The action potential and the underlying ionic currents
The action potential and the underlying ionic currents
The action potential and the underlying ionic currents
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Cl - Channels Regulated by Cell Volume (I Cl.vol )<br />
Volume-regulated anion channels are now known to be ubiquitously expressed<br />
in mammalian cells <strong>and</strong> play an important role in cell volume homeostasis.<br />
An increase in cell volume activates outwardly rectifying chloride channel,<br />
which inactivate at positive membrane <strong>potential</strong>s.<br />
Exposure to hypotonic solutions is <strong>the</strong> most common technique used to swell cells <strong>and</strong><br />
activate I Cl.vol<br />
Current sensitive to SIDS <strong>and</strong> 9-AC.<br />
Exists also a basally active current
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