Human Arterial Tree Simulation on TeraGrid - Center for Fluid ...
Human Arterial Tree Simulation on TeraGrid - Center for Fluid ...
Human Arterial Tree Simulation on TeraGrid - Center for Fluid ...
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<str<strong>on</strong>g>Human</str<strong>on</strong>g> <str<strong>on</strong>g>Arterial</str<strong>on</strong>g> <str<strong>on</strong>g>Tree</str<strong>on</strong>g><br />
<str<strong>on</strong>g>Simulati<strong>on</strong></str<strong>on</strong>g> <strong>on</strong> <strong>TeraGrid</strong><br />
The CRUNCH group is a research group in the Divisi<strong>on</strong> of Applied Mathematics<br />
at Brown University. The thrust of its research is the development of numerical<br />
algorithms, visualizati<strong>on</strong> methods and parallel software <strong>for</strong> c<strong>on</strong>tinuum and<br />
atomistic simulati<strong>on</strong>s in fluid mechanics and related applicati<strong>on</strong>s.<br />
Sketch of the human<br />
vascular system<br />
<str<strong>on</strong>g>Arterial</str<strong>on</strong>g> <str<strong>on</strong>g>Tree</str<strong>on</strong>g> Project<br />
Cranial arteries rec<strong>on</strong>structed<br />
from MRI images with gOREK<br />
! Goal: to model blood flow interacti<strong>on</strong>s in different<br />
regi<strong>on</strong>s of the cardiovascular system.<br />
! High-per<strong>for</strong>mance computing is essential <strong>for</strong> modeling<br />
3D unsteady fluid mechanics in arterial systems.<br />
! Accurately capturing flow dynamics requires high<br />
spatial resoluti<strong>on</strong> and meshes with milli<strong>on</strong>s of elements.<br />
! CFD code NEKTAR-G2, developed at Brown, is based<br />
<strong>on</strong> spectral/hp element methods; NEKTAR-G2 can<br />
efficiently handle cross-site simulati<strong>on</strong>s <strong>on</strong> the <strong>TeraGrid</strong>.<br />
! Recent simulati<strong>on</strong>s of 3D flow in the cranial vascular<br />
system involved 65 arteries and the soluti<strong>on</strong> of flow<br />
equati<strong>on</strong>s with over a billi<strong>on</strong> degrees of freedom.<br />
Collaborators:<br />
Brown University<br />
Leopold Grinberg<br />
Susanna Makela<br />
George Karniadakis<br />
Arg<strong>on</strong>ne Nati<strong>on</strong>al Lab<br />
Joseph Insley<br />
Mike Papka<br />
NIU/Arg<strong>on</strong>ne<br />
Nicholas Kar<strong>on</strong>is<br />
Brian To<strong>on</strong>en<br />
Imperial College, UK<br />
Spencer Sherwin<br />
Children's Hospital,<br />
Harvard Medical School<br />
Tomer Anor<br />
Joseph Madsen<br />
Supported by an NSF CI-TEAM grant.<br />
Special thanks to Leland James<strong>on</strong>, Frederica<br />
Darema, and Almadena Chtchelkanova.
Parallel Paradigm <strong>on</strong> <strong>TeraGrid</strong><br />
To handle the computati<strong>on</strong>al demands of these simulati<strong>on</strong>s we turn to the<br />
supercomputing resources offered by the <strong>TeraGrid</strong>, a network integrating powerful<br />
open computing resources in the USA. We are working closely with computer<br />
scientists at Northern Illinois University and Arg<strong>on</strong>ne Nati<strong>on</strong>al Lab to develop<br />
middleware that can facilitate in the transiti<strong>on</strong>ing of simulati<strong>on</strong> executi<strong>on</strong>s from a<br />
single supercomputer to a cluster of supercomputers such as the <strong>TeraGrid</strong>. In<br />
particular, we have focused <strong>on</strong> the use and further development of MPIg, which,<br />
through services provided by the Globus Toolkit, relieves the computati<strong>on</strong>al scientist<br />
from low-level details of secure process management, communicati<strong>on</strong>, and network<br />
topology.<br />
We aim to establish a biomechanics gateway <strong>on</strong> the <strong>TeraGrid</strong> and make the arterial<br />
tree a plat<strong>for</strong>m and a simulati<strong>on</strong> framework <strong>for</strong> further developments and systematic<br />
studies in hemodynamics, disease modeling, and drug delivery.<br />
Computati<strong>on</strong><br />
Visualizati<strong>on</strong><br />
Viewer client: SC07, Reno, NV<br />
Flow data<br />
Servers<br />
Globus handles<br />
secure process<br />
management,<br />
MPIg handles<br />
communicati<strong>on</strong>s<br />
For more in<strong>for</strong>mati<strong>on</strong>, visit http://www.cfm.brown.edu/crunch/ATREE/index.html