The action potential and the underlying ionic currents

Wu et al, Heart Rhythm, 2008, 5(12):1726-34
The fast sodium channel (I Na )
I Na
50 mV
100 ms
outside
Resting state
Na
+
+
Na
outside
Active state
Na
+
+
Na
outside
Inactive state
+
Na
m
m
m
inside -
h
inside -
h
inside
Na
+
h
+