20.01.2015 Views

Prohibited Ingredients - TTB

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<strong>Prohibited</strong> <strong>Ingredients</strong> (Continued)<br />

• Coloring Material:<br />

– Added to impart a color which in not natural<br />

to the product<br />

– FD&C Certified (allowed) — Yellow #5 (tartrazine) must be<br />

declared on the label<br />

– Noncertified (allowed) — Examples are paprika, saffron,<br />

beet extract, caramel<br />

– Noncertified synthetic dye (prohibited)<br />

– Developed an HPLC method using DAD, in the process of<br />

validating this method, 26 total dyes in library — ODS<br />

column, phosphate buffer and methanol as mobile phase,<br />

gradient

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