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Methamphetamine - UCLA Integrated Substance Abuse Programs

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Promising Pharmacotherapies?‣ Newton, T. et al (Biological Psychiatry, Dec, 2005)Bupropion reduces craving and reinforcing effects ofmethamphetamine in a laboratory self-administrationstudy.‣ Elkashef, A. et al (Neuropsychopharmcology(Neuropsychopharmcology, , 2007)Bupropion reduces meth use in an outpatient trial,with particularly strong effect with less severe users.‣ Tiihonen, , J. et al (recently completed; reported at theACNP methamphetamine satelite meeting in Kona,Hawaii) Methylphenidate SR (sustained release) hasshown promise in a recent Finnish study with veryheavy amphetamine injectors.

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