Whole report - Anglo-European College of Chiropractic
Whole report - Anglo-European College of Chiropractic
Whole report - Anglo-European College of Chiropractic
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Texas Visit<br />
In 2001, Dr. Jeff Bagust took a month’s study leave to<br />
visit the laboratories <strong>of</strong> Pr<strong>of</strong>essor W G Willis in<br />
Galveston, Texas. Pr<strong>of</strong> Willis is one <strong>of</strong> the world’s<br />
top experimental spinal physiologists, and his<br />
laboratory specialises in pain physiology, with<br />
particular emphasis on inflammatory pain. A major<br />
area <strong>of</strong> current interest is the role that nervous activity<br />
travelling backwards along sensory nerves from the<br />
spinal cord to the periphery – the Dorsal Root Reflex –<br />
may have in the generation <strong>of</strong> peripheral<br />
inflammation.<br />
Pr<strong>of</strong>essor W G Willis (left) and Dr. Jeff Bagust (right) in the<br />
research laboratory, Galveston, Texas.<br />
Jeff had worked on the dorsal root reflex for many years<br />
before joining the AECC, and was invited by Pr<strong>of</strong> Willis<br />
to visit Galveston to investigate the pharmacology <strong>of</strong><br />
the dorsal root reflex using an isolated spinal cord<br />
preparation that he has developed. Whilst there, Jeff<br />
gave a seminar on “The Isolated Spinal Cord and the<br />
Dorsal Root Reflex”.<br />
The visit was very successful. It was shown that the<br />
sensory nerves leaving the spinal cord exhibit two<br />
different patterns <strong>of</strong> antidromic (backwards)<br />
discharges, which can be distinguished using a<br />
convulsant agent, muscimol. In the absence <strong>of</strong><br />
muscimol, the dorsal root reflex consists <strong>of</strong> bursts <strong>of</strong><br />
large amplitude action potentials, but this activity is<br />
abolished by low concentrations <strong>of</strong> muscimol (2µM)<br />
and replaced by activity in nerve fibres producing very<br />
small action potentials, typical <strong>of</strong> those carrying pain<br />
signals. It seems probable that it is this small amplitude<br />
activity that is responsible for the spread <strong>of</strong><br />
inflammatory reaction and pain to sites distant from<br />
an area <strong>of</strong> damaged tissue.<br />
This work has been published in Neuroscience Letters,<br />
2002; 330: 139-142.<br />
○ ○ ○ ○<br />
Feature Reports<br />
Research Projects<br />
J Bagust PhD<br />
Reader<br />
4<br />
Cutaneous Sensitivity<br />
Palpation is one <strong>of</strong> the major investigative techniques<br />
used by chiropractors, and a considerable amount<br />
<strong>of</strong> time is spent by students at the AECC learning<br />
palpatory techniques. Palpatory skills are essentially<br />
subjective and difficult to quantitate, but a series <strong>of</strong><br />
three BSc projects (PS Chandhok, IE Foster, MC de<br />
Jager) have attempted to measure aspects <strong>of</strong> sensory<br />
acuity that might contribute to palpatory ability and<br />
be expected to change with training.<br />
Two parameters have been measured; 2 point<br />
discrimination threshold (2-PD)- a measure <strong>of</strong> the<br />
minimum distance between a pair <strong>of</strong> points touched<br />
on the tip <strong>of</strong> the index finger that can be identified as<br />
two, and not one; and the thickness <strong>of</strong> paper through<br />
which a thin nylon mon<strong>of</strong>ilament can be accurately<br />
located (the Palpation Threshold).<br />
Comparison <strong>of</strong> 1 st year students who had no training<br />
in palpation, with 5 th year students who were using<br />
palpation techniques in the clinic on a daily basis,<br />
showed that the experienced group were able to<br />
identify two points touched on the skin more easily<br />
than the inexperienced students, and they were also<br />
able to locate the filament under a greater thickness<br />
<strong>of</strong> paper.<br />
This indicates that the fingers <strong>of</strong> the 5 th year students<br />
were more sensitive than those <strong>of</strong> the 1 st year students,<br />
giving support to the suggestion that it is possible to<br />
improve palpatory ability by appropriate training.<br />
1.82<br />
1.27<br />
2-Point Discrimination (2-PD) and Palpation Thresholds (PT) obtained from<br />
1 st and 5 th year chiropractic students. (Mean ± SEM)<br />
3.36<br />
3.92