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251 286 - Biotech Bayern

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Contact:<br />

Silvia Schmidt<br />

Hanauerstr. 1<br />

D-80992 München<br />

Phone: +49 (0) 89 149096 1600<br />

Fax: +49 (0) 89 149096 2000<br />

E-Mail: silvia.schmidt@amgen.com<br />

Internet: www.onkologie.de<br />

Contact:<br />

Gabriele Wilde<br />

Josef-Engert-Str. 9<br />

D-93053 Regensburg<br />

Phone: +49 (0) 941 465-20000<br />

Fax: +49 (0) 941 465-20100<br />

E-Mail: gwilde@amgen.com<br />

Internet: www.amgen.de<br />

Contact:<br />

Dr. Lars Wassill<br />

Werkstr. 2<br />

D-83555 Gars-Bahnhof<br />

Phone: +49 (0) 8073 91693-0<br />

Fax: +49 (0) 8073 91693-33<br />

E-Mail: info@amplexdiagnostics.de<br />

Internet: www.amplexdiagnostics.de<br />

40<br />

AMGEN GmbH<br />

BIOTECH THERAPEUTICS & DIAGNOSTICS<br />

Keywords: Drug Development<br />

Amgen's corporate mission is to be the world leader in developing and<br />

delivering important, cost-effective therapeutics based on cellular and molecular<br />

biology. The company's first product, EPOGEN® (Epoetin alfa), stimulates<br />

and regulates the production of red blood cells. Amgen's second product,<br />

NEUPOGEN® (Filgrastim), is a recombinant granulocyte colony-stimulating factor<br />

(G-CSF) that selectively stimulates growth of infection-fighting white blood cells<br />

known as neutrophils. In 2001 Amgen launched a new drug, called Aranesp®,<br />

which also stimulates the production of red blood cells. Aranesp® was created<br />

by rational drug design and has a threefold longer halflife time compared to<br />

Epogen®. In 2002 AMGEN launched a second generation G-CSF called Neulasta®<br />

which also stimulates the growth of neutrophils. Neulasta® has an important<br />

advantage. Due to its pegylation Neulasta® has a longer half-life time and<br />

therefore has to be administered only once per chemotherapy cycle whereas<br />

Neupogen® has to be administered daily.<br />

Amgen Research GmbH<br />

PHARMA & CHEMICAL INDUSTRY<br />

Keywords: Drug Development, Small Molecules, Diabetics, Hematology,<br />

Inflammation, Neurology, Oncology<br />

AMGEN, (Applied Molecular Genetics Inc.) was founded in 1980 as one of the<br />

pioneers of industrial biotechnology. The company develops, produces and<br />

sells biopharmaceutical products that are produced through recombinant DNA<br />

technologies. AMGEN Research GmbH was founded in Regensburg in 2000.<br />

Basic research is conducted with the aim of identifying new pharmaceutical lead<br />

structures for the development of innovative drugs. Low molecular weight<br />

compounds are identified by high throughput screening (HTS) procedures. Over<br />

10 million compounds are analyzed every year.<br />

AmplexDiagnostics GmbH – Gesellschaft für<br />

molekularbiologische Diagnostik<br />

BIOTECH DNA/PROTEIN ANALYTICS<br />

Keywords: Clinical Diagnostics, PCR, Infectious Diseases<br />

AmplexDiagnostics GmbH is a privately held company for the development and<br />

production of In Vitro Diagnostics. Our aim is the improvement of the potential<br />

of the PCR-technology by implementing the main advantages of this technology<br />

into the diagnosis of bacterial infections. Founded in 2002 – Amplex developed<br />

its first product (hyplex StaphyloResist) and entered the market already in 2003.<br />

Additional systems (hyplex STD ID for detection of sexually transmitted mycoplasms;<br />

hyplex EHEC for detection of EHEC/EPEC and hyplex EnteroResist for characterisation<br />

of VRE) followed in 2006. Additionally, we developed the first PCR-system<br />

(hyplex ESBL ID) for the direct detection of ESBL producing bacteria direct from<br />

patient material. For further information please visit www.hyplex.info or contact us.

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