Antigen sampling and presentation - EPFL

More documents

Recommendations

Info

Antigen sampling ntigen mpling sites ntigen mpling cells Since foreign antigens and microorganisms can enter the body at multiple sites, antigen-sampling cells are strategically located at all the possible sites of antigen entry: ‣ skin ‣ mucosal surfaces ‣ the lymph nodes for antigens that escape sampling in skin or mucosal surfaces and find their way from the tissue spaces to the lymph. ‣ in the spleen for antigens that gain access to the blood, for instance following bites by insects the resident parenchymal antigen-sampling cells. ‣ These cells take up antigen and deliver it intact to underlying APCs. ‣ Example: the epithelial M cells concentrated MALT. the migratory hematopoietic antigen-sampling cells. ‣ These cells take up antigen and transport it to distant lymphoid organs. ‣ APCs have competence for antigen processing and presentation
Antigen sampling in skin The skin harbors two populations of antigen-sampling cells: ‣ Langerhans cells, which reside within the epidermis ‣ Dermal dendritic cells, which reside within the dermis.
Page 1 and 2: Antigen sampling and presentation n
Page 3: What is an epitope cell epitope An
Page 7 and 8: Antigen sampling in skin ermal DCs
Page 9 and 10: Antigen sampling cells: Dendritic c
Page 11 and 12: Antigen Recognition by B lymphocyte
Page 13 and 14: Antigen Recognition by T lymphocyte
Page 15 and 16: Antigen Presentation: The molecules
Page 21 and 22: Professional APCs for CD4 T cells h
Page 23 and 24: How do cells present antigen? Cell
Page 25 and 26: The MHC II presentation pathway ndo
Page 27 and 28: Summary MHC are antigen-presenting

Antigen sampling and presentation - EPFL

Create successful ePaper yourself

Delete template?

Save as template?