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Evidence-Based Medicine

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W<br />

Weighted mean difference (WMD)<br />

A measure of effect size used when outcomes are continuous (such as symptom<br />

scores or height) rather than dichotomous (such as death or myocardial<br />

infarction). The mean differences in outcome between the groups being studied<br />

are weighted to account for different sample sizes and differing precision<br />

between studies. The WMD is an absolute figure and so takes the units of the<br />

original outcome measure.<br />

A continuous outcome measure, similar to standardised mean differences but<br />

based on one scale so in the real units of that scale. Ideal ly should be replaced<br />

by a discrete outcome and a relative risk; however, we use WMD if this is not<br />

possible.<br />

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