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Acute lung injury (ALI) and Acute respiratory distress syndrome ...

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Ventilator procedures<br />

12 ml/kg Group<br />

•Initial Vt = 12 ml/kg PBW<br />

•If Pplat > 50 cmH 2 0, reduce Vt<br />

•Minimum Vt = 4 ml/kg<br />

6 ml/kg Group<br />

•Initial Vt = 6 ml/kg PBW.<br />

•If Pplat > 30 cmH 2 0, reduce Vt.<br />

•Minimum Vt = 4 ml/kg<br />

24<br />

20<br />

PEEP<br />

16<br />

12<br />

8<br />

4<br />

0<br />

0.3 0.4 0.4 0.5 0.5 0.6 0.7 0.7 0.8 0.9 0.9 0.9 1.0 1.0 1.0<br />

FIO2<br />

PaO 2 = 55 - 80 mmHg or SpO 2 = 88 - 95%<br />

St<strong>and</strong>ardized weaning protocol

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