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Brian Cullis

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Linear mixed model<br />

The model<br />

Let y (n×1) be vector of observations. The general linear mixed<br />

model can be written as<br />

y = Xτ +Zu+e<br />

• τ (p×1) vector of fixed effects with design matrix X<br />

(assumed full rank)<br />

• u (b×1) vector of random effects with design matrix Z<br />

• e (n×1) vector of residuals.<br />

VSN Applied Statistics Conference 2011<br />

Modelling variance structures of multi-term effects

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