Connective Tissue Table - Faculty.rmc.edu
Connective Tissue Table - Faculty.rmc.edu
Connective Tissue Table - Faculty.rmc.edu
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COMPOSITION, LOCATIONS, AND FUNCTIONS OF DIFFERENT TYPES OF CONNECTIVE TISSUE<br />
Type Cellular Components Extracellular Components Location/Locations Function/Functions<br />
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FIBROELASTIC TYPES (i.e., types containing both collagenous and elastic fibers)<br />
Loose Fibroblasts Collagen fibers (type I) Most organs Diffusion of materials<br />
FECT*/ Macrophages Elastic fibers (surrounds smallest vessels) (between vessels and other cells/tissues)<br />
Areolar White Adipocytes Reticular fibers Tubular organs Serves as stroma (is flexible and distortable)<br />
CT Mast Cells GAGs - e.g., (forms lamina propria)<br />
Neutrophils hyaluronic acid Surrounds glandular epithelium<br />
Eosinophils<br />
Lymphocytes<br />
Plasma cells<br />
Perivascular cells<br />
Moderately Fibroblasts Collagen fibers (type I) Most tubular organs Serves as stroma<br />
Dense Macrophages Elastic fibers (forms submucosa)<br />
FECT Reticular fibers<br />
GAGs<br />
Dense Fibroblasts Collagen fibers (type I) Dermis of skin Provides mechanical strength<br />
Irregular Macrophages Elastic fibers Outer CT "covering"<br />
FECT GAGs - e.g., (of many organs)<br />
dermatan sulfate<br />
Dense Fibroblasts Collagen fibers (type I) Cardiac "skeleton" Provides mechanical support for heart<br />
Regular Elastic fibers of heart<br />
FECT GAGs - e.g.,<br />
dermatan sulfate<br />
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*FECT = fibroelastic connective tissue
Type Cellular Components Extracellular Components Location/Locations Function/Functions<br />
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"SPECIALIZED" FIBROUS TYPES* (i.e., types with predominant fiber type)<br />
Dense Fibroblasts Collagen fibers (type I) Tendons Attachment - muscle to bone (tendon)<br />
Regular Tendinocytes GAGs - e.g., Some ligaments Attachment - bone to bone (ligament)<br />
Collagenous chondroitin sulfate Transmit forces from muscle to bone<br />
CT dermatan sulfate (thus facilitating body movements)<br />
Dense Fibroblasts Elastic fibers Intervertebral ligaments Attachment - bone to bone<br />
Regular Collagen fibers (type I) (yellow elastic ligaments)<br />
Elastic GAGs - e.g., True vocal cords<br />
CT dermatan sulfate Middle ear<br />
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*Specialized due to predominance of single fiber type and highly regular fiber orientation
Type Cellular Components Extracellular Components Location/Locations Function/Functions<br />
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"SPECIALlZED" SKELETAL TYPES (i.e., types with abundant amorphous ECM)<br />
Hyaline Cartilage Chondroblasts Collagen fibers (type II) Nasal septum Provides flexible support<br />
(hyaline type of Chondrocytes GAGs - e.g., Larynx<br />
chondrogenic CT) chondroitin sulfate Trachea<br />
keratan sulfate Bronchi<br />
hyaluronic acid Articulating surfaces of most "bones"<br />
Proteoglycans<br />
Elastic Cartilage Chondroblasts Elastic fibers Pinna/external ear Provides very flexible support<br />
(elastic type of Chondrocytes Collagen fibers (type II) Eustachian tube<br />
chondrogenic CT) GAGs - e.g., Epiglottis<br />
chondroitin sulfate Larynx<br />
keratan sulfate<br />
hyaluronic acid<br />
Fibrocartilage Chondrocytes Collagen fibers (types I, II) Intervertebral discs Provides resistance to<br />
(fibrous type of GAGs - e.g., Pubic symphysis compression and<br />
chondrogenic CT) chondroitin sulfate Knee joint shearing forces<br />
keratan sulfate Shoulder joint<br />
hyaluronic acid Mandibular joint<br />
Bone-tendon junctions<br />
Compact Bone Osteoblasts Collagen fibers (type I) Diaphysis/shaft of long "bones" Provides structural support<br />
(compact type of Osteocytes GAGs - e.g., Outer covering of all "bones" for body (especially in<br />
osseous CT) Osteoclasts chondroitin sulfate extremities)<br />
keratan sulfate<br />
Proteoglycans<br />
Glycoproteins<br />
Calcium phosphate<br />
Calcium carbonate<br />
Cancellous/Spongy Bone Osteoblasts Collagen fibers (type I) Inside skull bones, facial bones, Provides support for body<br />
(spongy type of Osteocytes GAGs - e.g., vertebrae. ribs<br />
osseous CT) Osteoclasts chondroitin sulfate Inside epiphyses of long "bones"<br />
keratan sulfate<br />
Proteoglycans<br />
Glycoproteins<br />
Calcium phosphate<br />
Calcium carbonate<br />
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Type Cellular Components Extracellular Components Location/Locations Function/Functions<br />
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"SPECIALIZED" CELLULAR TYPES* (i.e., types with more extensive cellular compartment)<br />
White White Adipocytes Reticular fibers Subcutaneous Provides padding<br />
Adipose Fibroblasts GAGs Around internal organs Fat storage<br />
CT<br />
Brown Brown Adipocytes Reticular fibers Subcutaneous Heat production<br />
Adipose White Adipocytes GAGs Around internal organs Fat storage<br />
CT Fibroblasts<br />
Reticular Reticular cells Reticular fibers Lymph nodes Provides supporting framework<br />
CT Lymphocytes GAGs Spleen for lymphoid organs<br />
Plasma cells Bone marrow<br />
Macrophages<br />
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*Specialized due to increase in cellular compartment and decrease in the extracellular compartment<br />
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EMBRYONIC TYPES (i.e., types found only in embryos/prenatal vertebrates)<br />
Mesenchyme/ Mesenchyme cells GAGs - e.g., Embryo Differentiates into all types of connective tissue<br />
Mesenchymal hyaluronic acid<br />
CT<br />
Mucous Differentiating Collagen fibers Embryo Differentiates into loose connective tissue<br />
CT Fibroblasts GAGs - e.g., Umbilical cord Serves as stroma<br />
hyaluronic acid<br />
chondroitin sulfate<br />
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