in</strong>istrators<br />

and <strong>the</strong> Association of Local Air<br />

Pollution Control Officials,<br />

“Cancer Risk from <strong>Diesel</strong><br />

Particulate: National and<br />

Metropolitan Area Estimates for<br />

<strong>the</strong> United States,” March 15,<br />

2000.<br />

38<br />

STAPPA/ALAPCO press<br />

release, “More than 125,000 to Get<br />

Cancer From <strong>Diesel</strong> Fumes,<br />

Concludes New State-Local<br />

Government Analysis,” March 15,<br />

2000.<br />

39<br />

Cackette, Tom, “Importance of<br />

Reduc<strong>in</strong>g Emissions From Heavy-<br />

Duty Vehicles,” California Air<br />

Resources Board, October 5,<br />

1999, p. 15.<br />

40<br />

Bagley, Susan T., et al., Health<br />

Effects Institute, “Characterization<br />

of Fuel and Aftertreatment Device<br />

Effects of <strong>Diesel</strong> Emissions,”<br />

Research Report Number 76,<br />

September, 1996.<br />

41<br />

M. Lippmann, “Environmental<br />

Toxicants: Human Exposures and<br />

Their Health Effects,” Van<br />

<strong>No</strong>strand Re<strong>in</strong>hold, 1992, pp. 16-<br />

17.<br />

42<br />

Dockery, D.W., et al., “An<br />

Association Between Air Pollution<br />

and Mortality <strong>in</strong> Six U.S. Cities,”<br />

New England Journal of<br />

Medic<strong>in</strong>e, 329,1993: 1753-59;<br />

Pope III, C.A., et al., “Particulate<br />

Air Pollution as a Predictor of<br />

Mortality <strong>in</strong> a Prospective Study<br />

of U.S. Adults,” Am. J. Resp. Crit.<br />

Care Med, 151, 1995: 669-674;<br />

Shprentz, D., “Breathtak<strong>in</strong>g:<br />

Premature Mortality Due to<br />

Particulate Air Pollution <strong>in</strong> 239<br />

American Cities,” New York,<br />

<strong>NRDC</strong>, May 1996, pp. 13-32.<br />

43<br />

D.W. Dockery, et al., “An<br />

Association Between Air Pollution<br />

and Mortality <strong>in</strong> Six U.S. Cities,”<br />

New England Journal of<br />

Medic<strong>in</strong>e, 329,1993: 1753-59;<br />

C.A. Pope III, et al., “Particulate<br />

Air Pollution as a Predictor of<br />

Mortality <strong>in</strong> a Prospective Study<br />

of U.S. Adults,” Am. J. Resp. Crit.<br />

Care Med, 151, 1995: 669-674;<br />

Shprentz, D., “Breathtak<strong>in</strong>g:<br />

Premature Mortality Due to<br />

Particulate Air Pollution <strong>in</strong> 239<br />

American Cities,” New York,<br />

<strong>NRDC</strong>, May 1996, pp. 13-32.<br />

44<br />

Hiura, T.S., et al., “Chemicals<br />

<strong>in</strong> <strong>Diesel</strong> <strong>Exhaust</strong> Particles<br />

Generate Reactive Oxygen<br />

Radicals and Induce Apoptosis <strong>in</strong><br />

Macrophages,” J. Immunol., Vol<br />

163, <strong>No</strong>. 101999 5582-91; O.<br />

Fahy, et al., “Effects of <strong>Diesel</strong><br />

Organic Extracts on Chemok<strong>in</strong>e<br />

Production by Peripheral Blood<br />

Mononuclear Cells,” J. Allergy<br />

Cl<strong>in</strong>. Immunol., 103(6)1999:1115-<br />

24.<br />

45<br />

Dockery, D.W., et al., “An<br />

Association Between Air Pollution<br />

and Mortality <strong>in</strong> Six U.S. Cities,”<br />

New England J. Med, 329(24):<br />

1753-9, 1993.<br />

46<br />

Harvard <strong>School</strong> of Public<br />

Health Press Release, “F<strong>in</strong>e<br />

Particle Air Standards <strong>No</strong>t<br />

Sufficient to Protect Public<br />

Health,” December 6, 1993.<br />

47<br />

Pope III, C.A., et al.,<br />

“Particulate Pollution as a<br />

Predictor of Mortality <strong>in</strong> a<br />

Prospective Study of U.S. Adults,”<br />

Am. J. Resp. Crit. Care Med;<br />

151:669-74, 1995.<br />

48<br />

Morbidity and Mortality<br />

Weekly Report, 41(39), Oct 2,<br />

1992, pp. 735-773.<br />

49<br />

Miyamoto, T., “Epidemiology<br />

of Pollution-Induced Airway<br />

Disease <strong>in</strong> Japan,” Allergy; 52(38<br />

Suppl): 30-34, 1997; Albright, J.F.<br />

and R.A. Goldste<strong>in</strong>, “Airborne<br />

Pollutants and <strong>the</strong> Immune<br />

System,” Otolaryngol Head Neck<br />

Surg; 114(2):232-8, 1996; Sagai,<br />

M., A. Furuyama and T. Ich<strong>in</strong>ose,<br />

“Biological Effects of <strong>Diesel</strong><br />

<strong>Exhaust</strong> Particles (DEP):<br />

Pathogenesis of Asthma Like<br />

Symptoms <strong>in</strong> Mice,” Free Radic.<br />

Biol. Med., 21(2):199-209, 1996.<br />

50<br />

Miyabara, Y., H. Takano, T.<br />

Ich<strong>in</strong>ose, H. Lim, M. Sagai,<br />

“<strong>Diesel</strong> <strong>Exhaust</strong> Enhances Allergic<br />

Airway Inflammation and<br />

Hyperresponsiveness <strong>in</strong> Mice.”<br />

Am. J. Resp. Crit. Care Med.<br />

157:1-7 (1998).<br />

51<br />

Ishizaki T., K. Koizomi, R.<br />

Ikemori, Y. Ishiyama, E.<br />

Kushibiki, “Studies of Prevalence<br />

of Japanese Cedar Poll<strong>in</strong>osis<br />

Among Residents <strong>in</strong> a Densely<br />

Cultivated Area.” Allergy 58:265-<br />

270 (1987).<br />

52<br />

Diaz-Sanchez, D., K. Zhang, A.<br />

Tisen, J. Flemm<strong>in</strong>g, A. Saxon,<br />

“Comb<strong>in</strong>ed <strong>Diesel</strong> <strong>Exhaust</strong><br />

Particulate and Ragweed Allergen<br />

Markedly Enhances <strong>in</strong> Vivo Nasal<br />

Ragweed-Specific Ig E and Shows<br />

Cytok<strong>in</strong>e Production to a TH2-<br />

Type Pattern,” J. Immunol. 158:<br />

2406-2413 (1997).<br />

53<br />

Lipsett, “The Hazards of Air<br />

Pollution to Children,” <strong>in</strong> S.<br />

Brooks, et al. (eds) Environmental<br />

Medic<strong>in</strong>e, St. Louis: Mosby, 1995.

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