The action potential and the underlying ionic currents
The action potential and the underlying ionic currents
The action potential and the underlying ionic currents
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IMPULSE CONDUCTION<br />
Direction of <strong>the</strong> impulse propagation<br />
1. <strong>The</strong> speed of depolarization (V max )<br />
- depends on fast sodium current<br />
2. Action <strong>potential</strong> amplitude<br />
- depends on fast sodium current<br />
3. Treshold of activation<br />
- depends on fast sodium current<br />
Velocity at which each domino falls<br />
Height of <strong>the</strong> domino<br />
<strong>The</strong> energy needed to push <strong>the</strong> domino<br />
4. <strong>The</strong> cells internal resistance / <strong>the</strong> resistance<br />
between <strong>the</strong> cells (r i )<br />
- depends on <strong>the</strong> gap junctions<br />
What is <strong>the</strong> medium resistance<br />
(water, air, vacuum)<br />
Sodium channels (atria, ventricle) or calcium channels (sinus <strong>and</strong> AV- node)
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