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Chapter 3 Resource: Interactions of Human Systems

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Name Date Class<br />

2<br />

Enrichment<br />

Enzymes and Coenzymes<br />

Meeting Individual Needs<br />

Our bodies require energy to live. To get that<br />

energy from the food we eat, the food must first<br />

be processed by our digestive system, then<br />

absorbed by all <strong>of</strong> our cells. Our bodies perform<br />

two types <strong>of</strong> digestion simultaneously: physical<br />

breakdown and chemical breakdown. Physical<br />

breakdown is smashing food into smaller pieces.<br />

Chemical breakdown involves separating the<br />

molecules in the food and then digesting, or<br />

breaking apart, the bonds the molecules contain.<br />

Essential to chemical digestion are many<br />

enzymes that help perform molecular digestion<br />

at various stages <strong>of</strong> the digestive process.<br />

Shaping Up<br />

Each enzyme has a unique number <strong>of</strong> atoms<br />

and a unique shape. The shape <strong>of</strong> the enzyme<br />

determines it’s function. For example, amylase is<br />

an enzyme that helps break down starches. The<br />

enzyme and the starch fit together like two puzzle<br />

pieces, each fitting exactly only with the<br />

other. However, enzymes require other molecules<br />

to ensure proper activity. These molecule<br />

are called coenzymes.<br />

Many coenzymes are vitamins. If a person is<br />

not consuming a proper diet, complete with all<br />

vitamins and minerals, certain enzyme<br />

processes may not function properly. Many<br />

medical problems are linked with low levels, or<br />

even the absence, <strong>of</strong> certain enzymes.<br />

1. What is the function <strong>of</strong> a digestive enzyme<br />

A condition known as lactose intolerance is a<br />

common condition in which a body can’t digest<br />

lactose, the sugar in milk products. If a person<br />

lacks the lactose-digesting enzyme, lactase, that<br />

person may need to reduce or eliminate milk<br />

products from his or her diet, or possibly take<br />

enzyme supplements. While lactose intolerance<br />

is not life threatening, it causes increased gas<br />

production, upset stomach, or intestinal distress.<br />

Serious Problems<br />

Some enzyme deficiencies, such as Gaucher’s<br />

disease, can be more serious. This disease is<br />

caused by a deficiency in the enzyme that<br />

digests glycolipids (glucose combined with fats<br />

or oils). Without this enzyme, blood levels <strong>of</strong><br />

glycolipids can increase and cause serious problems.<br />

These problems may include an enlarged<br />

spleen and liver, anemia (low blood oxygen),<br />

and severe bone and joint pain.<br />

For those people who have enzyme deficiencies,<br />

identified by a physician, enzyme supplements<br />

<strong>of</strong>fer one possible treatment. Most<br />

medical pr<strong>of</strong>essionals agree, however, that<br />

healthy people manufacture all the enzymes<br />

they require, so supplements are not necessary.<br />

Further, most digestive problems are correctable<br />

by making sure a proper diet is consumed that<br />

provides the body with all the nutrients it needs<br />

to maintain the right levels <strong>of</strong> enzyme activity.<br />

2. What gives enzymes the ability to digest the molecules they are supposed to digest<br />

3. A person may show symptoms <strong>of</strong> reduced enzyme function. Explain how this may be caused<br />

by a vitamin or mineral deficiency.<br />

4. How do you think digestive enzymes assist the body in maintaining overall homeostasis<br />

Copyright © Glencoe/McGraw-Hill, a division <strong>of</strong> the McGraw-Hill Companies, Inc.<br />

32 <strong>Interactions</strong> <strong>of</strong> <strong>Human</strong> <strong>Systems</strong>

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