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Radiology Case Presentation - Henry Ford Health System

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Osteosarcoma<br />

• Malignant mesenchymal sarcoma<br />

– Tumor cells arise from primitive mesenchymal boneforming<br />

cells<br />

• Conventional osteosarcoma: 75%<br />

– Subclassification<br />

• Osteoblastic: Majority of tumor cells produce osteoid<br />

• Chrondroblastic: Majority of cells produce chondroid matrix<br />

• Fibroblastic: Spindle cells predominate; little matrix formed<br />

• Variants: 25%

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