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Company presentation - Mondobiotech

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The orphan market<br />

• Worldwide, the orphan drug market reached<br />

$84.9 billion in 2009. The market is expected<br />

to grow at a compound annual growth<br />

rate (CAGR) of nearly 6% to reach $112.1 billion<br />

by 2014. The US accounted for 51% of the<br />

market in 2009 and is expected to grow at<br />

a CAGR of 8.9% to reach $65.9 billion by 2014.<br />

• The total worldwide market for orphan<br />

drugs, including sales for non-orphan<br />

applications, exceeded $28 billion in 2003. The<br />

market reached $58.7 billion in 2006, growing<br />

by 8% from $54.5 billion in 2005<br />

in orphan applications only.<br />

• Biological drugs accounted for a major share<br />

(64.3%) of the orphan drug market with sales<br />

of $54.6 billion in 2009, up from $51.4 billion<br />

(Source: www.bccresearch.com/report/PHM038C.html, published:<br />

May 2010, analyst: Syamala Ariyanchira, and reports of 2004 and 2007)<br />

in 2008. The size of the biological orphan drug<br />

market is projected to grow<br />

at a 6.9% CAGR to reach $76.2 billion by 2014.<br />

• In 2009 there were a total of more then<br />

350 orphan drugs approved in USA<br />

and 62 in Europe.<br />

• 57 drugs exceeded yearly sales of $200<br />

million and 27 of those exceeded sales<br />

of $1 billion.<br />

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