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BG's Wake Up Call - Bryan, Garnier & Co

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25th March 2013<br />

BG’s <strong>Wake</strong> <strong>Up</strong> <strong>Call</strong><br />

Please find our Research on Bloomberg BRYG )<br />

Last<br />

close<br />

Daily chg<br />

(%)<br />

Chg YTD<br />

(%)<br />

Indices<br />

Dow Jones 14512.03 +0.63% +10.74%<br />

S&P 500 1556.89 +0.72% +9.16%<br />

Nasdaq 3245 +0.70% +7.47%<br />

Nikkei 12546.46 +1.69% +18.69%<br />

Stoxx 600 294.038 -0.15% +5.14%<br />

CAC 40 3770.29 -0.12% +3.55%<br />

Oil /Gold<br />

Crude WTI 93.39 +1.46% +1.64%<br />

Gold (once) 1608.38 -0.35% -3.25%<br />

Currencies/Rates<br />

EUR/USD 1.2997 +0.55% -1.42%<br />

EUR/CHF 1.222 -0.02% +1.26%<br />

German 10 years 1.372 0.00 +5.62%<br />

French 10 years 2.013 +0.29% +1.15%<br />

Euribor 0.215 +1.90% +14.97%<br />

Economic releases :<br />

Date<br />

25th-Mar US - Ben Bernanke speaks<br />

US - Dallas fed manufacturing survey (3.4<br />

exp.)<br />

IT - <strong>Co</strong>nsumer confidence Index Mar. (85.5<br />

exp.)<br />

<strong>Up</strong>coming BG events :<br />

Date<br />

18th-Apr<br />

Recent reports :<br />

Date<br />

21st-Mar<br />

20th-Mar<br />

8th-Mar<br />

8th-Mar<br />

7th-Mar<br />

6th-Mar<br />

300<br />

290<br />

280<br />

270<br />

260<br />

Nuclear - <strong>Co</strong>sts & Financial risks (BG Paris Lunch<br />

with B. Dessus)<br />

Pennon Group (BUY, FV 800p) The benefits of<br />

inflation!<br />

Grifols (Buy, FV EUR31 vs. 29.5) Don't forget<br />

Alzheimer's<br />

Adocia (<strong>Co</strong>rporate, FV EUR19.5) An ally of choice in<br />

diabetes<br />

Roche (Neutral, FV CHF208) GA-101 holds the keys<br />

to the CD20 franchise<br />

Sorin (Buy, FV EUR2.4) 2013 : a decisive year for<br />

M&A ?<br />

Veolia Environnement (Buy, FV EUR13) Roadshow<br />

25/3/13<br />

TEMENOS GROUP BUY, Fair Value CHF26 vs. CHF24 (+20%)<br />

TriNovus acquisition conference call feedback: the US opportunity<br />

We reiterate our Buy rating and increase our DCF-derived fair value to CHF26 from<br />

CHF24, as we increase our medium-term sales lfl growth assumption (+11% vs. +10%)<br />

following last Friday’s conference call regarding the acquisition of TriNovus. We estimate<br />

that, altogether, the renewal of T24 10-year licences and the acquisition of TriNovus will<br />

add respectively 2%, 3% and 5% to our sales projections for 2013, 2014 and 2015. We<br />

also expect the deal will have a neutral impact to our 2013 adj. EPS est. but will be<br />

accretive by respectively 1% and 3% for 2014 and 2015.<br />

ASTRAZENECA BUY, Fair Value 3540p vs. 3400p (+9%)<br />

2018 substantially too low, 2013 potentially the bottom<br />

As we said several times before it took place, last week’s Investors Day had two<br />

objectives: 1) to restore confidence over the medium to long term which was pretty<br />

much dependent on the quality of the teams at work and the ability of R&D to deliver; 2)<br />

to offer upside to consensus numbers in a not-too-distant future and see whether a<br />

return to growth was by any means possible as early as in 2014. Although the first goal<br />

was in our view more convincingly achieved, the second was deemed achievable but is<br />

not yet granted and will depend on a few parameters including Brilinta and one or two<br />

tailored bolt-on acquisitions.<br />

BUREAU VERITAS BUY, Fair Value EUR125 vs. EUR100 (+29%)<br />

Far from over (full report published today<br />

Following a particularly enviable stockmarket performance, the share's current multiples<br />

could prompt profit-taking moves. However, we believe the share could clearly continue<br />

its uptrend in view of the quality of fundamentals, which justify higher valuation<br />

assumptions in our DCF calculation. On this basis our Fair Value works out to EUR125.<br />

PHARMACEUTICALS<br />

CHMP: MS treatments in the heart of recommendations<br />

Last Friday, two multiple sclerosis drugs were recommended by the CHMP for approval:<br />

Aubagio from Sanofi and Tecfidera (BG-12) from Biogen. The landscape of MS drugs<br />

completely moves from subcutaneous treatments (IFN) to oral treatments. These two<br />

drugs come on the European market in direct competition with interferons such as Rebif<br />

from Merck but also with Gilenya the first oral compound in this pathology.<br />

LUXURY GOODS<br />

Tiffany’s Q4 earnings ahead of estimates and more optimism for 2013<br />

Last Friday Tiffany posted Q4 sales globally in line with market expectations and with<br />

Xmas season (stable at same-store). Despite ongoing poor trends in the U.S., TIF<br />

delivered an upbeat guidance for 2013 (“high-single digit increase”), mainly thanks to<br />

Asia-Pacific that showed some positive signs, leading to an optimistic guidance for 2013<br />

(“mid-teens sales increase”).<br />

In brief...<br />

AXA, Exclusive talks for the potential sale of a majority stake in AXA Private Equity<br />

AXA received an irrevocable offer from an investor group for its entire stake in AXA<br />

Private Equity.<br />

TRANSGENE, An important production deal with Sanofi<br />

Transgene and Sanofi jointly announced this morning an agreement for the production of<br />

immunotherapy products on a newly-created state of the art platform. The industrial site<br />

is located on Genzyme’s polyclonals site in Lyon<br />

250<br />

240<br />

230<br />

M A M J J A S O N D J F M<br />

STOXX EUROPE 600 E - PRICE INDEX


BG’s <strong>Wake</strong> <strong>Up</strong> <strong>Call</strong><br />

Back to front page<br />

IT Software & Services<br />

Temenos Group<br />

TriNovus acquisition conference call feedback: the US opportunity<br />

Price CHF21.70 Fair Value CHF26 vs. CHF24 (+20%) BUY<br />

Bloomberg<br />

TEMN SW<br />

Reuters<br />

TEMN.SW<br />

12-month High / Low (CHF) 21.7 / 10.3<br />

Market Cap (CHF) 1,562<br />

Ev (BG Estimates) (CHF) 1,629<br />

Avg. 6m daily volume (000) 342.5<br />

3y EPS CAGR 30.5%<br />

We reiterate our Buy rating and increase our DCF-derived fair value to CHF26 from CHF24, as we<br />

increase our medium-term sales lfl growth assumption (+11% vs. +10%) following last Friday’s<br />

conference call regarding the acquisition of TriNovus. We estimate that, altogether, the renewal<br />

of T24 10-year licences and the acquisition of TriNovus will add respectively 2%, 3% and 5% to our<br />

sales projections for 2013, 2014 and 2015. We also expect the deal will have a neutral impact to<br />

our 2013 adj. EPS est. but will be accretive by respectively 1% and 3% for 2014 and 2015.<br />

1 M 3 M 6 M 31/12/12<br />

Absolute perf. 8.8% 35.6% 47.1% 35.6%<br />

Softw.& <strong>Co</strong>mp. 2.7% 5.3% 10.6% 5.1%<br />

SVS<br />

DJ Stoxx 600 1.9% 4.7% 6.6% 5.1%<br />

YEnd Dec. (US$m) 2012 2013e 2014e 2015e<br />

Sales 450.2 477.3 522.2 589.0<br />

% change 6.0% 9.4% 12.8%<br />

EBITDA 131 155 180 212<br />

EBIT 48.1 87.9 110.2 139.5<br />

% change 82.7% 25.3% 26.6%<br />

Net income 62.4 94.7 113.4 138.8<br />

% change 51.7% 19.7% 22.4%<br />

2012 2013e 2014e 2015e<br />

Operating margin 21.5 25.2 26.9 28.8<br />

Net margin 5.4 13.6 16.1 18.6<br />

ROE 6.2 15.0 17.3 18.4<br />

ROCE 17.1 20.9 24.8 30.7<br />

Gearing 25.0 16.5 0.6 -20.7<br />

(US$) 2012 2013e 2014e 2015e<br />

EPS 0.79 1.19 1.43 1.75<br />

% change - 51.7% 19.7% 22.4%<br />

P/E 29.3x 19.3x 16.2x 13.2x<br />

FCF yield (%) 1.9% 4.3% 5.7% 7.3%<br />

Dividends (US$) 0.3 0.4 0.5 0.6<br />

Div yield (%) 1.3% 1.7% 2.2% 2.6%<br />

EV/Sales 3.9x 3.6x 3.2x 2.6x<br />

EV/EBITDA 13.4x 11.2x 9.2x 7.3x<br />

EV/EBIT 18.1x 14.4x 11.8x 9.1x<br />

ANALYSIS<br />

• No excessive acquisition price. Temenos expects TriNovus to contribute USD8m to 2013 sales.<br />

TriNovus’s revenue structure is typical of SaaS vendors, i.e. 70-80% in SaaS and 20-30% in<br />

Services. Customers pay for 5-year subscriptions and TriNovus’s USD17m contracted revenues<br />

are due within the next 3-3.5 years. Temenos will pay 1.5x contracted revenues, i.e. c.USD26m,<br />

which represents c.2.6x 2013 est. annualised 2013 revenue, which we estimate at c.USD10m.<br />

Such a multiple is way below the average of listed SaaS vendors (Salesforce.com’s EV/sales<br />

multiple is above 8x).<br />

• Technical integration under way. Temenos has already started the process of integrating its<br />

T24 platform with TriNovus’s services, of which the most important is Tri<strong>Co</strong>mply, which helps<br />

compliance officers to keep abreast of the latest regulatory requirements. What is helping<br />

Temenos to make such integration pretty easy - it is planned to be achieved some time in 2013<br />

- is the fact the pre-packaged US functionality (model bank) already exists as it had been<br />

developed in cooperation with Metavante (purchased by FIS since) between 2007 and 2009.<br />

• How to get to c.USD30-60m sales by 2016? While TriNovus is expected to account for 2% of<br />

sales, Temenos anticipates it would account for 5-10% in under 3 years, i.e. an est. USD30-60m.<br />

This is expected to be achieved through cross-selling between TriNovus’s installed base (800<br />

banks of all sizes, of which 75-80% are based in the Southern part of the US) and Temenoss’<br />

products (T24, BI, Private Wealth, Payments) on a SaaS or hosted mode, and, if the customer<br />

asks for, on premise. This will require some investments in sales and marketing, which should<br />

not prevent TriNovus from increasing margins and reach Temenos’s levels in under 3 years.<br />

Such cross-selling is deemed to significantly increase the average selling price (which is very<br />

low) thanks to Temenos’s products.<br />

• Opportunity to benefit from the consolidation of the US market. The US <strong>Co</strong>re banking<br />

solutions market is dominated by FIS, Fiserv and Jack Henry Associates, who primarily through<br />

their solutions provide transaction processing services with outdated technologies (including<br />

“batch” processing) and multiple inflexible core systems. Given that changing customer<br />

behaviour and new regulations are serious challenges for US banks, there is a chance Temenos<br />

may be successful in dislodging incumbents in some cases as it could be a serious alternative to<br />

them.<br />

VALUATION<br />

• Our new DCF-derived fair value of CHF26 (vs. CHF24) is based on medium-term lfl revenue<br />

growth rate of 11% (vs. 10%) and a medium-term adj. EBIT margin of 29% (vs. 30%).<br />

• Temenos’ shares are trading at est. 14.4x 2013 and 11.8x 2014 EV/EBIT multiples.<br />

• Net debt on 31 st December 2012 was USD96.7m (net gearing: 25%).<br />

NEXT CATALYSTS<br />

• Q1 13 results on 23 rd April before markets open.<br />

• TCF 2013 user conference on 14 th -16 th May in Abu Dhabi (UAE).<br />

Analyst :<br />

Gregory Ramirez<br />

33(0) 1 56 68 75 91<br />

gramirez@bryangarnier.com<br />

25 March 2013 2


BG’s <strong>Wake</strong> <strong>Up</strong> <strong>Call</strong><br />

Back to front page<br />

Healthcare<br />

AstraZeneca<br />

2018 substantially too low, 2013 potentially the bottom<br />

Price 3,236p Fair Value 3540p vs. 3400p (+9%) BUY<br />

Bloomberg<br />

AZN LN<br />

Reuters<br />

AZN.L<br />

12-month High / Low (p) 3,236 / 2,591<br />

Market Cap (GBP) 40,390<br />

Ev (BG Estimates) (GBP) 39,855<br />

Avg. 6m daily volume (000) 2,318<br />

3y EPS CAGR -4.6%<br />

1 M 3 M 6 M 31/12/12<br />

Absolute perf. 9.6% 10.1% 10.0% 11.2%<br />

Healthcare 3.9% 9.5% 10.2% 10.2%<br />

DJ Stoxx 600 1.9% 4.7% 6.6% 5.1%<br />

YEnd Dec. (USDm) 2012 2013e 2014e 2015e<br />

Sales 27,973 26,447 26,693 26,988<br />

% change -5.5% 0.9% 1.1%<br />

EBITDA 10,666 7,791 9,631 9,989<br />

EBIT 8,148 5,141 6,981 7,339<br />

% change -36.9% 35.8% 5.1%<br />

Net income 8,662 6,679 6,992 7,260<br />

% change -22.9% 4.7% 3.8%<br />

2012 2013e 2014e 2015e<br />

Operating margin 29.1 19.4 26.2 27.2<br />

Net margin 22.3 13.6 19.0 20.1<br />

ROE 26.4 15.1 20.8 21.2<br />

ROCE 21.0 13.1 17.8 26.0<br />

Gearing 10.9 0.0 -7.2 -21.1<br />

(USD) 2012 2013e 2014e 2015e<br />

EPS 6.87 5.34 5.70 5.96<br />

% change - -22.2% 6.8% 4.5%<br />

P/E 7.2x 9.2x 8.6x 8.3x<br />

FCF yield (%) 1.9% 9.9% 10.3% 12.1%<br />

Dividends (USD) 2.8 2.8 2.8 2.8<br />

Div yield (%) 5.7% 5.7% 5.7% 5.7%<br />

EV/Sales 2.3x 2.3x 2.2x 2.0x<br />

EV/EBITDA 5.9x 7.8x 6.1x 5.5x<br />

EV/EBIT 7.8x 11.8x 8.4x 7.5x<br />

As we said several times before it took place, last week’s Investors Day had two objectives: 1) to<br />

restore confidence over the medium to long term which was pretty much dependent on the<br />

quality of the teams at work and the ability of R&D to deliver; 2) to offer upside to consensus<br />

numbers in a not-too-distant future and see whether a return to growth was by any means<br />

possible as early as in 2014. Although the first goal was in our view more convincingly achieved,<br />

the second was deemed achievable but is not yet granted and will depend on a few parameters<br />

including Brilinta and one or two tailored bolt-on acquisitions.<br />

ANALYSIS<br />

• What AstraZeneca was very good at during this Investors Day was to convince that something<br />

had already happened within the company that makes it more likely to succeed in the future<br />

compared to its poor track-record, notably in R&D. We met many people that either joined the<br />

company over the last 3 years or are reviving under the new management which includes not<br />

only Pascal Soriot who is the architect we heard a lot of positives about but also other key<br />

leaders like Briggs Morrison (Head of Development and Chief Medical Officer) or previous<br />

MedImmune people. We found the team both enthusiastic and very knowledgeable.<br />

• The various presentations about R&D left us convinced that AstraZeneca has now adjusted and<br />

adapted to the requirements of the science and regulations of the various agencies around the<br />

world. We found many similarities with what was wrong at Sanofi when Chris Viehbacher joined:<br />

complexity, bureaucracy, inability to kill and to select projects, lack of openness to the external<br />

world, mistrust in biology and sequencing, etc … A lot has been turned in the right direction over<br />

the last 2 years and the first fruit should be ready to be picked in the next 2 years. In the oncology<br />

and respiratory fields, AstraZeneca showed very interesting new data which should give rise to<br />

assets which are currently not meaningfully or not at all valued by the Street. On the first hand,<br />

moxetumomab (hairy cell leukaemia), selumetinib (lung cancer) and olaparib (ovarian cancer)<br />

could all start phase III in 2013 and some to go filing with phase II data. On the other hand,<br />

benralizumab (anti-IL5) and tralokinumab (anti-IL13) are fast followers behind GSK and Roche<br />

respectively whereas AZD2115 and AZD5423 could be respectively first MABA and first SGRM to<br />

market.<br />

• At this stage, there is a dilemma with a company like AstraZeneca, i.e. a pure play where R&D is<br />

facing an upturn which is likely to translate into a re-rating. We are not capturing well the<br />

potential growth ahead because only phase III assets are included into our models. We thus<br />

decided to at least add compounds in late phase III whose proof of concept had previously been<br />

made by competitors: this is true for selumetinib (although not in mutated kras lung cancer,<br />

hence with a POS of only 20%), for benralizumab (POS of 40% vs 50% for mepolizumab at GSK),<br />

for tralokinumab (POS of 20%, equal to Roche’s lebrikizumab) and we are re-introducing<br />

olaparib (only in ovarian cancer) whose data will be presented at ASCO but sound very good<br />

already with a potential filing based on phase II in Europe.<br />

• All those ignored or undervalued assets in R&D form the base of management’s confidence to<br />

“substantially beat the 2018 consensus” of USD21.5bn in revenues. We were around that level<br />

too, mainly because we gave no value to assets prior to phase III.<br />

• Now the second origin for a better-than-expected performance relies on the growth platforms,<br />

o/w Brilinta and emerging markets will play a more significant role. This is where AstraZeneca<br />

has to accelerate to capture more available growth. We are very comfortable with our<br />

assumptions about Brilinta and above consensus numbers although a bit aggressive for 2013. In<br />

emerging markets, we are likely to be too shy but it is always more difficult to reflect<br />

performance as the reporting of sales is product-oriented rather geography-driven. However,<br />

with new manufacturing capacities coming on-stream in India, in China and in Russia, with<br />

increasing support, new products being approved and launched in key segments like COPD,<br />

diabetes and thrombosis, we are not fully appreciating the opportunity of emerging markets for<br />

AstraZeneca. The same is true for Japan where Nexium, Symbicort COPD and Brilinta are huge<br />

opportunities. Just a word on diabetes to say that the excitement is maximum with Forxiga at<br />

AstraZeneca and so this drug will to be carefully monitored. The drug which should be re-filed<br />

in the US by mid-2013 could be approved by year-end. We have a USD600m contribution in<br />

2020 (as a reminder this is a 50% share of gross profits as a consequence of the agreement with<br />

BMS).<br />

• And so in the end, what does that mean for AstraZeneca in 2014 and 2015? When asked<br />

whether there could be a chance for 2013 to be the bottom year, CFO Simon Lowth answered<br />

positively. But it is far from certain. First, AstraZeneca has to make sure it will be able to regain<br />

25 March 2013 3


BG’s <strong>Wake</strong> <strong>Up</strong> <strong>Call</strong><br />

Back to front page<br />

momentum in emerging markets, even more importantly to successfully re-launch Brilinta in<br />

the US. Second, P&L top and bottom lines could not behave in parallel as new cost-cutting<br />

initiatives will deliver significant savings in 2014 and 2015 (USD450m and USD650m<br />

respectively in the two years). Third, in order to be more comfortable with an objective of<br />

stability or growth for the top-line in 2014, AstraZeneca would need one or two business<br />

development initiatives themselves able to translate into immediate extra growth.<br />

VALUATION<br />

• In conclusion, AstraZeneca has set the scenario for the upcoming years. Not all will change in<br />

the short term but we identify different elements that can surprise positively. So, from now on,<br />

either we wait and see and act on facts or we confirm that AstraZeneca is starting on its new<br />

journey and that it is worth jumping on the train sooner rather than later.<br />

• We made various changes to our model, not all positive. We factored in the new restructuring<br />

programmes both in R&D and in SG&A. We included new R&D assets as illustrated above,<br />

although with low POS as of yet. All in all, our new FV stands at 3,540 p which represents a 9%<br />

upside to the current share price without any change to our valuation metrics. Hence we could<br />

have argued that AstraZeneca could deserve a lower specific risk premium (currently 75bp on<br />

top of the equity risk premium) or that a 1% long-term growth rate is too low but we did not<br />

want anything to be seen as artificial. Moreover it is our belief that the re-rating will be gradual<br />

and that part of it will only happen once the company starts delivering on promises. So our<br />

WACC remains at 8.29% i.e. the highest in our universe. Our BUY rating is maintained.<br />

NEXT CATALYSTS<br />

• Q2-2013: phase II data for benralizumab (asthma) and phase III start, phase II data for<br />

tralokinumab (asthma), presentation of phase II data for olaparib in BCRAm ovarian cancer and<br />

selumetinib in KRASm lung cancer at ASCO, phase III start for moxetumomab in hairy cell<br />

leukemia (orphan designation);<br />

• H2-2013: tralokinumab (asthma) phase III start, brodalumab (psoriasis) phase III start, olaparib<br />

filing in Europe in BCRAm ovarian cancer<br />

Two selected charts from AstraZeneca’s pack of slides (Investor Day, March 2013)<br />

Click here to download document<br />

Analyst :<br />

Eric Le Berrigaud<br />

33(0) 1 56 68 75 33<br />

eleberrigaud@bryangarnier.com<br />

Sector Team :<br />

Mathieu Chabert<br />

Martial Descoutures<br />

25 March 2013 4


BG’s <strong>Wake</strong> <strong>Up</strong> <strong>Call</strong><br />

Back to front page<br />

Business Services<br />

Bureau Veritas<br />

Far from over (full report published today<br />

Price EUR97.15 Fair Value EUR125 vs. EUR100 (+29%) BUY<br />

Bloomberg<br />

BVI FP<br />

Reuters<br />

BVI.PA<br />

12-month High / Low (EUR) 100.1 / 64.2<br />

Market Cap (EURm) 10,731<br />

Ev (BG Estimates) (EURm) 11,923<br />

Avg. 6m daily volume (000) 141.5<br />

3y EPS CAGR 12.8%<br />

1 M 3 M 6 M 31/12/12<br />

Absolute perf. 0.5% 14.8% 25.4% 14.8%<br />

Industry 1.9% 4.7% 6.6% 5.1%<br />

DJ Stoxx 600 1.9% 4.7% 6.6% 5.1%<br />

YEnd Dec. (EURm) 2012 2013e 2014e 2015e<br />

Sales 3,903 4,343 4,685 5,084<br />

% change 11.3% 7.9% 8.5%<br />

EBITDA 661 790 871 976<br />

EBIT 639.2 718.4 794.8 885.7<br />

% change 12.4% 10.6% 11.4%<br />

Net income 402.6 459.8 513.1 576.8<br />

% change 14.2% 11.6% 12.4%<br />

2012 2013e 2014e 2015e<br />

Operating margin 16.4 16.5 17.0 17.4<br />

Net margin 10.3 10.6 11.0 11.3<br />

ROE 35.2 33.4 32.0 30.3<br />

ROCE 19.8 19.9 20.3 20.7<br />

Gearing 100.0 84.9 71.5 56.9<br />

(EUR) 2012 2013e 2014e 2015e<br />

EPS 3.65 4.17 4.66 5.23<br />

% change - 14.3% 11.6% 12.4%<br />

P/E 26.6x 23.3x 20.9x 18.6x<br />

FCF yield (%) 3.3% 4.1% 4.5% 5.1%<br />

Dividends (EUR) 1.8 1.9 2.1 2.4<br />

Div yield (%) 1.9% 1.9% 2.2% 2.4%<br />

EV/Sales 3.0x 2.7x 2.5x 2.3x<br />

EV/EBITDA 18.0x 15.1x 13.7x 12.1x<br />

EV/EBIT 18.6x 16.6x 15.0x 13.4x<br />

Following a particularly enviable stockmarket performance, the share's current multiples could<br />

prompt profit-taking moves. However, we believe the share could clearly continue its uptrend in<br />

view of the quality of fundamentals, which justify higher valuation assumptions in our DCF<br />

calculation. On this basis our Fair Value works out to EUR125.<br />

ANALYSIS<br />

• In addition to the adjustments made to our forecasts following the publication of 2012<br />

earnings, we have decided to factor the effects of acquisitions into our figures for the next<br />

three years. We have assumed an annual contribution to revenue of 3%, which is at the lowend<br />

of the range indicated by the group. Note that acquisitions contributed average growth of<br />

7% a year between 2001 and 2012.<br />

• With fundamentals remaining particularly attractive, we believe the group has the ability to<br />

maintain a high level of organic growth without denting margins. As such, we have now<br />

included growth to infinity of 2.5% vs. 2% previously in our DCF assumptions. Note that<br />

between 2001 and 2012, organic growth averaged nearly 8% a year.<br />

VALUATION<br />

• The share has had an excellent ride (+50.4% 2012 +14.8% ytd) and valuation multiples are well<br />

ahead of historical average levels (2007/2013 EV/EBIT of 13.4x and P/E of 17.2x). However, we<br />

believe the share's stockmarket status could change considerably and move closer to that of<br />

Essilor and Luxottica if we compare their growth profiles. Over the next three years, our<br />

forecasts point to a 2012-15 CAGR in sales and EPS of 9.2% and 12.8%, respectively, after 2006-<br />

12 levels of 13% and 16%.<br />

NEXT CATALYSTS<br />

• Q1 revenues on 30 th April 2013;<br />

• AGM on 22 nd May 2013;<br />

• HI results on 28 August 2013.<br />

Click here to download document<br />

Analyst :<br />

Bruno de La Rochebrochard<br />

33(0) 1 56 68 75 88<br />

bdelarochebrochard@bryangarnier.com<br />

25 March 2013 5


BG’s <strong>Wake</strong> <strong>Up</strong> <strong>Call</strong><br />

Back to front page<br />

Sector View<br />

Pharmaceuticals<br />

CHMP: MS treatments in the heart of recommendations<br />

1 M 3 M 6 M 31/12/12<br />

Healthcare 3.9% 9.5% 10.2% 10.2%<br />

DJ Stoxx 600 1.9% 4.7% 6.6% 5.1%<br />

*Stoxx Sector Indices<br />

<strong>Co</strong>mpanies covered<br />

ASTRAZENECA BUY 3400p<br />

Last Price 3236p Market Cap. GBP40,390m<br />

BAYER BUY EUR75<br />

Last Price EUR78.34 Market Cap. EUR64,783m<br />

GLAXOSMITHKLINE NEUTRAL 1580p<br />

Last Price 1524p Market Cap. GBP74,807m<br />

IPSEN BUY EUR29<br />

Last Price EUR27.755 Market Cap. EUR2,338m<br />

MERCK KGaA NEUTRAL EUR100<br />

Last Price EUR115 Market Cap. EUR25,002m<br />

NOVARTIS BUY CHF70<br />

Last Price CHF66.45 Market Cap. CHF179,826<br />

NOVO NORDISK NEUTRAL DKK920<br />

Last Price DKK927.5 Market Cap. DKK419,706<br />

ROCHE HOLDING NEUTRAL CHF208<br />

Last Price CHF217.5 Market Cap. CHF152,807<br />

SANOFI BUY EUR80<br />

Last Price EUR77.5 Market Cap. EUR102,792<br />

SHIRE PLC BUY 2250p<br />

Last Price 1978p Market Cap. GBP11,020m<br />

UCB<br />

Under<br />

U.R.<br />

Last Price EUR49.38<br />

review<br />

Market Cap. EUR9,057m<br />

Last Friday, two multiple sclerosis drugs were recommended by the CHMP for approval: Aubagio<br />

from Sanofi and Tecfidera (BG-12) from Biogen. The landscape of MS drugs completely moves<br />

from subcutaneous treatments (IFN) to oral treatments. These two drugs come on the European<br />

market in direct competition with interferons such as Rebif from Merck but also with Gilenya the<br />

first oral compound in this pathology.<br />

ANALYSIS<br />

• Today the paradigm of MS treatments has two aims: to improve the efficacy, measured in<br />

terms of decrease in relapses and time to disability; and specifically to bring some additional<br />

convenience for the patient with less infusion to no infusion at all with the oral route gaining<br />

ground. Since last Friday, two new treatments have received green light to enter the market,<br />

namely Aubagio from Sanofi and Tecfidera (formerly BG12) from Biogen.<br />

• As a reminder, Aubagio was launched in the US at the end of 2012 where the first indicators<br />

were “very encouraging” with 80% of MS specialists having prescribed the drug to patients with<br />

the majority of them switching from <strong>Co</strong>paxone or Avonex whereas 20% were treatment-naïve.<br />

However Aubagio has not received the designation for a new active substance which could<br />

make Sanofi unable to apply the price expected on its drug and limit the patent protection<br />

previously expected. So far we have EUR538m peak sales for Aubagio in 2020. Sanofi thinks<br />

that the concept of a more fragmented MS market offers a greater number of therapeutic<br />

options. As a reminder Sanofi is currently building a strong MS franchise with two consecutive<br />

launches lined up for Aubagio and then Lemtrada. The group should be able to position the two<br />

products at either end of the value chain, i.e. with Aubagio being used to treat mild to<br />

moderate forms of the disease, as a substitute for interferons, and Lemtrada used to treat<br />

more severe or advanced forms. Besides during the AAN congress, Sanofi underlined that more<br />

than 80% of patients did not receive further treatment with Lemtrada in the first year of the<br />

extension of CARE MS study. Even if Lemtrada is infused intravenously, the drug presents the<br />

advantage of being only administered on 5 consecutive days and the second course given on 3<br />

consecutive days 12 months later. We expect the approval of Lemtrada in Q2 in Europe and for<br />

the end of this year in the US.<br />

• Thanks to its efficacy and the knowledge of the MS market from Biogen-Idec, Tecfidera,<br />

recommended as a first-line oral treatment for adults, could become a serious competitor in<br />

this landscape. The PDUFA date of BG12 in the US is expected on March 28th after a first threemonth<br />

delay.<br />

• In parallel, we can underline that the CHMP also recommended the extension of indication for<br />

Xarelto from Bayer for the prevention of atherothrombotic events after an Acute <strong>Co</strong>ronary<br />

Syndrome.<br />

NEXT CATALYSTS<br />

• (new) CHMP decision on April 22-25 th<br />

• PDUFA date of BG 12 on 28 th March<br />

• Approval of Lemtrada in Europe in Q2 2013 and in the US in H2.<br />

Click here to download<br />

Analyst :<br />

Martial Descoutures<br />

33(0) 1 56 68 75 18<br />

mdescoutures@bryangarnier.com<br />

Sector Team :<br />

Mathieu Chabert<br />

Eric Le Berrigaud<br />

25 March 2013 6


BG’s <strong>Wake</strong> <strong>Up</strong> <strong>Call</strong><br />

Back to front page<br />

Sector View<br />

Luxury Goods Tiffany’s Q4 earnings ahead of estimates and more optimism for 2013<br />

1 M 3 M 6 M 31/12/12<br />

Pers & H/H Gds 3.1% 6.5% 12.2% 6.8%<br />

DJ Stoxx 600 1.9% 4.7% 6.6% 5.1%<br />

*Stoxx Sector Indices<br />

<strong>Co</strong>mpanies covered<br />

CHRISTIAN DIOR BUY EUR145<br />

Last Price EUR127,75 Market Cap. EUR23,216m<br />

HERMES Intl NEUTRAL EUR200<br />

Last Price EUR262,5498 Market Cap. EUR27,717m<br />

LVMH<br />

9<br />

BUY EUR160<br />

Last Price EUR130,85 Market Cap. EUR66,429m<br />

PPR NEUTRAL EUR166<br />

Last Price EUR171,95 Market Cap. EUR21,686m<br />

PRADA BUY HKD82<br />

Last Price EUR77,3 Market Cap. EUR197,797<br />

RICHEMONT BUY CHF82<br />

Last Price CHF73,15 Market Cap. CHF38,184m<br />

SALVATORE FERRAGAMO NEUTRAL EUR20<br />

Last Price EUR21,72 Market Cap. EUR3,658m<br />

THE SWATCH GROUP BUY CHF555<br />

Last Price CHF533 Market Cap. CHF27,974m<br />

TOD'S GROUP SELL EUR80<br />

Last Price EUR110,2 Market Cap. EUR3,373m<br />

Last Friday Tiffany posted Q4 sales globally in line with market expectations and with Xmas season<br />

(stable at same-store). Despite ongoing poor trends in the U.S., TIF delivered an upbeat guidance<br />

for 2013 (“high-single digit increase”), mainly thanks to Asia-Pacific that showed some positive<br />

signs, leading to an optimistic guidance for 2013 (“mid-teens sales increase”).<br />

ANALYSIS<br />

• Q4 12 sales (ending January 31, 2013) came in at EUR1.2bn, a touch below consensus of<br />

EUR1.25bn, up 5% at constant FX but SSSG remained stable. <strong>Co</strong>mparable-store growth<br />

showed no improvement compared to the holiday season (November & December), as its<br />

domestic market (US: 52% of sales) still weighed on its quarterly performance.<br />

• US activity (52% of sales) remained sluggish with comparable-store sales down 2% in Q4. This<br />

performance was explained by disappointing sales figures at the NYC flagship store (-3% samestore),<br />

which are hit by: (i) lingering pressure in the entry-level-priced silver segment,<br />

consequence of the trade-up strategy carried-out by Tiffany and (ii) less European tourists<br />

travelling to the U.S. because of the crisis in Europe.<br />

• Good trends in Asia-Pacific (21% of sales) despite the negative calendar effect. Indeed,<br />

compared to last year when the Chinese New Year happened on January 23, the later CNY this<br />

year (February 23) did not fuelled activity in Q4 12. Despite this negative calendar shift, Tiffany<br />

posted a 6% same-store growth and witnessed positive signs in Greater China. In our view, the<br />

jewelry segment is less exposed to the current “gift-giving market” slowdown compared to the<br />

watch segment.<br />

• Soft activity in Europe (12% of sales): stable same-store sales in Q4. Whilst the trends<br />

remained surprisingly good until Q3, the last quarter was soft, notably in the U.K. Indeed the<br />

U.K. luxury group Mulberry released a profit warning last Friday because of a disappointing<br />

trading and lower spending by tourists in London. This confirms our cautious stance on Europe<br />

ahead of the Q1 13 publications.<br />

Quarterly comparable same store growth:<br />

% Q1 12 Q2 12 Q3 12 Nov-Dec 12 Q4 12<br />

Americas 0 -5 1 -2 -2<br />

Asia-Pacific 10 -5 -4 7 6<br />

Japan 12 8 5 1 2<br />

Europe 0 2 8 Stable Stable<br />

Total worldwide 4 1 1 Stable Stable<br />

Source: Tiffany<br />

• Tiffany delivered an upbeat 2013 outlook. Although Tiffany predicted a soft Q1 13 coming off a<br />

disappointing Q4 12, the group is more optimistic for 2013 and forecasts 6-8% reported sales<br />

growth (consensus: +6%e) and a high-single digit increase at constant FX, fuelled by a mid-teens<br />

sales growth in Asia-Pacific (vs. +8% in 2012). The EPS guidance is expected to be in the range of<br />

$3.43-$3.53 (consensus: $3.46), implying a 6-9% increase.<br />

READ-ACROSS TO OUR COMPANIES<br />

• Read-across to other Luxury groups is unmeaningful. Tiffany is not a pure luxury player<br />

compared to our luxury sample coverage, as its product offer varies from the high-end to the<br />

very low-end segment. However we can highlight two interesting things from Tiffany’s<br />

publication: (i) Start of the year is soft in Europe: beyond challenging comps in Q1, some luxury<br />

groups have also noticed a soft activity since tourists are less present in Europe (negative FX<br />

evolution and price hikes) and domestic customers are badly hit by the crisis; (ii) Rebound<br />

expected in Asia-Pacific: Tiffany is more optimistic about Greater China, Burberry, Hugo Boss<br />

and Swatch have also been upbeat about China in recent weeks.<br />

NEXT CATALYSTS<br />

• Tiffany will report its Q1 13 earnings on May 28 th , 2013.<br />

Analyst :<br />

Cédric Rossi<br />

33(0) 1 70 36 57 25<br />

crossi@bryangarnier.com<br />

<strong>Co</strong>nsumer Analyst Team :<br />

Loïc Morvan<br />

Peter Farren<br />

25 March 2013 7


BG’s <strong>Wake</strong> <strong>Up</strong> <strong>Call</strong><br />

Back to front page<br />

Insurance<br />

AXA<br />

Exclusive talks for the potential sale of a majority stake in AXA Private Equity<br />

Price EUR13.97 Fair Value EUR16.5 (+18%) BUY<br />

ANALYSIS<br />

Bloomberg<br />

Reuters<br />

CS FP<br />

AXAF.PA<br />

12-month High / Low (EUR) 14.6 / 8.8<br />

Market Cap (EURm) 33,357<br />

Avg. 6m daily volume (000) 6,961<br />

1 M 3 M 6 M 31/12/12<br />

Absolute perf. 2.6% 4.5% 12.0% 4.6%<br />

Insurance 3.8% 4.5% 12.3% 5.1%<br />

DJ Stoxx 600 1.9% 4.7% 6.6% 5.1%<br />

2011 2012e 2013e 2014e<br />

P/E 9.1x 7.4x 7.1x 6.8x<br />

Div yield (%) 4.9% 5.4% 5.6% 5.9%<br />

• AXA received an irrevocable offer from an investor group for its entire stake in AXA Private<br />

Equity. The acquiring investors would be composed of AXA Private Equity’s senior<br />

management, a group of institutions and French family offices. AXA should become a minority<br />

shareholder (vs. 95.8% currently). <strong>Up</strong>on the completion of the proposed transaction, AXA<br />

Private Equity’s voting share capital would be held as follows: AXA Private Equity’s<br />

management and employees 40%, external investors 33.1%, and AXA Group 26.9%.<br />

• AXA should continue to invest in private equity through AXA Private Equity funds. The expected<br />

total commitment is EUR4.8bn between 2014 and 2018. At end-2012, AXA Group had 1.4% of<br />

its General Account assets invested in private equity through AXA Private Equity.<br />

• The transaction would value AXA Private Equity at EUR510m for 100%, i.e. EUR488m for AXA<br />

Group’s share, which should be divided into an upfront payment of EUR348m and a deferred<br />

consideration of up to EUR140m, to be paid in instalments subject to achieving certain targets<br />

and meeting certain conditions. Closing is expected in Q3 2013.<br />

• Estimated impacts on AXA Group expected at the closing date: EUR0.2bn exceptional capital<br />

gain, which will be accounted for in net income, and EUR0.2bn cash expected to be remitted to<br />

the Group, net of reinvestment.<br />

-> The transaction has been expected for a long time (discussions started in September 2011) and is<br />

no breakthrough for the company.<br />

VALUATION<br />

• Based on our current 2013 estimates, our SOTP valuation is EUR16.5.<br />

NEXT CATALYSTS<br />

• AGM on 30th April 2013. Q1 2013 sales on 7th May 2013.<br />

Olivier Pauchaut, opauchaut@bryangarnier.com<br />

Healthcare<br />

Transgene<br />

An important production deal with Sanofi<br />

Price EUR8.16 Fair Value EUR21 (+157%) CORPORATE<br />

Bloomberg<br />

TNG.FP<br />

Reuters<br />

TRNG PA<br />

12-month High / Low (EUR) 11.2 / 6.8<br />

Market Cap (EURm) 260<br />

Avg. 6m daily volume (000) 34.60<br />

1 M 3 M 6 M 31/12/12<br />

Absolute perf. -6.2% 1.6% -5.7% 1.0%<br />

Healthcare 3.9% 9.5% 10.2% 10.2%<br />

DJ Stoxx 600 1.9% 4.7% 6.6% 5.1%<br />

2010 2011e 2012e 2013e<br />

P/E NS NS 6.2x 25.9x<br />

Div yield (%) NM NM NM NM<br />

ANALYSIS<br />

• Transgene and Sanofi jointly announced this morning an agreement for the production of<br />

immunotherapy products on a newly-created state of the art platform. The industrial site is<br />

located on Genzyme’s polyclonals site in Lyon.<br />

• Sanofi will therefore act as Transgene’s <strong>Co</strong>ntract Manufacturing Organisation (CMO) to<br />

manufacture clinical and commercial batches of products such as MVA therapeutic vaccines.<br />

Transgene will be a preferred customer of the platform for 15 years. As a reminder, Transgene<br />

expects to file a BLA (Biological Licence Application) for its first product TG 4010 in 2016.<br />

• An equally shared investment of EUR10m will be made by Transgene and Sanofi. We see this<br />

agreement as pivotal for Transgene’s future manufacturing capabilities. While the first strategic<br />

option would have been to build a manufacturing plant, it could have been an expensive cost<br />

for Transgene (we estimate EUR40-50m). Also, today’s agreement is non exclusive and<br />

therefore in case of the exercise of the option by Novartis for TG 4010, the Swiss pharma could<br />

also decide to produce the drug in house.<br />

VALUATION<br />

• This agreement does not imply any change in our fair value. Nevertheless, we see it as positive<br />

for Transgene mid to long term perspectives.<br />

NEXT CATALYSTS<br />

• EASL in April : strategic update on TG4040<br />

• Pexa-Vec (JX594) : first interim data for Traverse mid 2013<br />

• TG 4010 : Q4 phase IIb results<br />

Click here to download<br />

Mathieu Chabert, mchabert@bryangarnier.com<br />

25 March 2013 8


BG’s <strong>Wake</strong> <strong>Up</strong> <strong>Call</strong><br />

Back to front page<br />

25 March 2013 9


25 March 2013<br />

BG’s <strong>Wake</strong> <strong>Up</strong> <strong>Call</strong><br />

<strong>Bryan</strong> <strong>Garnier</strong> stock rating system<br />

For the purposes of this Report, the <strong>Bryan</strong> <strong>Garnier</strong> stock rating system is defined as follows:<br />

Stock rating<br />

Positive opinion for a stock where we expect a favourable performance in absolute terms over a period of 6 months from the publication of a<br />

BUY<br />

recommendation. This opinion is based not only on the FV (the potential upside based on valuation), but also takes into account a number of<br />

elements including a SWOT analysis, positive momentum, technical aspects and the sector backdrop. Every subsequent published update on the stock<br />

will feature an introduction outlining the key reasons behind the opinion.<br />

Opinion recommending not to trade in a stock short-term, neither as a BUYER or a SELLER, due to a specific set of factors. This view is intended to<br />

NEUTRAL<br />

be temporary. It may reflect different situations, but in particular those where a fair value shows no significant potential or where an upcoming binary<br />

event constitutes a high-risk that is difficult to quantify. Every subsequent published update on the stock will feature an introduction outlining the key<br />

reasons behind the opinion.<br />

Negative opinion for a stock where we expect an unfavourable performance in absolute terms over a period of 6 months from the publication of a<br />

SELL<br />

recommendation. This opinion is based not only on the FV (the potential downside based on valuation), but also takes into account a number of<br />

elements including a SWOT analysis, positive momentum, technical aspects and the sector backdrop. Every subsequent published update on the stock<br />

will feature an introduction outlining the key reasons behind the opinion.<br />

Distribution of stock ratings<br />

BUY ratings 51.4% NEUTRAL ratings 27.5% SELL ratings 21.1%<br />

<strong>Bryan</strong> <strong>Garnier</strong> Research Team<br />

HealthcareTeam Eric Le Berrigaud 33 (0) 1 56 68 75 33 eleberrigaud@bryangarnier.com<br />

Mathieu Chabert 33 (0) 1 70 36 57 45 mchabert@bryangarnier.com<br />

Martial Descoutures 33 (0) 1 56 68 75 18 mdescoutures@bryangarnier.com<br />

<strong>Co</strong>nsumer Goods Peter Farren 33 (0) 1 56 68 75 72 pfarren@bryangarnier.com<br />

Loïc Morvan 33 (0) 1 70 36 57 24 lmorvan@bryangarnier.com<br />

Cedric Rossi 33 (0) 1 70 36 57 25 crossi@bryangarnier.com<br />

IT Services Gregory Ramirez 33 (0) 1 56 68 75 91 gramirez@bryangarnier.com<br />

Insurance Olivier Pauchaut 33 (0) 1 56 68 75 49 opauchaut@bryangarnier.com<br />

Hotels/Business Services Bruno de la Rochebrochard 33 (0) 1 56 68 75 88 bdelarochebrochard@bryangarnier.com<br />

Utilities/Renewables Julien Desmaretz 33 (0) 1 56 68 75 92 jdesmaretz@bryangarnier.com<br />

<strong>Co</strong>nstruction & <strong>Co</strong>ncessions Sven Edelfelt 33 (0) 1 70 36 57 17 sedelfelt@bryangarnier.com<br />

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security discussed in this Report should call or write to our US affiliated broker, <strong>Bryan</strong> <strong>Garnier</strong> Securities, LLC. 750 Lexington Avenue, New York NY 10022. Telephone: 1-212-337-7000.<br />

This Report is based on information obtained from sources that <strong>Bryan</strong> <strong>Garnier</strong> & <strong>Co</strong>. Ltd. believes to be reliable and, to the best of its knowledge, contains no misleading, untrue or false<br />

statements but which it has not independently verified. Neither <strong>Bryan</strong> <strong>Garnier</strong> & <strong>Co</strong>. Ltd. and/or <strong>Bryan</strong> <strong>Garnier</strong> Securities LLC make no guarantee, representation or warranty as to its<br />

accuracy or completeness. Expressions of opinion herein are subject to change without notice. This Report is not an offer to buy or sell any security.<br />

<strong>Bryan</strong> <strong>Garnier</strong> Securities, LLC and/or its affiliate, <strong>Bryan</strong> <strong>Garnier</strong> & <strong>Co</strong>. Ltd. may own more than 1% of the securities of the company(ies) which is (are) the subject matter of this Report,<br />

may act as a market maker in the securities of the company(ies) discussed herein, may manage or co-manage a public offering of securities for the subject company(ies), may sell such<br />

securities to or buy them from customers on a principal basis and may also perform or seek to perform investment banking services for the company(ies).<br />

<strong>Bryan</strong> <strong>Garnier</strong> Securities, LLC and/or <strong>Bryan</strong> <strong>Garnier</strong> & <strong>Co</strong>. Ltd. are unaware of any actual, material conflict of interest of the research analyst who prepared this Report and are also not<br />

aware that the research analyst knew or had reason to know of any actual, material conflict of interest at the time this Report is distributed or made available..

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