Cardiovascular Trials Review Cardiovascular Trials Review - Diegori.it
Cardiovascular Trials Review Cardiovascular Trials Review - Diegori.it
Cardiovascular Trials Review Cardiovascular Trials Review - Diegori.it
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MIRACL<br />
Myocardial Ischemia Reduction w<strong>it</strong>h Aggressive Cholesterol<br />
Lowering (Substudy)<br />
T<strong>it</strong>le<br />
Authors<br />
Effects of atorvastatin on stroke in patients w<strong>it</strong>h unstable<br />
angina or non-Q-wave myocardial infarction.<br />
Waters DD, Schwartz GG, Olsson AG, et al.<br />
Reference Circulation 2002;106:1690–1695.<br />
Disease<br />
Purpose<br />
Design<br />
Patients<br />
Follow-up<br />
Regimen<br />
Hypercholesterolemia; unstable angina, non-Q-wave<br />
myocardial infarction; stroke.<br />
To determine whether aggressive lowering of lipid levels<br />
w<strong>it</strong>h a statin reduces the incidence of nonfatal stroke<br />
in patients who have had an acute coronary syndrome.<br />
Substudy of a randomized, placebo-controlled trial.<br />
As per MIRACL.<br />
16 weeks.<br />
Patients were randomized to atorvastatin (n=1538)<br />
80mg/d or placebo (n=1548) for 16 weeks. All patients<br />
were counseled on adherence to the National Cholesterol<br />
Education Program Step I diet.<br />
Section 8<br />
8. Lipid-Lowering Studies<br />
839
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