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Evidence-Based Medicine

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Systematic review<br />

A type of review article that uses explicit methods to comprehensively analyze<br />

and qualitatively synthesize information from multiple studies. Aystamatic<br />

Review is a literature review focused on a single question which tries to identify,<br />

appraise, select and synthesis all high quality research evidence relevant to<br />

that question. A review in which specified and appropriate methods have<br />

been used to identify, appraise, and summarise studies addressing a defined<br />

question. It can, but need not, involve meta-analysis.<br />

The present requirements for reporting systematic reviews are search date,<br />

number of trials of the relevant option, number of trials that perform the<br />

appropriate comparisons, comparisons, details on the type of people, follow up<br />

period, and quantified results if available.<br />

T<br />

True negative<br />

A person without the target condition (defined by a gold standard) who has a<br />

negative test result.<br />

True positive<br />

A person with the target condition (defined by a gold standard) who also has a<br />

positive test result.<br />

V<br />

Validity<br />

The soundness or rigour of a study. A study is internally valid if the way it is<br />

designed and carried out means that the results are unbiased and it gives you<br />

an accurate estimate of the effect that is being measured. A study is externally<br />

valid if its results are applicable to people encountered in regular clinical<br />

practice.<br />

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