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Annual Report 2008 - 2009 - Liverpool School of Tropical Medicine

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CLINICAL<br />

GROUP<br />

FINDING SOLUTIONS FOR THE<br />

PROBLEM OF POVERTY IN TB CONTROL<br />

The Collaboration for Research on Equity and<br />

Systems for TB and HIV/AIDS (CRESTHA) at LSTM,<br />

has this year continued to support pragmatic<br />

trials <strong>of</strong> health system interventions aimed at<br />

improving access by the poor to TB services. The<br />

Triage-Plus work with informal providers (featured<br />

in the 2006/07 <strong>Annual</strong> <strong>Report</strong>) has continued in<br />

Sudan and Malawi with valuable support from the<br />

Norwegian Heart & Lung Patient Organisation. A<br />

new trial is also now underway in Hunan Province<br />

in China. This is testing the effect on TB case<br />

notifications <strong>of</strong> removing up-front, out-<strong>of</strong>-pocket<br />

payments for health services from patients with<br />

chronic cough symptoms. Instead <strong>of</strong> patients<br />

having to pay up-front and then be reimbursed<br />

later by China’s New Co-operative Medical<br />

Scheme (NCMS), the NCMS is directly covering<br />

costs incurred by TB dispensaries in two counties<br />

(Lingxiang and Miluo). A third, similar county<br />

(Huarong) is acting as a control.<br />

LSTM operates the Secretariat <strong>of</strong> the TB & Poverty<br />

Subgroup and this facilitates our ability to reach<br />

a global audience for the policy and practice<br />

implications <strong>of</strong> our work.<br />

This year the Secretariat has been championing<br />

a call for consultations and tests for patients with<br />

chronic cough symptoms to be free <strong>of</strong> charge<br />

at the point <strong>of</strong> access. The Secretariat hosted a<br />

debate within the Global Stop-TB Partnership<br />

Forum in Rio De Janeiro entitled ‘A TB-Free World<br />

requires Free TB diagnosis’ and the resulting<br />

recommendation was included in the Rio<br />

Declaration on TB control. Another achievement<br />

this year has been the contribution <strong>of</strong> a chapter<br />

on Access and Impact Assessment in the Scientific<br />

Blueprint for Development <strong>of</strong> New Diagnostics.<br />

CRESTHA was amongst a team <strong>of</strong> partners led by<br />

The International Union Against Tuberculosis and<br />

Lung Disease in a successful bid to the United<br />

States Agency for International Development<br />

(USAID) for a multi-million dollar, five-year<br />

collaborative research grant named TREAT-TB<br />

(Technology, Research, Education And Technical<br />

Assistance for Tuberculosis). CRESTHA will be<br />

responsible for the impact evaluation <strong>of</strong> this<br />

work – principally on the extent to which the<br />

new interventions serve the needs <strong>of</strong> the poor<br />

and facilitate progress towards the Millennium<br />

Development Goals. The first years <strong>of</strong> research are<br />

focusing on field evaluations <strong>of</strong> new diagnostic<br />

tests for TB.<br />

PROFESSOR DAVID LALLOO MB BS MD FRCP FFTM RCPS (Glasg)<br />

HEAD OF CLINICAL RESEARCH GROUP<br />

CLINICAL DIRECTOR AND PROFESSOR IN CLINICAL TROPICAL MEDICINE<br />

DIRECTOR OF WELLCOME TRUST LIVERPOOL TROPICAL CENTRE<br />

David’s main research interests are in clinical trials and epidemiological studies in resource poor<br />

settings, particularly in HIV related infections, malaria and envenoming. He has collaborations<br />

and studies in a number <strong>of</strong> countries including Uganda, Malawi, Sri Lanka and Vietnam. He<br />

holds an appointment as Honorary Consultant at the Royal <strong>Liverpool</strong> University Hospital.<br />

12 LSTM ANNUAL REPORT

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