Aposense Pipeline: From Platform to Products
Aposense Pipeline: From Platform to Products
Aposense Pipeline: From Platform to Products
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ATT-GEM<br />
Initial in-vivo performance data in responding (sensitive) tumor<br />
(HCT116 colon carcinoma)<br />
Similar efficacy in responsive tumors, with safety benefit<br />
Weight (% of control)<br />
Tumor growth inhibition<br />
115<br />
2000<br />
Control<br />
110<br />
105<br />
100<br />
1800<br />
1600<br />
1400<br />
1200<br />
Gemcitabine 50mg<br />
Gemcitabine 100mg<br />
ATT-GEM1 120mg<br />
ATT-GEM2 120mg<br />
95<br />
1000<br />
800<br />
90<br />
600<br />
85<br />
400<br />
80<br />
0 5 10 15 20 25 30<br />
200<br />
0<br />
0 5 10 15 20 25 30
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