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251 286 - Biotech Bayern

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Multimetrix GmbH<br />

BIOTECH DNA/PROTEIN ANALYTICS<br />

Keywords: Clinical Diagnostics, Chip / Array Technology, Autoimmune Diseases,<br />

Clinical Research<br />

Multimetrix's major field of expertise is based on the Luminex technology. This<br />

technology allows the simultaneous quantitative measurement of up to one<br />

hundred different parameters in a single drop of a liquid sample. At the same<br />

time it saves time and money even when compared to a single parameter<br />

measurement using conventional methods. Due to its high flexibility the<br />

Luminex technology can be used to measure all kinds of different analytes that<br />

are characterized by specific binding of two defined molecular interaction<br />

partners, e.g. antigens and antibodies, enzymes and substrates, receptors and<br />

ligands and complementary nucleic acids. The Luminex technology is particularly<br />

suitable for high-throughput applications in the fields of laboratory diagnostics,<br />

pharmacological screening, expression profiling and SNP analysis.<br />

The advantages of the Luminex technology as compared to conventional assay<br />

systems such as ELISA and Western blotting are obvious: it is fully automated,<br />

smaller sample volumes are needed and it provides higher sensitivity and<br />

specificity at a lower price.<br />

Multimetrix develops multiplex test systems for applications in the fields of<br />

diagnostics, pharmacological screening and quality control.<br />

Multimetrix offers the assay development on demand including all required<br />

validation and quality assurance procedures as well as a testing service for<br />

detection of multiple analytes on customer request.<br />

multimmune GmbH, c/o Strahlentherapie<br />

der TU München<br />

BIOTECH THERAPEUTICS & DIAGNOSTICS<br />

Keywords: Drug Development, Clinical Diagnostics, Antibody, Cell Therapy,<br />

Vaccines, Oncology<br />

multimmune is a biopharmaceutical company dedicated to the discovery and<br />

development of new products for the treatment of cancer. The company<br />

focuses on the development of drug candidates to treat heat shock protein 70<br />

(Hsp70) positive tumors, as surface-bound Hsp70 is a tumor-specific marker<br />

expressed on about 50-75% of various cancer entities, e.g. lung, breast, colon,<br />

pancreas.<br />

Currently, four approaches are being explored to destroy cancer cells:<br />

(1) by extracorporal activation of Natural Killer (NK) cells with a synthetic peptide<br />

(ready to go into phase II), (2) by using an antibody against Hsp70 (preclinical),<br />

(3) by direct infusion of an Hsp70 peptide (R&D), (4) by<br />

inducing tumor specific apoptosis with a serine protease(R&D).<br />

Contact:<br />

Dipl.-Biol. Elisabeth Dove<br />

Josef-Engert-Str. 9<br />

D-93053 Regensburg<br />

Phone: +49 (0) 941 30 74 386<br />

Fax: +49 (0) 941 30 74 798<br />

E-Mail: info@multimetrix.com<br />

Internet: www.multimetrix.com<br />

Contact:<br />

Dr. Claus Botzler<br />

Ismaninger Str. 22<br />

D-81675 München<br />

Phone: +49 (0) 89 4140-4298<br />

Fax: +49 (0) 89 4140-4299<br />

E-Mail: info@multimmune.de<br />

Internet: www.multimmune.de<br />

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