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2010 Chapter 8 homework SOLUTIONS _v2 - Department of ...

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32. Complete the following retrosynthesis problems by writing in the appropriate reagents. No more<br />

than two steps are required for each <strong>of</strong> the following transformations.<br />

Cl<br />

Magnesium metal<br />

ether solvent<br />

MgCl<br />

Br<br />

OCH 3<br />

lithium metal<br />

ether solvent<br />

Li<br />

OCH 3<br />

Br<br />

1. Mg, ether<br />

2. dilute HCl<br />

H<br />

CH 2 Cl<br />

1. Li, ether<br />

2. O<br />

(<strong>Chapter</strong> 9)<br />

CH 2 CH 2 CH 2 OH<br />

O<br />

CH 3<br />

1. CH 3 CH 2 CH 2 MgBr<br />

OHCH 3<br />

2. dilute HCl<br />

CH 2 CH 2 CH 3<br />

© <strong>2010</strong>, Pr<strong>of</strong>. S. R. Hitchcock, <strong>Department</strong> <strong>of</strong> Chemistry, Illinois State University, Normal, IL 61790-4160 20

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