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Prominence UFLC / UFLCXR

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Aiming for Faster Separation with<br />

Uncompromising Quality<br />

<strong>Prominence</strong> <strong>UFLC</strong> System<br />

The times call for ultra-high-speed LC. Adopting ultra-high-speed LC<br />

for a range of analysis work can provide a variety of benefits.<br />

However, it is not enough to simply reduce analysis times. It is also<br />

important to maintain basic precision in LC analysis, including<br />

retention time repeatability, injection repeatability via an autosampler,<br />

and carryover and detector sensitivity. Furthermore, in selecting<br />

equipment, high-speed analysis means little without system durability<br />

and operability.<br />

The <strong>Prominence</strong> <strong>UFLC</strong> is the optimal system for any laboratory striving<br />

for truly high-throughput analysis.<br />

Unquestionable Fidelity - Both Repeatability and Speed<br />

Maximizing Data Reliability<br />

For precise equipment control, required by analytical validation<br />

processes and quality control tests, and for minimizing the risk of a<br />

system malfunction interrupting an analysis, the most important<br />

factor is the 6-port valve on the autosampler. The <strong>Prominence</strong> <strong>UFLC</strong><br />

uses Shimadzu’s own proprietary high-precision 6-port valve, which<br />

achieves 0.3% or less (RSD) area repeatability in 100,000 cycle<br />

endurance tests* 1 .<br />

In addition, for LC-MS analyses where reduction of sample carryover<br />

has currently gained a great deal of attention, <strong>Prominence</strong> <strong>UFLC</strong><br />

successfully reduces carryover based on the principle of inhibiting the<br />

adsorption of samples in the first place.<br />

* 1 Based on Shimadzu endurance test parameters.<br />

<br />

mAU<br />

240<br />

200<br />

150<br />

100<br />

50<br />

Peaks<br />

Acetophenone<br />

Propiophenone<br />

Butyrophenone<br />

Valerophenone<br />

Retention Time<br />

Area<br />

Average %RSD Average %RSD<br />

0.916<br />

1.398<br />

2.111<br />

3.341<br />

0.089<br />

0.058<br />

0.030<br />

0.031<br />

312,670<br />

315,739<br />

336,428<br />

296,609<br />

0.059<br />

0.045<br />

0.063<br />

0.040<br />

(5 µL injection, n=6)<br />

0<br />

-10<br />

0.0<br />

0.5 1.0 1.5 2.0 2.5 3.0 3.5 min<br />

4

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