Challenges and Caveats in Oncology Forecasting - Kantar Health
Challenges and Caveats in Oncology Forecasting - Kantar Health
Challenges and Caveats in Oncology Forecasting - Kantar Health
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Biomarkers <strong>and</strong> targeted<br />
therapies are both<br />
largely present <strong>in</strong> the<br />
oncology marketplace,<br />
<strong>and</strong> have the potential<br />
to significantly impact<br />
pharma revenue.<br />
Question 4: As biomarkers <strong>and</strong><br />
targeted therapies cont<strong>in</strong>ue to grow<br />
<strong>in</strong> the oncology market, how is<br />
revenue <strong>in</strong> pharma impacted?<br />
Application of biomarkers has the potential to<br />
significantly benefit revenue <strong>in</strong> pharma, <strong>and</strong> also<br />
presents valid advantages to the development<br />
<strong>and</strong> market<strong>in</strong>g of oncology products. Biomarkers<br />
can be an important factor <strong>in</strong> the approval of<br />
new drugs, enabl<strong>in</strong>g access to <strong>in</strong>dications <strong>and</strong><br />
markets that are otherwise difficult to reach. They<br />
can improve outcomes <strong>in</strong> patient selection.<br />
<strong>and</strong> long durations of therapy for respective<br />
oncology products, <strong>and</strong> good biomarker tests<br />
generally qualify for reimbursement.<br />
The <strong>in</strong>creas<strong>in</strong>g use of targeted therapies has the<br />
potential to reshape the oncology market over<br />
the next few years, chang<strong>in</strong>g cancer treatment<br />
from acute to chronic. In 2013 targeted therapies<br />
represented over 70% of the global market for<br />
oncology drugs. 1 This <strong>in</strong>creased presence also<br />
poses an uncerta<strong>in</strong>ty to the forecasted oncology<br />
market, precipitated by complications <strong>in</strong> duration<br />
of therapy.<br />
Early identification of validated biomarkers, prior<br />
to Phase III, can reduce development costs<br />
<strong>and</strong> expedite product launch. Us<strong>in</strong>g biomarker<br />
selection, it is likely for effective drugs <strong>in</strong> refractory<br />
sett<strong>in</strong>gs to advance to first l<strong>in</strong>e <strong>in</strong> biomarkerdef<strong>in</strong>ed<br />
populations. Biomarkers with good<br />
predictive value may facilitate premium pric<strong>in</strong>g<br />
Sources<br />
1. Company <strong>and</strong> Analyst Reports, Sales estimates<br />
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