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251 286 - Biotech Bayern

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siRion GmbH<br />

BIOTECH DEVICES & REAGENTS<br />

SIRION’s expertise comprises services for RNAi expression and solutions for<br />

customized gene expression. In virtually any cell type, SiRIONs newly developed<br />

QSTEP technology allows for optimal knock down efficiency, which means<br />

also cells resistant to transfection. By means of the proprietary viral QSTEP technology,<br />

the limitations of conventional siRNA transfection are eliminated.<br />

When using QSTEP frozen cells, no time consuming and tedious optimization of<br />

transfection protocols, which give little reproducible results, are needed. QSTEP<br />

guaranties high reproducibility, reliability and optimal knock down efficiencies<br />

for our customer’s assays.<br />

Sloning BioTechnology GmbH<br />

BIOTECH DEVICES & REAGENTS<br />

Keywords: Automation, Genomics, PCR, Proteomics<br />

Sloning BioTechnology GmbH is a <strong>Biotech</strong> company in the vicinity of Munich,<br />

Germany, which has developed a novel way of synthesising double-stranded<br />

DNA molecules (gene constructs). Based on a library of standardised, doublestranded<br />

building blocks, gene constructs are synthesised on a fully automated<br />

robotic platform. Purely research driven in the past, the company has succesfully<br />

entered the market in 2006 as a service provider of customised genes and high<br />

quality SlonoMax mutant libraries.<br />

Sloning's mission is to industrialise the synthesis of artificial genes to unlock<br />

the huge potential of genome data for drug development and production<br />

applications.<br />

SpheroTec GmbH<br />

BIOTECH PRECLINICAL SERVICES<br />

Keywords: Drug Development, Oncology, Tissue Engineering / Cell Culture<br />

SpheroTec means Spherotechnology. Spheroids are miniature tumors in vitro<br />

mimicking microtumors in cancer patients. The three-dimensional tissue like<br />

model allows predictive drug testing with respect to efficacy, cell toxicity,<br />

drug penetration into the microtumor and pharmakodynamic in a very early<br />

preclinical phase of drug development. The advantages are obvious: early<br />

identification of ineffective and highly toxic drugs, effective selection of therapeutically<br />

relevant drugs, high probability of success in advanced clinical trials<br />

and thus FDA approval as well as reduction of animal experiments, time and<br />

costs. The Spherotechnology is appropriate for all kind of drugs including antibodies<br />

and small molecules.<br />

Contact:<br />

Dr. Lars Behrend<br />

Am Klopferspitz 19<br />

D-82152 Martinsried<br />

Phone: +49 (0) 89 7009619-99<br />

Fax: +49 (0) 89 7009619-98<br />

E-Mail: info@sirion-biotech.de<br />

Internet: www.sirion-biotech.de<br />

Contact:<br />

Sascha Meyer<br />

Zeppelinstr. 4<br />

D-82178 Puchheim<br />

Phone: +49 (0) 89 809095-0<br />

Fax: +49 (0) 89 809095-50<br />

E-Mail: info@sloning.de<br />

Internet: www.sloning.com<br />

Contact:<br />

Dr. Barbara Mayer<br />

Am Klopferspitz 19<br />

D-82152 Martinsried<br />

Phone: +49 (0) 89 7095-6438<br />

Fax: +49 (0) 89 7095-6263<br />

E-Mail: bmayer@spherotec.com<br />

Internet: www.spherotec.com<br />

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