Bioquell | Z-2 - Labotal.co.il

Bioquell | Z-2
• Large scale room/zone bio-decontamination
• Parametric cycle control
• Simple to operate “plug and play” system
• Excellent material compatibility including
sensitive electronics

Bioquell Z-2 hydrogen peroxide vapour (HPV) room/zone
bio-decontamination system
The Bioquell Z-2 is a complete solution for room/zone bio-decontamination,
offering user-friendly operation with unique parametric cycle control, eliminating
the necessity for gas cycle development studies (non-GMP facilities).
The Bioquell Z-2 incorporates a HPV generator, gas distribution and catalytic
aeration in a single mobile system. The system is easily operated with user-friendly
touch screen controls and can bio-decontaminate areas up to 250m 3 , using
parametric control (larger volumes can be validated using timed cycles).
Features in brief
• Simple menu-driven user interface to set cycle parameters
• Graphical display of bio-decontamination cycle progress in real time
• Communication port allows control via a building management system (BMS)
• Bioquell dual-circuit technology for fast, efficient bio-decontamination cycles
• No need for room pre-conditioning or dehumidification
• System includes room measuring device and hand-held H 2
O 2
monitoring device
Bioquell hydrogen peroxide solution
Cycle conditions and progress is
recorded via the integral printer
• Bioquell hydrogen peroxide is specified
and approved for use with Bioquell
HPV generators
• Approved for use as a biocide by regulatory
bodies (BPD, EPA)
• Selected for optimal biocidal effectiveness
• Available in 0.5 litre, 1 litre and 5 litre bottles
Standard accessories include:
Hand-held laser dimension finder
Hand-held HPV detector
Ancillary equipment neatly
stored in the lectern

Safe and simple to operate
1
The control lectern
is removed from
the Bioquell Z-2
at an appropriate
control point; the
Bioquell Z-2 is
then placed inside
the contaminated
zone
2
With the lectern
in place outside
the area to be
decontaminated,
the area is sealed
with tape and
any ventilation
systems are
isolated
3
Room dimensions
are entered
allowing the
Bioquell Z-2 to
calculate HPV
cycle parameters.
Final safety checks
are made via the
control panel on
the lectern. The
cycle can then be
activated
4
Multi-directional
nozzles deliver
the vapour,
switching to
automatic
aeration (via
parametric
control) after the
gassing phase is
complete
5 6
The touch screen
displays the
cycle progress
and indicates
when the cycle is
complete
At the end of the
cycle, HPV levels
are manually
checked from
outside the room
and the area is
then rapidly put
back into service
Validation and service
Fully validatable to comply with requirements
of GMP using GAMP-compliant software.
Bioquell provides a complete service including:
• Installation and integration
• Preventative maintenance plans
• Extensive field-based service
engineer network
• IQ/OQ/PQ documentation and execution
• Bio-decontamination cycle development
services (if GMP facility and not using
parametric control)
• Ongoing MQ and RQ support*
*Provided as part of a preventative maintenance plan

Unit part number
230V
120V
100V
Materials of construction
TD068-0000-230V
TD068-0000-120V
TD068-0000-100V
Temperature
Operating 15°C to 30°C
Storage 0°C to 35°C
Relative humidity
Operating
Storage
Power requirements
Power supply
Power consumption
230V
115V
100V
Operating position
Pollution degree environment 2
Dimensions (WxHxD)
With lectern
Without lectern
Weight
With lectern
Lectern
Maximum liquid volume
Control system
Airflow rates
Vapour
Air distribution
Aeration
Temperature of vapour supply
H 2
O 2
liquid injection rate
230V
120V/100V
Polypropylene (PP), acrylonitrile butadiene
styrene, polycarbonate mix (ABS/PC), (ABS),
aluminium, stainless steel, polyvinylchloride (PVC)
80% RH (maximum)
80% RH (maximum non-condensing)
AC 230V 50/60 Hz 13 amps
AC 120V 50/60 Hz 12 amps
AC 100V 50/60Hz 15 amps
Installation category II
3kW
1.4kW
1.5kW
Upright only
660 x 1444 x 710mm
660 x 1444 x 560mm
95 kg
11.5 kg
4.3 litres (usable)
Siemens ® S7 200 PLC
50 m 3 /hr
800 m 3 /hr
1000 m 3 /hr
50-70°C
20 g/min
10 g/min
Catalyst HEPA efficiency 99.997%
Noise
Hydrogen peroxide
78 dBA (in aeration)
30-35% w/w Bioquell hydrogen peroxide (stored at 2-8°C)
Features in brief
• Dual circuit technology for optimum
cycle times
• Gas distribution catalytic aerator included
• Siemens ® colour touch screen
• GAMP compliant software
• Compact and highly portable design
• Easily cleanable external surface
• Volt-free contacts for external signals
• Integral thermal paper printer
• Remote start/stop
• Unique Bioquell parametric control process
– no need for gas cycle development
• Cycle edit and store facility for new applications
• Effective against a wide range of micro-organisms
• Hydrogen peroxide vapour gas sensor

Hydrogen peroxide vapour (HPV) technology
HPV concentration
t=0*
1
2
3
Inactivation of micro-organisms
GASSING DWELL AERATION
TIME
* Conditioning phase not shown (vaporiser reaches temperature)
Note: “features” on graph change e.g. depending on size of
chamber (& related temperature effect)
4
5
Schematic of Bioquell HPV concentration/time graph
1. HPV introduced – initial rapid increase in HPV concentration
2. HPV saturation/“dew point” achieved – onset of rapid bio-decontamination
3. HPV gassing plateau – sustained micro-condensation effecting bio-deactivation
4. Dwell period (contact time)
5. Aeration – removal of HPV from the atmosphere typically by catalytic
conversion to water vapour and oxygen, leaving no residues
Schematic of dew point and Bioquell kill dynamics
1. Injection of HPV into the enclosure starts (t=0)
2. Only slight decline in biological indicator population prior to dew point
3. Rapid micro-biological kill occurs immediately after saturation/“dew point” is achieved –
process optimised to achieve reliable 6-log sporicidal reduction on all exposed surfaces
4. Onset of micro-condensation correlates with rapid bio-deactivation
5. Bio-deactivation achieved via micro-condensation (invisible layer) of hydrogen
peroxide (2-6µm)
* Typical BI: Tyvek ® pouched 6-log
Geobacillus stearothermophilus spores
Key benefits of HPV
• Excellent material compatibility
including sensitive electronics
• Environmentally friendly –
“residue-free” (breaks down to
water vapour and oxygen)
• Effective against a wide range
of micro-organisms
• High level disinfection achieved
(6-log sporicidal reduction)
• Low temperature
bio-decontamination process
HPV applications
• GMP cleanrooms
• Aseptic processing
• Biologics
• Biomedical
• Biosafety/security
Key features and benefits of the Bioquell Z-2
FEATURES
Unique Bioquell parametric control algorithm
Complete system incorporating gas distribution
and catalytic aeration
Fast, high capacity HPV vaporiser
Fully compliant with GMP requirements
Mobile system
BENEFITS
Fast, efficient cycles with no need for gas cycle
development
Single system HPV for the complete
bio-decontamination process
Quick bio-decontamination of volumes up to 250m 3 , using parametric
control (larger areas can be validated using timed cycles)
Able to be used in regulated areas (if used with
timed HPV cycles)
Can be easily moved to areas requiring
bio-decontamination

Other unique bio-decontamination
solutions from Bioquell
Bioquell RBDS rapid facility bio-decontamination service
A unique bio-decontamination service from Bioquell
for zones, rooms and buildings:
• “Infinitely scalable” – no room or building too large
• Emergency, scheduled, contract or new-build
• Rapid deployment by highly trained Bioquell technicians
Bioquell Material Transfer Solutions
Bio-decontamination chambers:
• Material transfer incorporating HPV bio-decontamination
at ambient temperature
• Rapid decontamination leading to fast material transfer
• Inflatable door seals for reliable, safe operation
Bioquell Clarus L2
Multi-function HPV generator for small rooms, enclosure
and equipment.
• Fixed or mobile configurations up to 75m 3
• Capable of 6-log sporicidal reduction
• Fast, validatable bio-decontamination
Disclaimer: Bioquell UK Ltd or its affiliates, distributors, agents or licensees (together
‘Bioquell’) reserves the right to change the specification of the Bioquell Z-2 without
notice. In addition, Bioquell makes no claims as to the guarantee of sterilisation
using these products; however, Bioquell recommends that customers ensure that
the requisite level of bio-decontamination is achieved using standard biological
indicators such as 6-log Geobacillus stearothermophilus spores; and the Bioquell
Z-2, subject to appropriate cycle development, is designed to be able to provide such
levels of bio-deactivation.
Your local distributor:
Clarus / Bioquell / RBDS are registered trade marks of Bioquell UK Ltd.
© Bioquell UK Ltd (2010). All rights reserved.
For further information on Bioquell’s technology:
E: info@bioquell.com
W: www.bioquell.com
Bioquell UK Ltd
T: +44 (0)1264 835 835
Bioquell Ireland
T: +353 (0)61 603 622
Bioquell Inc
T: +1 (215) 682 0225
Bioquell SAS
T: +33 (0)1 43 78 15 94
Bioquell Asia Pacific Pte Ltd
T: +65 6592 5145
203/10