Bioquell | Z-2 - Labotal.co.il

Hydrogen peroxide vapour (HPV) technology
HPV concentration
t=0*
1
2
3
Inactivation of micro-organisms
GASSING DWELL AERATION
TIME
* Conditioning phase not shown (vaporiser reaches temperature)
Note: “features” on graph change e.g. depending on size of
chamber (& related temperature effect)
4
5
Schematic of Bioquell HPV concentration/time graph
1. HPV introduced – initial rapid increase in HPV concentration
2. HPV saturation/“dew point” achieved – onset of rapid bio-decontamination
3. HPV gassing plateau – sustained micro-condensation effecting bio-deactivation
4. Dwell period (contact time)
5. Aeration – removal of HPV from the atmosphere typically by catalytic
conversion to water vapour and oxygen, leaving no residues
Schematic of dew point and Bioquell kill dynamics
1. Injection of HPV into the enclosure starts (t=0)
2. Only slight decline in biological indicator population prior to dew point
3. Rapid micro-biological kill occurs immediately after saturation/“dew point” is achieved –
process optimised to achieve reliable 6-log sporicidal reduction on all exposed surfaces
4. Onset of micro-condensation correlates with rapid bio-deactivation
5. Bio-deactivation achieved via micro-condensation (invisible layer) of hydrogen
peroxide (2-6µm)
* Typical BI: Tyvek ® pouched 6-log
Geobacillus stearothermophilus spores
Key benefits of HPV
• Excellent material compatibility
including sensitive electronics
• Environmentally friendly –
“residue-free” (breaks down to
water vapour and oxygen)
• Effective against a wide range
of micro-organisms
• High level disinfection achieved
(6-log sporicidal reduction)
• Low temperature
bio-decontamination process
HPV applications
• GMP cleanrooms
• Aseptic processing
• Biologics
• Biomedical
• Biosafety/security
Key features and benefits of the Bioquell Z-2
FEATURES
Unique Bioquell parametric control algorithm
Complete system incorporating gas distribution
and catalytic aeration
Fast, high capacity HPV vaporiser
Fully compliant with GMP requirements
Mobile system
BENEFITS
Fast, efficient cycles with no need for gas cycle
development
Single system HPV for the complete
bio-decontamination process
Quick bio-decontamination of volumes up to 250m 3 , using parametric
control (larger areas can be validated using timed cycles)
Able to be used in regulated areas (if used with
timed HPV cycles)
Can be easily moved to areas requiring
bio-decontamination