Cone biopsy of cervix - Rcpa.tv

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Immunoperoxidase stains • Ki67 (MIB1) immunostain is a proliferation marker • Positive defined as nuclear staining <strong>of</strong> any degree • CIN shows positive staining suprabasilar squamous cells
Ki67 immunostain • Positive cells in all parts <strong>of</strong> the squamous epithelium • Non-dysplastic epithelium shows scattered isolated cells in only the basal layers.
Page 1 and 2: Cone biopsy of cervix. An example o
Page 3 and 4: Terminology • Cervical intraepith
Page 5 and 6: Contents of histology report • Pa
Page 7 and 8: Macroscopic description 4. Ink 12 o
Page 9 and 10: Mark margins The anterior half of t
Page 11 and 12: Sagittal sections for processing. 1
Page 13 and 14: Microscopic description 4. Assess b
Page 15 and 16: Cervical squamous dysplasia • CIN
Page 17 and 18: Microscopic description Transformat
Page 19 and 20: Microscopic description • Squamou
Page 21 and 22: Microscopic description • Must al
Page 23: P16 immunostain • Nuclear and cyt
Page 27: References • The Bethesda system

Cone biopsy of cervix - Rcpa.tv

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