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Safety Data Sheet - ProZyme

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<strong>Safety</strong> <strong>Data</strong> <strong>Sheet</strong><br />

1:Identification of substance / mixture<br />

1. Product Identifier<br />

Product Name<br />

5x 2-AB Sample Load Solution<br />

Product Code<br />

WS0303<br />

CAS Number<br />

NA<br />

Other Names<br />

IUPAC<br />

NA<br />

MFCD Number<br />

NA<br />

EC/EINECS<br />

NA<br />

REACH Number<br />

NA<br />

2. Relevant identified uses of the substance or mixture and uses advised against<br />

Research and Development<br />

Mixture<br />

3. Details of the supplier of the safety data sheet<br />

<strong>ProZyme</strong>, Inc<br />

3832 Bay Center Place,<br />

Hayward<br />

CA<br />

Telephone:<br />

94545-3619<br />

Fax number:<br />

USA<br />

Email:<br />

4. Emergency telephone number<br />

+1 (760) 476 3961<br />

+1 (510) 638-6900<br />

+1 (510) 638 6919<br />

info@prozyme.com<br />

2.Hazards Identification<br />

1. Classification of the substance or mixture<br />

H226 Flam Liq. 3 R10<br />

H335 STOT SE 3a R37, R36/37, R36/37/38, R37/38<br />

* The risk codes have been generated using Annex VII of directive 67/548/EEC. Risk code combinations are not included.<br />

2. Label elements<br />

Signal Word Warning<br />

Hazard Statements<br />

H226<br />

H335<br />

Precautionary Phrases<br />

P210<br />

3. Other Hazards<br />

Additional precautionary phrases are located throughout the safety data sheet<br />

3.Composition / Information on Ingredients<br />

1. Substances<br />

Not Relevant<br />

Flammable liquid and vapour.<br />

May cause respiratory irritation.<br />

Keep away from heat/sparks/open flames/hot surfaces. – No smoking.<br />

2. Mixtures: There are no additional ingredients present which, within the current knowledge of the supplier and in the<br />

concentrations applicable,are classified as hazardous to health or the environment and hence require reporting in this<br />

section.<br />

Rev AB Revision Date: 28 May 2013<br />

Page 1 of 7


<strong>Safety</strong> <strong>Data</strong> <strong>Sheet</strong><br />

Concentration Product Name CAS Number EC/EINECS<br />

60-90% Dimethyl Sulfoxide 67-68-5 200-664-3<br />

< 2% Trifluoroacetic Acid 73-05-1 200-929-3<br />

4.First Aid Measures<br />

1.Description of first aid measures<br />

Skin Contact Wash immediately with plenty of soap and water. If symptoms arise, consult a physician.<br />

Eye Contact<br />

Ingestion<br />

Inhalation<br />

Rinse with plenty of water for 15 minutes. If symptoms arise, consult a physician.<br />

Wash out mouth with water. Never give anything by mouth to an unconscious person. If symptoms arise,<br />

consult a physician. Do not induce vomiting without medical advice.<br />

P304 + P340: IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing.<br />

If symptoms arise, call a physician. If not breathing, give artificial respiration.<br />

2.Most important symptoms and effects<br />

May be harmful if swallowed, inhaled or absorbed through the skin. May cause irritation to skin, eyes and respiratory tract.<br />

3.Indication of any immediate medical attention<br />

Obtain medical attention in the event of any acute or delayed symptoms.<br />

5.Firefighting measures<br />

1.Extinguishing Media<br />

Suitable<br />

Unsuitable<br />

For small (incipient) fires, use media such as "alcohol" foam, dry chemical, or carbon dioxide. For large fires,<br />

apply water from as far as possible.<br />

NA<br />

2.Special Hazards arising from the substance or mixture<br />

Combustible. Moderate fire hazard when exposed to heat or flame (fire data for dimethyl sulfoxide).<br />

3.Advice for Fire Fighters<br />

Wear self-contained breathing apparatus and protective clothing for firefighting. Use water spray to cool unopened containers.<br />

6.Accidental Release Measures<br />

1.Personnal Precautions<br />

Avoid breathing vapors, mist or gas. Refer to section 8 of SDS for personal protection details.<br />

2.Environmental Precautions<br />

Prevent further leakage or spillage if safe to do so. Do not let product enter drains or rivers.<br />

3.Methods & Materials<br />

Remove all sources of ignition. Beware of vapours accumulating to form explosive concentrations. Vapours can accumulate in low<br />

areas. Contain spillage and neutralize with alkaline material (soda ash, lime), then absorb with an inert material (e.g. vermiculite,<br />

dry sand, earth), and place in a chemical waste container for disposal according to local regulations. Do not use combustible<br />

materials. Do not flush to sewer.<br />

Page 2 of 7


<strong>Safety</strong> <strong>Data</strong> <strong>Sheet</strong><br />

7.Handling and Storage<br />

1.Personnal Precautions<br />

Safe Handling<br />

Protection against<br />

explosions and fires<br />

Use personal protective equipment. Avoid inhalation of vapour or mist.<br />

Keep away from sources of heat or ignition.<br />

2.Conditions for safe storage, including any incompatibilities<br />

Managing Storage Risks<br />

Storage Controls<br />

Maintaining Integrity<br />

Other advice<br />

Keep container tightly closed in a dry and well-ventilated place. Protect from physical damage.<br />

Store according to product labeling.<br />

P210: Keep away from heat/sparks/open flames/hot surfaces. – No smoking.<br />

P233: Keep container tightly closed.<br />

Store at room temperature.<br />

Handle and store in accordance with all current regulations and standards.<br />

3.Specific End Uses<br />

The end use(s) have not been fully determined. The substance is supplied for Research and Development purposes by<br />

professionals only.<br />

8.Exposure Controls/Personal Protection<br />

1. Control Parameters<br />

Not Applicable<br />

2.Exposure Controls<br />

General protective and<br />

hydgiene measures<br />

Engineering measures<br />

Eye / Face Protection<br />

Hand protection<br />

Respiratory protection<br />

Skin protection<br />

Other personal protection<br />

advice<br />

P280: Wear protective gloves/protective clothing/eye protection/face protection.<br />

Ensure there is sufficient ventilation of the area.<br />

<strong>Safety</strong> Glasses with side-shields.<br />

Protective gloves such as nitrile.<br />

P261: Avoid breathing dust/fume/gas/mist/vapours/spray.<br />

Where risk assessment shows air-purifying respirators are appropriate use a full-face respirator with<br />

multi-purpose combination (US) or type ABEK (EN 14387) respirator cartridges as a backup to<br />

engineering controls. If the respirator is the sole means of protection, use a full-face supplied air<br />

respirator. Use respirators and components tested and approved under appropriate government<br />

standards such as NIOSH (US) or CEN (EU).<br />

Wear appropriate protective clothing (safety glasses, gloves, laboratory coat).<br />

NA<br />

9.Physical and Chemical Properties<br />

1. Physical and Chemical Properties<br />

Appearance<br />

Odour<br />

Odour threshold<br />

PH<br />

Melting point / Freezing point<br />

Initial boiling point and boiling range<br />

Flash point<br />

Evaporation rate<br />

Clear, colorless<br />

Pungent odor<br />

Not Applicable<br />

Not Applicable<br />

Not Applicable<br />

Not Applicable<br />

Not Applicable<br />

Not Applicable<br />

Page 3 of 7


<strong>Safety</strong> <strong>Data</strong> <strong>Sheet</strong><br />

Flammability(solid,gas)<br />

Upper/lower flammability or explosive limits<br />

Vapour pressure<br />

Vapour density<br />

Relative density<br />

Solubility(ies):<br />

Partition coefficient: n-octanol/water<br />

Auto-ignition temperature<br />

Decomposition temperature<br />

Viscosity<br />

Explosive properties<br />

Oxidising properties<br />

Not Applicable<br />

Not Applicable<br />

Not Applicable<br />

Not Applicable<br />

Not Applicable<br />

Miscible in water<br />

Not Applicable<br />

Not Applicable<br />

Not Applicable<br />

Not Applicable<br />

Not Applicable<br />

Not Applicable<br />

2.Other Information<br />

NA<br />

10.Stability and Reactivity<br />

1.Reactivity<br />

No dangerous reaction known under conditions of normal use.<br />

2.Stability<br />

Stable under recommended storage conditions.<br />

3.Possibility of Hazardous Reactions<br />

No hazardous reactions known.<br />

4.Conditions to Avoid<br />

Sources of ignition, heat, flames and incompatibles.<br />

5.Incompatible Materials<br />

Acylhalides, arylhalides, bromobenzoyl acetanilide, magnesium perchlorate, perchloric acid, strong bases, strong oxidizing agents<br />

and strong reducing agents.<br />

6.Hazardous Decomposition Products<br />

Hazardous decomposition products formed under fire conditions: Carbon oxides, sulphur oxides, formaldehyde, methyl mercaptan<br />

and hydrogen fluoride.<br />

Other decomposition products - no data available<br />

11.Toxicology information<br />

1.Information<br />

Acute Toxicity<br />

Skin corrosion/irritation<br />

DMSO: Oral LD50 - rat - 14,500 mg/kg<br />

Trifluoroacetic Acid: Oral LD50 - rat - 200-400 mg/kg<br />

May be harmful if absorbed through the skin. May cause skin irritation.<br />

Serious eye<br />

Damage/irratation<br />

Respiratory or skin<br />

sensitisation<br />

Germ Cell mutagenicity<br />

Carcinogenicity<br />

Reproductive toxicity<br />

STOT-single exposure<br />

May cause eye irritation.<br />

May be harmful if inhaled.<br />

No data available.<br />

No data available.<br />

DMSO: No data available.<br />

TFA: Undiluted TFA has shown reproductive toxicity effects on laboratory animals.<br />

No data available.<br />

Page 4 of 7


<strong>Safety</strong> <strong>Data</strong> <strong>Sheet</strong><br />

STOT-repeated exposure<br />

Aspiration hazard<br />

2.Additional<br />

No data available.<br />

May be harmful if inhaled.<br />

To the best of our knowledge, the toxicological, carcinogenic and mutagenic properties have not been thoroughly investigated.<br />

DMSO: Avoid contact with solutions containing toxic or potentially toxic materials. DMSO is readily absorbed through the skin and<br />

may carry such materials into the body.<br />

12.Ecological Information<br />

1.Toxicity<br />

No data available.<br />

2.Persistance and degradability<br />

Difficult to biodegrade.<br />

3.Bio-Accumulative Potential<br />

This material is not expected to significantly bioaccumulate.<br />

4.Mobility and Soil<br />

No data available.<br />

5.Results of PBT & vPvB assessment<br />

No data available.<br />

6.Other adverse effects<br />

No data available.<br />

13.Disposal Considerations<br />

1.Waste Treatment Methods<br />

Disposal Operations<br />

Disposal of Packaging<br />

Whatever cannot be saved for recovery or recycling should be managed in an appropriate and<br />

approved hazardous waste disposal facility. Dispose of container and unused contents in accordance<br />

with federal, state and local requirements.<br />

Dispose of as unused product.<br />

14. Transport Information<br />

Air (ICAO)<br />

Not classified as hazardous for transport<br />

Road (ADR)<br />

Not classified as hazardous for transport<br />

Sea (IMDG)<br />

Not classified as hazardous for transport<br />

Page 5 of 7


15.<strong>Safety</strong>, health and environmental regulations<br />

1.<strong>Safety</strong>, health and environmental regulations:<br />

OSHA Hazards<br />

Combustible Liquid<br />

TSCA Listing<br />

Dimethylsulfoxide (67-68-5) Yes<br />

Trifluoroacetic Acid (76-05-1) Yes<br />

SARA 302 Components<br />

SARA 302: No chemicals in this material are subject to the reporting requirements of SARA Title III, Section 302.<br />

SARA 313 Components<br />

SARA 313: This material does not contain any chemical components with known CAS numbers that exceed the threshold (De<br />

Minimis) reporting levels established by SARA Title III, Section 313.<br />

SARA 311/312 Hazards<br />

Fire Hazard, Chronic Health Hazardldrich - W387509 Page 7 of 7<br />

Massachusetts Right To Know Components<br />

No components are subject to the Massachusetts Right to Know Act.<br />

Pennsylvania Right To Know Components<br />

Dimethyl sulfoxide (67-68-5) Revision Date: 2007-03-01<br />

New Jersey Right To Know Components<br />

Dimethyl sulfoxide (67-68-5) Revision Date: 2007-03-01<br />

California Prop. 65 Components<br />

This product does not contain any chemicals known to State of California to cause cancer, birth defects, or any other<br />

reproductive harm.<br />

2. <strong>Safety</strong> Assessment<br />

No Chemical <strong>Safety</strong> Assessment<br />

16.Other Information<br />

1.Other Information:<br />

ADR: Accord Europeen sur le transport des merchandises Dangereuses par Route(European Agreement concerning the<br />

International Carriage of Dangerous Goods by road)<br />

RID:Reglement International concernant le transport des merchandises dangereuses par chemin de fer (Regulations concerning the<br />

International transport of Dangerous Goods by Rail)<br />

IMDG: International Maritime Code for Dangerous Goods<br />

IATA: International Air Transport Association<br />

IATA-DGR: Dangerous Goods Regulations by the International Air Transport Association<br />

ICAO:International Civil Aviation Organization<br />

ICAO-TI: Technical Instructions by the ICAO<br />

GHS: Globally Harmonized System of Classification and Labelling of Chemicals<br />

CAS:Chemical Abstracts Service<br />

R10<br />

Flammable.<br />

R36/37 Irritating to eyes and respiratory system.<br />

R36/37/38<br />

R37<br />

Irritating to eyes, respiratory system and skin.<br />

Irritating to respiratory system.<br />

R37/38 Irritating to respiratory system and skin.<br />

<strong>Safety</strong> <strong>Data</strong> <strong>Sheet</strong><br />

2. Associated risk phrases according to european directive 67/548/EEC<br />

3. Disclaimer<br />

Page 6 of 7


<strong>Safety</strong> <strong>Data</strong> <strong>Sheet</strong><br />

The product listed is for research and development purposes only and not for human or animal use. As such, in most cases, the<br />

toxicological, ecological and physicochemical properties have not been fully determined and the product should be treated with<br />

respect and always handled under suitable conditions by appropriately qualified personnel. The responsible party shall use this<br />

datasheet only in conjunction with other sources of information gathered by them, and should make an independent judgement of<br />

suitability, to ensure proper use and protect the health and safety of employees. This information is furnished without warranty and<br />

any use of the product not in conformance with this material safety data sheet, or in combination with any other product or process,<br />

is the responsibility of the user.<br />

The above information is supplied in good faith and is believed to be correct. It does not claim to be all-inclusive and is intended to<br />

be used only as a guide. Final determination of the suitability of any material is the sole responsibility of the user. <strong>ProZyme</strong> shall<br />

not be held responsible for any damage resulting from handling or contact with the above product. This product is intended for in<br />

vitro research only.<br />

Page 7 of 7

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