PSRC 58th Annual Meeting - Plastic Surgery Research Council

PSRC 58 th Annual MeetingMay 2- 4, 2013Loews Santa Monica Beach Hotel, Santa Monica, CaliforniaHosted by University of California Los AngelesThursday, May 2, 20136:30 am - 5:00 pm Registration7:00 - 8:00 am Continental Breakfast8:00 - 10:30 am Local Program Session 1Moderator: Jim Bradley10:30 - 11:00 am Coffee with Exhibitors11:00 am - 12:00 pm Local Program Session 2Moderator: Jim Bradley12:00 - 12:15 pm Members’ Photograph12:30 - 2:00 pm Lunch - Non-Members12:30 - 2:00 pm Lunch & Business Meeting - Members only2:00 - 3:00 pm Panel 1: Past Chairs’ Panel: Innovations in Our SubspecialtiesModerator: TBDCo-Moderator: TBDPanelists: TBD3:00 – 3:30 pm Coffee with Exhibitors3:30 – 5:00 pm Session 1 Best PapersModerator: TBDCo-Moderator: TBD3:30 pm 1TRACHEAL ALLOTRANSPLANTATION AND PREFABRICATION FOR LONGTRACHEAL STENOSIS WITH WITHDRAWAL OF IMMUNOSUPPRESSION. FROMBED TO BENCHPresenter: Margot Den Hondt, MDAffiliation: UZ LeuvenCo-Authors: Vranckx JJ; Delaere P3:40 pm 2

RESIDENT INVOLVEMENT AFFECTS PLASTIC SURGERY OUTCOMES: ANANALYSIS OF 10,356 PATIENTS FROM THE NSQIP DATABASEPresenter: Sumanas W Jordan, MDAffiliation: Northwestern University Feinberg School of MedicineCo-Authors: Mioton LM, Smetona J, Aggarwal A, Wang E, Dumanian GA, Kim JY3:50 pm 3ATP HYDROLYSIS REDUCES NEUTROPHIL INFILTRATION AND NECROSIS INPARTIAL-THICKNESS SCALD BURNS IN MICEPresenter: Sara De La Rosa, BSAffiliation: Univerity of MichiganCo-Authors: Bayliss J; Peterson JR; Eboda ON; Lisiecki JL; Rinkinen JR; Xi C; Su GL;Cederna PS; Wang SC; Levi B4:00 pm 4MULTIPLE REGENERATIVE PERIPHERAL NERVE INTERFACES (RPNIS)PRODUCE INDEPENDENT FUNCTIONS WHEN NEUROTIZED WITH TRANSECTEDAND SPLIT NERVEPresenter: Edward P Washabaugh IV, StudentAffiliation: University of MichiganCo-Authors: Langhals NB; Kung TA; Moon JD; Cederna PS; Urbanchek MG4:10 pm 5NEURAL CREST TRANSCRIPTOME SCREEN IDENTIFIES NOVEL GENETICREGULATORS IN CRANIOFACIAL DEVELOPMENTPresenter: Yawei Kong, PhDAffiliation: Massachusetts General Hospital Harvard Medical SchoolCo-Authors: Grimaldi M; Liao EC4:20 pm 6HIGH-FIDELITY TISSUE ENGINEERING OF PATIENT-SPECIFIC AURICLES FORRECONSTRUCTION OF PEDIATRIC MICROTIA: LONG-TERM RESULTSPresenter: Alyssa J Reiffel, MDAffiliation: Weill Cornell Medical CollegeCo-Authors: Brown BN; Hernandez KA; Perez JL; Campbell R; Boyko T; Zhou S;Bonassar LJ; Spector JA4:30 pm 7IMAGING WITH INDOCYANINE GREEN-LOADED MONOCYTES FORDIFFERENTIATION OF CUTANEOUS INFLAMMATORY STATES IN A MOUSEMODELPresenter: Joani M Christensen, MDAffiliation: Johns Hopkins School of MedicineCo-Authors: Chen Y; Brat GA; Buretta KJ; Cooney DS; Brandacher G; Johnson KE;Lee WP; Li X; Sacks JM4:40 pm 8SILENCE THE RAGE: TARGETED INHIBITION OF THE RECEPTOR FORADVANCED GLYCATED ENDPRODUCTS (RAGE) RESTORES REGENERATIVEFUNCTION IN DIABETESPresenter: Stelios C Wilson, BAAffiliation: Predoctoral Research FellowCo-Authors: Lalezarzadeh F; Soares MA; Lotfi P; Ham MJ; OJO CO; Sartor RA;Saadeh PB; Ceradini DJ

4:50 pm 9CONDITIONAL NEURAL CREST CELL ABLATION TO INTERROGATECRANIOFACIAL REGENERATION IN VERTEBRATE MODELPresenter: Michael Grimaldi, StudentAffiliation: Massachusetts General Hospital Harvard Medical SchoolCo-Authors: Grimaldi M; Liao EC5:00 – 6:00 pm Session 2 Best PapersModerator: TBDCo-Moderator: TBD5:00 pm 10ARE POSTOPERATIVE ANTIBIOTICS FOR IMMEDIATE BREASTRECONSTRUCTION NECESSARY? RESULTS OF A PROSPECTIVE RANDOMIZEDCLINICAL TRIALPresenter: Brett T Phillips, MDAffiliation: Stony Brook University Medical CenterCo-Authors: Fourman MS; Dagum AB; Huston TL; Ganz JC; Khan SU; Bui DT5:10 pm 11EVALUATING BONY OSTEOSYNTHESIS AND PAIN AFTER RIGID STERNALFIXATION VERSUS TRADITIONAL WIRE CLOSURE IN HIGH-RISK STERNOTOMYPATIENTS RESULTS OF A PROSPECTIVE, RANDOMIZED, MULTICENTER,INTERNATIONAL TRIALPresenter: Michael S Wong, MDAffiliation: University of California DavisCo-Authors: Lehmann S; Zehr K; DeGuzman BJ; Aklog L; Garrett HE; MacMahon H;Hatcher BM; Raman J5:20 pm 12DIET-INDUCED OBESITY IMPAIRS LYMPHATIC TRANSPORT AND FUNCTIONPresenter: Evan S Weitman, MDAffiliation: Memorial Sloan Kettering Cancer CenterCo-Authors: Zampell JC; Elhadad S; Aschen S; Farias-Eisner G; Cuzzone DA; GhantaS; Albano N; Mehrara BJ5:30 pm 13PDE-5 INHIBITION IMPROVES SKIN FLAP VIABILITY IN RATS THAT AREEXPOSED TO NICOTINEPresenter: Ajul Shah, MDAffiliation: Yale UniversityCo-Authors: Pfaff M; Wu W; Steinbacher D5:40 pm 14THE OSTEOINDUCTIVE EFFECTS OF A NOVEL OXYSTEROL ON RABBIT BONEMARROW STROMAL CELLSPresenter: Reza Jarrahy, MDAffiliation: UCLA REBAR LabCo-Authors: Li A; Hokugo A; Sorice S; Buck A; Zuk P5:50 pm 15SEVERE INFECTIOUS COMPLICATIONS FOLLOWING FRONTAL SINUSFRACTURE: THE IMPACT OF OPERATIVE DELAY AND PERI-OPERATIVEANTIBIOTIC USEPresenter: Justin L Bellamy, BS

7:00 – 10:00 pm Welcome ReceptionAffiliation: Johns Hopkins SOMCo-Authors: Molendijk J; Reddy SK; Flores JM; Mundinger GS; Manson PN; RodriguezED; Dorafshar AHFriday, May 3, 20137:00 – 8:30 am Continental Breakfast with Exhibitors8:30 – 10:00 am Session 3 Best PapersModerator: TBDCo-Moderator: TBD8:30 am 16COMPARISON OF FREE FIBULAR FLAPS TO REAMER-IRRIGATOR-ASPIRATOR(RIA) SYSTEM FOR RECONSTRUCTION OF CRITICAL SIZED PORCINEMANDIBULAR DEFECTSPresenter: Raja Mohan, MDAffiliation: Johns Hopkins University and University of MarylandCo-Authors: Brown EN; Mundinger GS; Kelamis JA; Bojovic B; Chrsity MR; DorafsharAH; Rodriguez ED8:40 am 17THE MEDIAL GASTROCNEMIUS FLAP: IS IT A VIABLE OPTION FOR FREEMUSCLE TRANSFER TO RESTORE ELBOW FLEXION?Presenter: Steven H Bailey, MDAffiliation: UT Southwestern Medical CenterCo-Authors: Ramanadham S; Cheng J8:50 am 18NOTCH3 KNOCKDOWN IN HEMANGIOMA STEM CELLS ALTERS HEMANGIOMAFORMATION IN A MURINE MODELPresenter: Alvin WongAffiliation: Columbia UniversityCo-Authors: Thirumoorthi A; Andrews J; Hardy K; England R; Shawber CJ; KitajewskiJ; Wu JK9:00 am 19P21 AS A REGULATOR OF LYMPHANGIOGENESIS IN WOUND HEALING ANDINFLAMMATIONPresenter: Gina T Farias-Eisner,Affiliation: Memorial Sloan Kettering Cancer CenterCo-Authors: Aschen SZ; Weitman ES; Cuzzone DA; Albano NJ; Ghanta S; Mehrara BJ9:10 am 20A NOVEL TRANSGENIC LINE WITH IRF6 DRIVING EXPRESSION OF REPORTERPresenter: Lisa Gferer, MDAffiliation: Massachusetts General HospitalCo-Authors: Kamel G; Liao EC9:20 am 21FUNCTIONAL ANALYSIS OF WNT SIGNALING MODULATORS WNT9A, FRZBAND FZD7A IN CRANIOFACIAL CONVERGENCE AND EXTENSIONMORPHOGENESIS

Presenter: Tatiana Hoyos, MDAffiliation: MGHCo-Authors: Kamel G; Dougherty M; Tse W; Shubinets V; Grimaldi M; Liao E9:30 am 22FIBROMODULIN REPROGRAMMED CELLS FOR BONE AND SKELETAL MUSCLEREGENERATIONPresenter: Zhong Zheng, PhDAffiliation: University of California Los Angeles Los AngelesCo-Authors: Jian J; Zhang X; Velasco O; Chung G; Hourfar A; Zhang K; Lee K; Ting K;Soo C9:40 am 23THERAPEUTIC TARGETING OF PUMA OVEREXPRESSION MITIGATES CHRONICRADIATION INJURYPresenter: Philip Lofti, MDAffiliation: NYU School of MedicineCo-Authors: Low YC; Soares M; Ham MJ; Wilson SC; Lalezarzadeh F; Ojo CO; SartorRA; Levine JP; Saadeh PB; Ceradini DJ9:50 am 24EX-VIVO ASSEMBLY AND TRANSPLANTATION OF A STEM CELL-DERIVEDHYBRID GRAFT USING THE LGR6+ EPITHELIAL STEM CELL ON COMMONACELLULAR MATRICES FOR TREATMENT OF FULL THICKNESS SOFT TISSUEWOUNDSPresenter: Denver M Lough, MD, PhDAffiliation: Johns HopkinsCo-Authors: Cooney DS; Mendenhall SD; Yang M; Reichensperger JD; Cox LA;Cosenza NM; Wetter N; Harrison CE; Neumeister MW10:00 – 10:30 am Coffee with Exhibitors10:30 – 11:30 am Session 4 Group A: MiscellaneousModerator: TBDCo-Moderator: TBD10:30 am 25CRANIAL DISTRACTION OSTEOGENESIS ON SYNDROMICCRANIOSYNOSTOSIS: LONG-TERM FOLLOW-UP AND EFFECT ONPOSTOPERATIVE CRANIAL GROWTHPresenter: Kazuaki Yamaguchi, MDAffiliation: Osaka City General HospitalCo-Authors: Imai KI; Fujimoto TF; Takahashi MT; Maruyama YM10:40 am 26ASSESSMENT OF SIGNALING PATHWAYS TO ACTIVATE ADIPOSE-DERIVEDSTEM/STROMAL CELLS (ASCS) AFTER ADIPOSE TISSUE INJURY: POSSIBLETHERAPEUTIC TOOLS FOR ADIPOGENSIS AND ANGIOGENESISPresenter: Shinichiro Kuno, Graduate StudentAffiliation: Tokyo UniversityCo-Authors: Doi K; Mineda K; Kinoshita K; Kato H; Yoshimura K10:50 am 27PREVENTION OF CAPSULAR CONTRACTURE WITH PHOTOCHEMICAL TISSUEPASSIVATIONPresenter: Justin R Fernandes, MD

Affiliation: Massachusetts General HospitalCo-Authors: Salinas HM; Broelsch GF; McCormack MC; Meppelink AM; Randolph MA;Redmond RW; Austen WG, Jr11:00 am 28NOVEL POINT OF CARE IMAGING METHODOLOGY TO DETECT HETEROTOPICOSSIFICATIONPresenter: Benjamin Levi, MDAffiliation: University of Michigan/Stanford UniversityCo-Authors: Peterson J; De La Rosa S; Okabare P; Cilwa K; Oluwatobi E; Morris M;Kozloff K; Cederna PS; Buchman SR; Wang SC11:10 am 29LONG-TERM FOLLOW UP OF INTERPOSITIONAL NERVE GRAFTING OF THEPROSTATIC PLEXUS AFTER OPEN PROSTATECTOMYPresenter: Paul S Cederna,Affiliation: University of MichiganCo-Authors: Waljee JF; Curtin CM; Wei JT; Montie JE; Kung TA11:20 am 30BACTERICIDAL SURGICAL DRAIN DEVELOPMENTPresenter: Andrew D Navarrete, MDAffiliation: University of WisconsinCo-Authors: Tighe DR; Hoegh KN; Platner LC; Powers TA; Marshall TS; Tyler ME;Poore SO10:30 – 11:30 am Session 4 Group B: MiscellaneousModerator: TBDCo-Moderator: TBD10:30 am 31INCREASED CAMP INHIBITS BASAL AND PDGF-INDUCED CELL MIGRATION INDUPUYTREN S CONTRACTURE-DERIVED FIBROBLASTSPresenter: Latha Satish, PhDAffiliation: University of PittsburghCo-Authors: Liu F; Kathju S10:40 am 32SENTINEL LYMPH NODE BIOPSY FOR MELANOMA IS THERE A CORRELATIONBETWEEN PREOPERATIVE LYMPHATIC MAPPING WITH SURGICAL LYMPHNODES HARVESTED?Presenter: Kristen A Hudak, MDAffiliation: Medical College of WisconsinCo-Authors: Hudak KE; Dzwierzynski WW10:50 am 33RADIOGRAPHIC EVALUATION OF LIGAMENT INJURIES ASSOCIATED WITHDISTAL RADIUS FRACTURESPresenter: Ronit WollsteinAffiliation: University of PittsburghCo-Authors: Shakir S; Gilula L; Naran S11:00 am 34PHYSIOLOGIC CHANGES WITH ABDOMINAL WALL RECONSTRUCTION IN APORCINE MODEL OF ABDOMINAL COMPARTMENT SYNDROMEPresenter: Howard D Wang,Affiliation: Johns Hopkins University and University of Maryland

Co-Authors: Tong A; Lee JC; Federico C; Bradley JP3:00 pm 49TISSUE EXPANDER BREAST RECONSTRUCTIONS EXPERIENCE FEWERCOMPLICATIONS WHEN SKIN FLAPS ARE ASSESSED WITH LASERFLUORESCENT ANGIOGRAPHY RATHER THAN CLINICAL JUDGEMENT ALONEPresenter: Patrick Garvey, MDAffiliation: UT MD Anderson Cancer Ctr.Co-Authors: Selber JC; Hobaugh CW; Zhang H; Butler CE; Baumann DP3:10 pm 50COMPARISON OF CLINICAL OUTCOMES AND PATIENT SATISFACTION INIMMEDIATE SINGLE-STAGE VERSUS TWO-STAGE IMPLANT-BASED BREASTRECONSTRUCTIONPresenter: Ingrid Ganske, MDAffiliation: Brigham and Women's HospitalCo-Authors: Susarla S; Helliwell L; Morris D; Eriksson E; Chun Y3:20 pm 51MAJOR SURGICAL AND RESPIRATORY COMPLICATIONS FOLLOWINGCOMPLEX ABDOMINAL WALL RECONSTRUCTION AN ANALYSIS OF 1,102HERNIA REPAIRS WITH COMPONENT SEPARATION FROM NSQIP DATASETPresenter: Jonas A Nelson, ResidentAffiliation: University of PennsylvaniaCo-Authors: Nelson JN; Kovach SK3:30 pm 52PEDIATRIC MANDIBLE FRACTURES: DEMOGRAPHICS, TREATMENT,OUTCOMES, AND AN ASSESSMENT OF GROWTH AND DEVELOPMENTPresenter: Darren M Smith, MDAffiliation: University of PittsburghCo-Authors: Naran S; Cray J; Bykowski M; Shakir S; Rottgers S; Losee JE3:40 pm 53EFFECTS ON ABDOMINAL WALL DYNAMICS AFTER VENTRAL HERNIA REPAIRBY COMPONENT SEPARATIONPresenter: Jeffrey H Kozlow, MDAffiliation: University of Michigan Medical SchoolCo-Authors: Lisiecki JL; Zhang PC; Rinkinen JR; Terjimanian MN; Brownley RC;Holcombe SA; Wang SC; Kuzon WM; Levi B3:50 pm 54DO POSTOPERATIVE COMPLICATIONS PREDICT REGRET TO UNDERGOMICROSURGICAL BREAST RECONSTRUCTION?Presenter: Toni Zhong, MD, MHSAffiliation: university health networkCo-Authors: Bagher S; Zeng D, Metacalf K, Hofer S2:30 – 4:00 pm Session 6 Group B: Craniofacial/BoneModerator: TBDCo-Moderator: TBD2:30 pm 55DENTAL PULP STEM CELL CLEFT GENES DIFFERENTIAL EXPRESSION ANDDEVELOPMENTAL INFLUENCE DURING PALATOGENESISPresenter: Ginger C Slack, BS

Affiliation: UCLACo-Authors: Yuan J; Bueno B; Bradley JP2:40 pm 56FURTHER DEFINING THE ROLE OF RANK/RANKL/OPG AXIS IN CRANIALSUTURE BIOLOGY.Presenter: Maureen Beederman, Medical StudentAffiliation: University of ChicagoCo-Authors: Lee JC; Rajan M; Kim S; He TC; Reid RR2:50 pm 57PUTATIVE GENES DOWNSTREAM OF FGFR2 CONTRIBUTING TO CORONALSUTURE SYNOSTOSIS IN A C342Y CROUZON MURINE MODELPresenter: Samintharaj Kumar, MBBS BDS MRCS MFDSRCS MFDRCSIAffiliation: University College London Institute of Child HealthCo-Authors: Peskett E; Britto JA; Pauws E3:00 pm 58COMBINED ACTION OF AMIFOSTINE WITH DEFEROXAMINE RESTORESMETRICS OF CALLUS MINERALIZATION IN A MODEL OF PATHOLOGICFRACTURE HEALING AFTER RADIOTHERAPYPresenter: Christian Figueredo, Medical StudentAffiliation: University of MichiganCo-Authors: Henry M; Figuredo C; Ahsan S; Deshpande SS; Felice PA; Nelson NS;Buchman SR3:10 pm 59DEVELOPMENT OF AN ELASTIC BIODEGRADABLE NANOCOMPOSITE DEVICEFOR TISSUE DISTRACTIONPresenter: Nicole Levi-Polyachenko, PhDAffiliation: Wake Forest Baptist HealthCo-Authors: Rosenbalm T; Wagner W; David L; Sanger C; Morykwas M; Argenta L;Wood B3:20 pm 60CALVARIAL BONE HEALING IN THE ABSENCE OF TLR2 AND TLR4Presenter: Melissa A Shaw, BSAffiliation: University of PittsburghCo-Authors: Wang D; Gilbert JR; Kubala AA; Shakir S; Losee JE; Billiar TR; CooperGM3:30 pm 61A NOVEL COMBINATION OF AMIFOSTINE PROPHYLAXIS AND ANGIOGENICDEFEROXAMINE PROTECTS AND RESTORES BIOMECHANICAL PROPERTIESOF BONE IN PATHOLOGIC FRACTURE HEALING AFTER RADIOTHERAPYPresenter: Salman Ahsan, StudentAffiliation: University of MichiganCo-Authors: Donneys A; Deshpande SS; Felice PA; Figuredo C; Henry M; Page E;Buchman SR33:40 pm 62BIOPATTERNED TGFB1 HEALS CALVARIAL DEFECTS IN A JUVENILE RABBITCORONAL STRIP SUTURECTOMY MODELPresenter: Sameer Shakir, BSAffiliation: University of PittsburghCo-Authors: MacIsaac ZM; Naran S; Gilbert JR; Cray JJ; Wang D; Kubala AA; LoseeJE; Cooper GM

3:50 pm 63PARATHYROID HORMONE REVERSES RADIATION INDUCEDHYPOVASCULARITY IN A MURINE MODEL OF DISTRACTION OSTEOGENESISPresenter: Stephen Y Kang, MDAffiliation: University of MichiganCo-Authors: Deshpande SS; Donneys A; Nelson NS; Rodriguez J; Felice PA; ChepehaDB; Buchman SR2:30 – 4:00 pm Session 6 Group C: NerveModerator: TBDCo-Moderator: TBD2:30 pm 64VON FREY MEASUREMENTS DISCRIMINATE BETWEEN SITE SENSATIONPresenter: Andrej Nedic, BSEAffiliation: University of MichiganCo-Authors: Moon JD; Kung TA; Langhals NB; Cederna PS; Urbanchek MG2:40 pm 65A NOVEL IMAGING TECHNIQUE FOR EVALUATING AXONAL REGENERATIONAFTER PERIPHERAL NERVE TRANSECTION IN A RODENT MODELPresenter: Joanna H Ng, MDAffiliation: Massachusetts General HospitalCo-Authors: Jung Y; Keating CP; Senthil-Kumar P; Meppelink AM; Randolph MA;Evans CL; Winograd JM2:50 pm 66C7 NERVE ROOT SENSORY MAPPING: A FUNCTIONAL MRI INVESTIGATIONPresenter: Jacques A Machol IV, MDAffiliation: Medical College of WisconsinCo-Authors: Li R; Hettinger PC; Flugstad NA; Yan JG; Matloub HS; Hyde JS3:00 pm 67RESTORATION OF PERIPHERAL NERVE AFTER ACUTE INJURY USINGEPINEURAL SHEATH CONDUIT ENHANCED WITH BONE MARROW STROMALCELLS IN DIABETIC CONDITIONSPresenter: Gregorz J. Kwiecien, MDAffiliation: Cleveland ClinicCo-Authors: Lukaszuk M; Uygur S; Madajka M; Cwykiel J; Siemionow M3:10 pm 68IMPLANTED ELECTRODE WITH CONDUCTIVE POLYMER AUGMENTS SIGNALTRANSDUCTION FROM THE REGENERATIVE PERIPHERAL NERVE INTERFACEPresenter: Theodore A Kung, ResidentAffiliation: University of MichiganCo-Authors: Langhals NB; Moon JD; Qu J; Martin DC; Cederna PS; Urbanchek MG3:20 pm 69NEUREGULIN-1 / ERBB2 SIGNALING REGULATES EARLY AXONALREGENERATION FOLLOWING PERIPHERAL NERVE INJURYPresenter: James M Hendry, MDAffiliation: University of TorontoCo-Authors: Placheta E; Gordon T; Borschel GH

3:30 pm 70ENHANCEMENT OF CROSS-FACE NERVE GRAFTS WITH END-TO-SIDESENSORY NERVE PROTECTIONPresenter: Maria C Alvarez Veronesi, MCAffiliation: University of TorontoCo-Authors: Placheta E; Lafontaine CA; Liu E; Wood MD; Gordon T; Frey M; BorschelGH3:40 pm 71OPTICAL CONTROL OF PERIPHERAL NERVE SIGNAL TRANSMISSIONPresenter: Sahil K Kapur, MDAffiliation: UNIVERSITY OF WISCONSIN MADISONCo-Authors: Richner T; Williams JC; Poore SO3:50 pm 72SIGNAL TRANSDUCTION FROM SKELETAL MUSCLE VIA THIN-FILM POLYIMIDEELECTRODE ARRAYSPresenter: Nicholas B Langhals, PhDAffiliation: University of MichiganCo-Authors: Larson JV; Urbanchek MG; Cederna PS; Kung TA4:00 – 4:30 pm Coffee with Exhibitors and Poster Presentations4:30 – 6:00 pm Session 7 Group A: Developmental BiologyModerator: TBDCo-Moderator: TBD4:30 pm 73PROPRANOLOL ACTION IS MEDIATED VIA THE BETA-2 ADRENERGICRECEPTOR IN HEMANGIOMA STEM CELLSPresenter: Ryan W England, StudentAffiliation: Columbia UniversityCo-Authors: Banerjee D; Shawber CJ; Kitajewski A; Kitajewski J; Wu JK4:40 pm 74NON-CANONICAL TGFβ SIGNALING REGULATES TONGUE DEVELOPMENTPresenter: Akiko Suzuki, DDS, PhDAffiliation: University of Southern CaliforniaCo-Authors: Iwata J; Sanchez-Lara PA; Urata M; Chai Y4:50 pm 75ROLE OF EPITHELIUM-MESENCHYME INTERACTIONS DURING SOFT PALATEDEVELOPMENTPresenter: Junichi Iwata, DDS, PhDAffiliation: University of Southern CaliforniaCo-Authors: Suzuki A; Sanchez-Lara PA; Urata M; Chai Y5:00 pm 76A NOVEL FETAL ECM PROVIDES A NICHE FOR STEM CELL RECRUITMENT ANDTISSUE REGENERATIONPresenter: Robert C Rennert, MDAffiliation: Stanford UniversityCo-Authors: Sorkin M; Garg RK; Januszyk M; Gurtner GC5:10 pm 77APPLICATION OF ZEBRAFISH NEURAL CREST CULTURE ASSAYS TOELUCIDATE STEM CELL PROPERTIES

Presenter: Beste Kinikoglu, PhDAffiliation: Massachusetts General Hospital and Harvard Medical SchoolCo-Authors: Kong Y; Liao EC5:20 pm 78IL-6 AS A SERUM MARKER FOR LYMPHEDEMAPresenter: Daniel Cuzzone, MDAffiliation: Memorial Sloan Kettering Cancer CenterCo-Authors: Zampell JC; Weitman E; Aschen S; Farias-Eisner G; Ghanta S; Albano N;Mehrara BJ5:30 pm 79EXAMINING THE ROLE OF MACROPHAGES IN PROLIFERATING INFANTILEHEMANGIOMASPresenter: Alvin WongAffiliation: Columbia UniversityCo-Authors: Hardy K; England R; Shawber CJ; Kitajewski J; Wu JK5:40 pm 80PROPRANOLOL EFFECTS ON MESENCHYMAL STEM CELLS ARE NOTMEDIATED VIA INHIBITION OF MAPKPresenter: Alex Kitajewski, StudentAffiliation: Columbia UniversityCo-Authors: Kitajewski A; Banerjee D; Shawber CJ; Kitajewski J; Wu JK5:50 pm 81COMPONENTS SEPARATION FOR ABDOMINAL WALL RECONSTRUCTION: THEPITTSBURGH EXPERIENCE, A REVIEW OF 311 CONSECUTIVE SINGLESURGEON CASES.Presenter: Sanjay Naran, MDAffiliation: University of PittsburghCo-Authors: Emilife P; Quigley M; Shakir S; Cray Jr J; Russavage J; Nguyen V4:30 – 6:00 pm Session 7 Group B: Craniofacial/BoneModerator: TBDCo-Moderator: TBD4:30 pm 82EXOGENOUS ADMINISTRATION OF RHBMP-7 DURING DISTRACTIONOSTEOGENESIS ON TRABECULAR BONE FORMATION; A DOSE-RESPONSESTUDYPresenter: Ali Izadpanah, MDAffiliation: McGill UniversityCo-Authors: Alsalmi L; Hamdy R; Lessard L4:40 pm 83THE USE OF SMART SCAFFOLDS IN HEALING CRANIOFACIAL DEFECTS:PRELIMINARY IN VITRO STUDIESPresenter: Akishige Hokugo, DDS, PhDAffiliation: UCLA REBAR LabCo-Authors: Li A; Buck A; Nguyen P; Li J; Jarrahy R4:50 pm 84COMPARING THE EFFICACY OF DEFEROXAMINE OR AMIFOSTINE PRE-TREATMENT IN THE PREVENTION OF OSTEORADIONECROSIS OF THE MURINEMANDIBLEPresenter: Brendan J Alleyne, BS

Affiliation: Case Western Reserve University School of MedicineCo-Authors: Varghai D; Askeroglu U; Gliniak C; Tobin K; Zwiebel S; Gosain AK5:00 pm 85AMIFOSTINE OFFERS PROTECTION OF OSTEOCYTE VIABILITY DURINGFRACTURE HEALING AFTER RADIOTHERAPYPresenter: Joshua P Spiegel, StudentAffiliation: University of MichiganCo-Authors: Donneys A; Sarhaddi D; Tchanque-Fossuo CN; Ahsan S; Deshpande SS;Buchman SR5:10 pm 86DEFEROXAMINE INDUCES THE RESTORATION OF MINERALIZATION METRICSOF IRRADIATED BONE IN DISTRACTION OSTEOGENESISPresenter: Erin E Page, BSAffiliation: University of Michigan School of MedicineCo-Authors: Felice PA; Donneys A; Ahsan S; Deshpande SS; Perosky JE; Kozloff KM;Buchman SR5:20 pm 87FACIAL INFILTRATING LIPOMATOSIS IS CAUSED BY PIK3CA ACTIVATINGMUTATIONSPresenter: Reid Maclellan, MDAffiliation: Boston Childrens Hospital Harvard Medical SchoolCo-Authors: Greene AK; Luks VL; Mulliken JB; Warman ML; Kurek KC5:30 pm 88STEM CELL THERAPY REMEDIATES MANDIBULAR VASCULOGENESISFOLLOWING RADIATION AND DISTRACTION OSTEOGENESISPresenter: Sagar S Deshpande, BSAffiliation: University of Michigan Medical SchoolCo-Authors: Donneys A; Gallagher KK; Tchanque-Fossuo CN; Felice PA; Sun HL;Krebsbach PH; Buchman SR5:40 pm 89OUTCOMES IN CRANIOPLASTY - RISK FACTORS AND CHOICE OFRECONSTRUCTIVE MATERIALPresenter: Sashank K Reddy, MD, PhDAffiliation: Johns Hopkins UniversityCo-Authors: Khalifian S; Flores J; Bellamy J; Borsuk D; Manson PN; Rodriguez E;Dorafshar AH5:50 pm 90INFLUENCED CALVARIAL HEALING AFTER BONE COMPONENTSIMPLANTATION IN THE ABSENCE OF TLR2 AND TLR4Presenter: Dan Wang, DMDAffiliation: University of PittsburghCo-Authors: Gilbert JR; Shakir S; Shaw MA; Kubala AA; Losee JE; Billiar TR; CooperGM4:30 – 6:00 pm Session 7 Group C: Tissue EngineeringModerator: TBDCo-Moderator: TBD

4:30 pm 91A PROMISING CONCEPT OF ORGAN TISSUE ENGINEERING USINGAUTOLOGOUS DECELLULARIZED MICROCIRCULATORY BEDS ASVASCULARIZED BIOSCAFFOLDSPresenter: Lars H Evers, MDAffiliation: Stanford UniversityCo-Authors: Liu W; Simons D; Sorkin M; Longaker MT; Gurtner GC4:40 pm 92DETERMINING THE IN VITRO AND IN VIVO IMMUNE RESPONSE TOWARDSDECELLULARIZED AND RECELLULARIZED PORCINE TRACHEAL ALLOGRAFTSFOR AIRWAY TRANSPLANTATIONPresenter: Siba Haykal, BSc, MD, Phd Candidate, ResidentAffiliation: University of TorontoCo-Authors: Zhou Y; Marcus P; Salna M; Machuca T; Hofer SO; Waddell TK4:50 pm 93INJECTABLE GEL GRAFT FOR CRANIAL BONE DEFECT REPAIRPresenter: Bo Han, PhDAffiliation: University of Southern CaliforniaCo-Authors: Yang Z; Fang J; Nimni M; Tayag C; Urata M5:00 pm 94STROMAL CELL DERIVED FACTOR (SDF)-1 WITH BMP-2 AND TGF-B1 INDUCESSITE DIRECTED CELL HOMING, OSTEOGENIC AND CHONDROGENICDIFFERENTIATION WITHOUT THE REQUIREMENT FOR CELL SEEDINGPresenter: Harvey Chim, MDAffiliation: Case Western Reserve UniversityCo-Authors: Miller E; Gliniak C; Alsberg E5:10 pm 95THE EFFECT OF ADIPOSE-DERIVED STEM CELLS AND PLATELET-RICHPLASMA FOR THE REPAIR OF THE CALVARIAL BONE DEFECT IN A MURINEMODELPresenter: Hiroshi Mizuno, MDAffiliation: Juntendo UniversityCo-Authors: Tajima S; Tobita M; Orbay H; Hyakusoku H5:20 pm 96CONTROLLED REPAIR OF A RABBIT CRANIAL DEFECT BY SUSTAINEDDELIVERY OF LOW-DOSE BONE MORPHOGENETIC PROTEIN-2 (BMP2)ENCAPSULATED IN PLGA MICROSPHERESPresenter: Jason D Wink, BAAffiliation: Perelman School of Medicine at the University of PennsylvaniaCo-Authors: Gerety PA; Sherif R; McGrath JL; Clarke NA; Nah HD; Taylor JA5:30 pm 97ENGINEERING NEO-TRACHEA WITH DE-EPITHELIZED CRYOPRESERVEDTRACHEAL ALLOGRAFT SCAFFOLDPresenter: Ning Zeng, MDAffiliation: the University of Texas MD Anderson Cancer Center

Co-Authors: Zeng N; Wang L; Zang M; Johnson J; Yu P; Zhang Q5:40 pm 98MICROSTRUCTURED COLLAGEN SCAFFOLDS FACILITATE DETERMINISTICGUIDANCE OF CELLS DURING WOUND REPAIRPresenter: Daniel Garcia,Affiliation: Weill Cornell Medical CollegeCo-Authors: Reiffel AJ; Hernandez KA; Delnero P; Garcia D; Boyko T; Spector JA5:50 pm 99PHOTOCHEMICAL CROSSLINKING STABILIZES PROTEIN HYDROGELS FORCARTILAGE REGENERATIONPresenter: Xing Zhao, MDAffiliation: Massachusetts General Hospital and Harvard Medical SchoolCo-Authors: Omobono MA; Jang S; Randolph MA; Redmond RW; Gill TJ; YaremchukMJ7:00 – 9:00 pm Members DinnerSaturday, May 4, 20137:00 – 8:30 am Continental Breakfast with Exhibitors8:30 – 10:30 am Session 8 Group A: OutcomesModerator: TBDCo-Moderator: TBD8:30 am 100BREAST RECONSTRUCTION OUTCOMES FOLLOWING NIPPLE-SPARINGMASTECTOMYPresenter: Amy S Colwell, MDAffiliation: Harvard Medical School/ MA General HospitalCo-Authors: Tessler O; Lin AM; Liao E; Winograd J; Cetrulo CL; Tang R; Smith BL;Austen WG8:40 am 101NIPPLE-AREOLAR COMPLEX NECROSIS AFTER NIPPLE SPARINGMASTECTOMY WITH IMMEDIATE IMPLANT-BASED RECONSTRUCTION: RISKFACTORS AND THE SUCCESS OF CONSERVATIVE TREATMENTPresenter: Kevin Small,Affiliation: New York Presbyterian Hospital Weill CornellCo-Authors: Dent B; Talmor M8:50 am 102TRADITIONAL ABDOMINOPLASTY VS. PROGRESSIVE TENSION SUTURE (PTS)ABDOMINOPLASTY : A SINGLE CENTER, SINGLE SURGEON 6 YEARRETROSPECTIVE REVIEW OF COMPLICATION RATESPresenter: Cristina Dracea, MDAffiliation: Long Island Plastic Surgical GroupCo-Authors: Alizadeh K

9:00 am 103REVIEW OF OUTCOMES AFTER USE OF THE IMPLANTABLE COOK DOPPLERPROBE VERSUS THE SYNOVIS FLOW COUPLER FOR POST-OPERATIVEMONITORING OF FREE FLAP BREAST RECONSTRUCTIONPresenter: Grace Um,Affiliation: University of Washington Medical CenterCo-Authors: Said HK; Colohan S; Neligan PC; Mathes DW9:10 am 104PREDICTORS OF POST-MASTECTOMY RECONSTRUCTION IN ANUNDERSERVED POPULATIONPresenter: Erik M Wolfswinkel, ScBAffiliation: Baylor College of MedicineCo-Authors: Lopez SN; Weathers WM; Qashqai SM; Wang T; Hilsenbeck SG; RimawiMF; Heller L9:20 am 105IMPROVING OUTCOMES AND REDUCING MORBIDITY IN CONGENITALMYELOMENINGOCELE DEFECTS: A COHORT COMPARISON STUDY BETWEENMUSCLE FLAPS VERSUS ADIPOFASCIAL FLAPS WITH SUPPLEMENTALDERMAL REGENERATIVE TEMPLATESPresenter: Oluwaseun A Adetayo, MDAffiliation: University of PittsburghCo-Authors: Argenta A; MacIsaac Z; Grunwaldt LJ; Kumar AR9:30 am 106SUBMUCOUS CLEFT PALATE SPEECH OUTCOMES WORSE THAN CLEFTPALATE ONLY OUTCOMES DESPITE ELIMINATING SYNDROMES A NOVELCOMPARISON GROUP UTILIZING AGE AND ANATOMY MATCHINGPresenter: Alexander Y Lin, MDAffiliation: Saint Louis University School of MedicineCo-Authors: Gildea TH; Shirnov R; Laurent L9:30 am 107INCREASED FLAP WEIGHT AND DECREASED PERFORATOR NUMBERPREDICTS FAT NECROSIS IN DIEP BREAST RECONSTRUCTIONPresenter: Carolyn L Mulvey, BSAffiliation: Johns Hopkins University School of MedicineCo-Authors: Cooney CM; Daily FF; Colantuoni E; Ogbuago OU; Cooney DS; Rad AN;Manahan MA; Rosson GD; Sacks JM9:50 am 108DOES SPECIALTY TRAINING MATTER?: A MULTIVARIATE REGRESSIONANALYSIS OF PANNICULECTOMIES PERFORMED BY PLASTIC AND NON-PLASTIC SURGEONSPresenter: Lauren M Mioton, BSAffiliation: Northwestern University Feinberg School of MedicineCo-Authors: Buck II DW; Gart MS; Hanwright PJ; Wang E; Kim JY10:00 am 109HEALTH RELATED QUALITY OF LIFE AFTER BREAST RECONSTRUCTIVESURGERY: AN INTERIM ANALYSISPresenter: Rika Ohkuma, MDAffiliation: Johns Hopkins Medical InstitutionCo-Authors: Lacayo Baez M; Rad AN; Manahan MA; Sacks JM; Cooney DS; CooneyCM; Rosson GD

10:10 am 110COMPARISON OF PERCUTANEOUS RELEASE, OPEN RELEASE, ENDOSCOPICAND CORTICOSTEROID INJECTION IN THE TREATMENT OF TRIGGER DIGITS; ASYSTEMATIC REVIEW AND META-ANALYSISPresenter: Arash Izadpanah, MDAffiliation: McGill UniversityCo-Authors: Zein M; Izadpanah A; Kanevsky J; Izadpanah A; Belzile E; Shafran V;Shararah A; Luc M; Zadeh T10:20 am 111A SYSTEMATIC REVIEW OF INFECTION IN BREAST RECONSTRUCTION:AUTOLOGOUS FLAP VERSUS IMPLANT RECONSTRUCTIONPresenter: Svetlana Danovich, MDAffiliation: Stony Brook University Medical CenterCo-Authors: Phillips B; Verma R; Bishawi M; Dagum AB; Bui DT; Khan SU8:30 – 10:30 am Session 8 Group B: CTAModerator: TBDCo-Moderator: TBD8:30 am 112ANTI HLA IMMUNISATION RELATED TO SKIN ALLOGRAFT IN EXTENSIVELYBURNED PATIENTS: ASSESSMENT IN POTENTIAL CANDIDATES FORVASCULARIZED COMPOSITE ALLOTRANSPLANTS.Presenter: Mikael Hivelin, MD, PhDAffiliation: Henri Mondor HospitalUniversity Paris 12Co-Authors: Duhamel PD; Suberbielle CS; Jacquelinet CJ; Audry BA; Bargues LB; BeyEB; Lantieri LL8:40 am 113THE USE OF MOBILIZED STEM CELLS MORE RELIABLY INDUCES TOLERANCETO VASCULARIZED COMPOSITE ALLOGRAFTS IN MISMATCHED DOGSCOMPARED TO BONE MARROWPresenter: Jeff ChangAffiliation: University of Washington Medical CenterCo-Authors: Swearingen B; Hwang B; Miwongtum-Butts T; Graves S; Storb R; MathesDW8:50 am 114INDOLEAMINE-2,3-DIOXYGENASE IS CRITICAL TO MESENCHYMAL STEMCELL-BASED ALLOGRAFT TOLERIZATIONPresenter: Marc A Soares, MDAffiliation: NYU Medical CenterCo-Authors: Low YC; Ham MJ; Lalezarzadeh F; Wilson SC; Ojo CO; Lotfi P; SaadehPB; Ceradini DJ9:00 am 115INFUSED BONE MARROW FAILS TO PROLONG VASCULARIZED COMPOSITEALLOGRAFT SURVIVAL IN NONHUMAN PRIMATESPresenter: Philip Brazio, BAAffiliation: University of Maryland School of MedicineCo-Authors: Bojovic B; Ha JS; Brown EN; Panda A; Munivenkatappa R; Shipley ST;Rodriguez ED; Bartlett ST; Barth RN9:10 am 116

CUTANEOUS LYMPHATIC RECONSTITUTION OCCURS DURING THE ACUTEINFLAMMATORY PHASE IN A RAT ORTHOTOPIC HIND LIMBTRANSPLANTATION MODELPresenter: Kate J Buretta, BSAffiliation: Johns Hopkins University School of MedicineCo-Authors: Brat GA; Christensen JM; Ibrahim Z; Grahammer J; Furtmueller G; SuamiH; Cooney DS; Andrew Lee WP; Brandacher G; Sacks JM9:20 am 117TOTAL FACE AND MULTI-ORGAN PROCUREMENT FROM A BRAIN-DEADDONOR: INSTITUTIONAL EXPERIENCE AND PROPOSED ALGORITHMPresenter: Philip Brazio, MDAffiliation: University of Maryland School of MedicineCo-Authors: Bojovic B; Dorafshar AH; Garcia JP; Brown EN; Bartlett ST; Barth RN;Rodriguez ED9:30 am 118CHARACTERIZATION OF HUMAN DI-CHIMERIC CELLS A NEW TOLERANCEINDUCING CELLULAR THERAPY IN TRANSPLANTATION: A PRELIMINARYSTUDYPresenter: Joanna Cwykiel, MSAffiliation: Cleveland ClinicCo-Authors: Askar M; Siemionow M9:40 am 119CHARACTERIZING THE IMMUNOMODULATORY PROPERTIES OF CADAVERICDONOR VERTEBRAL BONE MARROW USED IN HAND TRANSPLANTATIONPresenter: Gerald Brandacher, MDAffiliation: Johns Hopkins University School of MedicineCo-Authors: Sarkar K; Lemas MV; Bitzan J; Sproul JD; Lee WP; Brandacher G;Cooney DS9:50 am 120INVESTIGATING THE IMMUNOREGULATORY PROPERTIES OF ADIPOSE-DERIVED STEM CELLS IN AN IN VITRO MOUSE MODEL OF RECONSTRUCTIVETRANSPLANTATIONPresenter: Damon S Cooney, MDAffiliation: Johns Hopkins University School of MedicineCo-Authors: Wu LW; Sarkar K; Mao Q; Lee WP; Brandacher G; Cooney DS10:00 am 121IDENTIFICATION OF A TUMOR-DERIVED FACTOR CAUSING T CELLTOLEROGENIC EFFECTSPresenter: Brian Maybruck, PhDAffiliation: Clevland ClinicCo-Authors: Gastman BR10:10 am 122MISMATCHED VCA TRANSPLANTATION WITHOUT THE NEED FOR DONORCELL CHIMERISM: A MODEL TO ACHIEVE TOLERANCE WHILE ELIMINATINGCHRONIC IMMUNOSUPPRESSION AND THE RISKS OF GVHDPresenter: Bruce SwearingenAffiliation: University of Washington Medical CenterCo-Authors: Chang J; Graves S; Hwang B; Miwongtum-Butts T; Storb R; Mathes DW

10:20 am 123TOPICAL GENE SILENCING: TOWARDS AN OFF-THE-SHELF SOLUTIONPresenter: Maria J Ham, PG StudentAffiliation: New York University Medical CenterCo-Authors: Soares MA; Zhou AT; Ayaz MM; Wetterau M; Lotfi P; Lalezarzadeh F;Wilson SC; Ojo CO; Bandekar A; Sofou S; Ceradini DJ; Saadeh PB8:30 – 10:30 am Session 8 Group C: MicrosurgeryModerator: TBDCo-Moderator: TBD8:30 am 124CHOOSING THE OPTIMAL TIMING FOR CONTRALATERAL SYMMETRYPROCEDURES FOLLOWING UNILATERAL FREE FLAP BREASTRECONSTRUCTIONPresenter: Eric I Chang, MDAffiliation: Fox Chase Cancer CenterCo-Authors: Chang EI; Selber JC; Nosrati N; Zhang TH; Robb GL; Chang DW8:40 am 125TOWARDS A SAFER DESIGN OF PERFORATOR FLAPS: THE PERFUSIONANGLE THEORYPresenter: Alexis Laungani, StudentAffiliation: Mayo ClinicCo-Authors: Lachman N; Primus J; Kirchoff R; Saint-Cyr M8:50 am 126THE INTEROSSEOUS KEYSTONE PERFORATOR ISLAND FLAP (IKPIF): ANOVEL TECHNIQUE FOR MINIMIZING RADIAL FOREARM FLAP DONORMORBIDITYPresenter: Michael W Findlay, MBBS, PhD, FRACSAffiliation: Stanford UniversityCo-Authors: Rozen WM; Pratt G; Fairbank S; Choi WT; Hunter-Smith D; Behan FC;Gurtner GC9:00 am 127FABRICATION OF CELLULAR PRE-VASCULARIZED TISSUE CONSTRUCTSFROM AUTOGENOUS TISSUEPresenter: Karina A Hernandez, ResidentAffiliation: Weill Cornell Medical CollegeCo-Authors: Reiffel AJ; Campbell R; Pino A; Harper A; Derrick K; Spector JA9:10 am 128A PROSPECTIVE STUDY OF TRANSIT TIME FLOW VOLUME (TTFV)MEASUREMENT FOR INTRA-OPERATIVE EVALUATOIN AND OPTIMIZATION OFFREE FLAPSPresenter: Jesse Selber, MDAffiliation: University of Texas MD Anderson Cancer CenterCo-Authors: Garvey PB; Clemens MW; Chang EI; Zhang H; Hanasono MW9:20 am 129QUANTITATIVE FLUORIMETRY FOR DETECTING VASCULAR COMPROMISE INMICROVASCULAR SURGERY: 8300 READINGS WITH 100% NEGATIVEPREDICTIVE VALUEPresenter: Johnny T Chang, MD, MSMEAffiliation: The Buncke Clinic at California Pacific Medical CenterCo-Authors: Safa B; Parrett BM; Buncke GM; Buntic RF

9:30 am 130UTILITY OF PRE-OPERATIVE MRA IN ASSESSING GRACILIS FLAP VASCULARANATOMYPresenter: Jamie A Schwartz, MDAffiliation: St Lukes Roosevelt Hospital CenterCo-Authors: Smith M; Dayan JH; Sultan MR; Kagen A; Iyer AR; Samson W9:40 am 131USING MOTION ANALYSIS TO PROVIDE IMMEDIATE FEEDBACK INMICROSURGERY EDUCATIONPresenter: Ji Son, MSAffiliation: StanfordCo-Authors: Satterwhite T; Lee GK9:50 am 132EVALUATION OF FACIAL ARTERY ON CT ANGIOGRAPHY USING 64 SLICEMDCT: IMPLICATIONS FOR FACIAL RECONSTRUCTION IN PLASTIC SURGERYPresenter: David W Mathes, MDAffiliation: University of Washington Medical CenterCo-Authors: Mathes DW; Furukawa M; Anzai Y10:00 am 133INDOCYANINE GREEN ANGIOGRAPHY PREDICTS FLAP PEDICLE VENOUSCONGESTION WITHIN ONE MINUTE OF OCCLUSION IN RAT MODELSPresenter: Mitchell S Fourman, MPhilAffiliation: Stony Brook University Medical CenterCo-Authors: Nasser A; Mathison M; Phillips BT; Gersch R; Gelfand M; Bui DT10:10 am 134USING REAL-TIME THREE-DIMENSIONAL FOURIER-DOMAIN OPTICALCOHERENCE TOMOGRAPHY FOR INTRAVITAL IMAGING OF THROMBOSISPresenter: Qixu Mao, MDAffiliation: Johns Hopkins University School of MedicineCo-Authors: Huang Y; Zhu S; Tong D; Ibrahim Z; Christensen J; Pang J; Cooney DS; LiJ; Li Y; Lee WP; Kang JU; Brandacher G10:20 am 135BIOENGINEERED RECONSTRUCTION OF UPPER DIGESTIVE TRACT.Presenter: Andrew Polyakov, MDAffiliation: P A Herzen Moscow Cancer Research InstituteCo-Authors: Reshetov I; Polyakov A; Batukhtina E; Filushin M10:30 – 11:00 am Coffee with Exhibitors11:00 am – 12:00 pm Session 9 Group A: Ischemia/Reperfusion InjuryModerator: TBDCo-Moderator: TBD11:00 am 136DEFINING THE SALVAGE TIME WINDOW FOR THE USE OF ISCHEMIC POST-CONDITIONING IN SKELETAL MUSCLE ISCHEMIA REPERFUSION INJURYPresenter: Mei Yang, MDAffiliation: Southern Illinois University School of MedicineCo-Authors: Mendenhall SD; Taylor NC; Reichensperger J; Derby B; Neumeister MW

11:10 am 137MODULATION OF ER STRESS RESPONSES THROUGH AN IDO (INDOLEAMINE2,3 DIOXYGENASE) DEPENDENT STEM CELL THERAPY IN A MURINE HIND-LIMB ISCHEMIA-REPERFUSION INJURY MODELPresenter: Mohamad Masoumy, MDAffiliation: Georgia HealthCo-Authors: Yu JC; Liu JY; Mozaffari MS; Baban B11:20 am 138COMBINED HYPOXIC PRECONDITIONING AND POSTCONDITIONING DO NOTCONFER ADDITIVE PROTECTION OF EX VIVO HUMAN SKELETAL MUSCLEFROM ISCHEMIA/REPERFUSION INJURYPresenter: Andreas Naparus, MRCS MBBS BSc (Hons) AICSMAffiliation: The Hospital for Sick Children TorontoCo-Authors: Ashrafpour H; Huang N; Hofer SO; Zhong T; Forrest CR; Pang CY11:30 am 139EX VIVO MESENCHYMAL STEM CELL THERAPY PROTECTS VASCULARNETWORKS FROM ISCHEMIA REPERFUSION INJURYPresenter: Mark McRae, MDAffiliation: NYU Medical CenterCo-Authors: McRae MH; Ham MJ; Wilson SC; Lotfi P; Lalezarzadeh F; Ojo CO;Saadeh PB; Ceradini DJ11:40 am 140PRETREATMENT OF SILDENAFIL ATTENUATES EARLY LUNG ISCHEMIA-REPERFUSION INJURY IN A RAT MODELPresenter: JianXun Chen, MDAffiliation: China Medical University HospitalCo-Authors: Chen JX; Cheng CM11:50 am 141THE INFLUENCE OF PRE-EXISTING LOWER EXTREMITY EDEMA AND VENOUSSTASIS DISEASE ON BODY CONTOURING OUTCOMESPresenter: Evan B Katzel, MDAffiliation: The University of Pittsburgh Medical CenterCo-Authors: Nayar HS; Davenport MP; Bossert RP; Rubin JP; Gusenoff JA11:00 am – 12:00 pm Session 9 Group B: OtherModerator: TBDCo-Moderator: TBD11:00 am 142NATIONAL TRENDS IN MICROSURGICAL BREAST RECONSTRUCTIONECONOMICS: INCREASING ACADEMIC RECONSTRUCTION WITH DECREASINGREIMBURSEMENTPresenter: Manish Champaneria, MDAffiliation: Loma Linda University Medical CenterCo-Authors: Workman A; Mattison G; Gupta S11:10 am 143RECOMBINANT SPIDER SILK AS BIOMATERIAL IN MEDICAL APPLICATIONPresenter: Stefan LangerAffiliation: Leipzig University HospitalCo-Authors: Zeplin PH, Mougin N; Jordan MC; Berninger AK; van Gelder P; Leimer A;Langer S; Scheibel T

11:20 am 144FACTORS AFFECTING ACCESS TO BREAST RECONSTRUCTIONPresenter: Benjamin C Wood, MDAffiliation: Wake Forest Baptist HealthCo-Authors: DAVID LR; MCNATT MH; LEVINE EA; THOMPSON JT11:30 am 145AN ASSESSMENT OF PRE-CLINICAL MEDICAL STUDENT KNOWLEDGE: WHATCONSTITUTES THE FIELD OF PLASTIC SURGERY?Presenter: Russell E Kling, Medical StudentAffiliation: University of PittsburghCo-Authors: Nayar HS; Harhay MO; Emelife PI; Manders EK; Ahuja NK11:40 am 146DO PLASTIC SURGERY DIVISION HEADS AND PROGRAM DIRECTORS HAVETHE TOOLS NECESSARY TO PROVIDE EFFECTIVE LEADERSHIP?Presenter: Jugpal S Arneja, MD, MBAAffiliation: BC Childrens Hospital University of British ColumbiaCo-Authors: McInnes CW; Carr NJ; Lennox P; Petersen R; Skarlicki D11:50 am 1472011 DUTY HOURS REGULATIONS AND HOME CALL - PERSPECTIVES OFPLASTIC SURGERY RESIDENTSPresenter: Brian C Drolet, MDAffiliation: Brown University and Rhode Island HospitalCo-Authors: Prsic A; Schmidt ST11:00 am – 12:00 pm Session 9 Group C: Tissue EngineeringModerator: TBDCo-Moderator: TBD11:00 am 148CHARACTERIZATION OF SIGNAL ISOLATION IN BIOTIC AND ABIOTIC RPNISCAFFOLDSPresenter: John V Larson, MSAffiliation: University of MichignCo-Authors: Kung TA; Urbanchek MG; Cederna PS; Langhals NB11:10 am 149TISSUE ENGINEERED TENDON-BONE COMPOSITE GRAFTS FORRECONSTRUCTION OF THE TENDON-BONE INTERFACE - AN EXPERIMENTALSTUDY IN RATPresenter: Simon Farnebo, MD PhDAffiliation: Stanford UniversityCo-Authors: Woon CY; Bronstein JA; Schmitt T; Lindsey DP; Chang J11:20 am 150THE EFFECT OF CONTROL-RELEASED BASIC FIBROBLAST GROWTH FACTORINCORPORATED IN β-TRICALCIUM PHOSPHATE FOR CRANIALREGENERATION IN A MURINE MODELPresenter: Azusa Shimizu, MDAffiliation: Juntendo University School of MedicineCo-Authors: Tajima S; Tobita M; Tanaka R; Mizuno H; Tabata Y

11:30 am 151FAT GRAFT ENGINEERING BY DECELLULARIZED HUMAN ADIPOSE MATRIXAND ADIPOSE-DERIVED STEM CELLSPresenter: Lina Wang, PhDAffiliation: MDACCCo-Authors: Wang L; Johnson JA; Iyyanki TS; Zhang Q; Beahm EE11:40 am 152DECELLULARIZED MUSCULOFASCIAL MATRIX FOR SOFT TISSUE REPAIR ANDREGENERATIONPresenter: Joshua Johnson, MSAffiliation: the University of Texas MD Anderson Cancer CenterCo-Authors: Johnson JA; Wang LN; Chang DW; Zhang QX11:50 am 153FABRICATION OF PREVASCULARIZED TYPE I COLLAGEN TISSUEENGINEERED CONSTRUCTS FOR IN VIVO MICROANASTOMOSISPresenter: Rachel Campbell, MDAffiliation: Weill Cornell Medical CollegeCo-Authors: Reiffel AJ; Hernandez KA; Garcia D; Delnero P; Boyko T; Spector JA12:00 – 1:30 pm Lunch1:00 – 3:30 pm Session 10 Group A: OutcomesModerator: TBDCo-Moderator: TBD1:00 pm 154ESTROGEN RECEPTORS ALPHA AND BETA EXPRESSION IN BREAST IMPLANTCAPSULES: EXPERIMENTAL FINDINGS AND CLINICAL CORRELATESPresenter: Francesco Segreto, MDAffiliation: Campus BioMedico di Roma UniversityCo-Authors: Carotti S; Marangi GF; Tosi D; Morini S; Persichetti P1:10 pm 155RECONSTRUCTION AFTER MASTECTOMY FOR BREAST CANCER ISASSOCIATED WITH IMPROVED SURVIVAL: AN UPDATE ON A SINGLEINSTITUTION STUDYPresenter: Jennifer L Baker, MDAffiliation: University of California San Diego UCSDCo-Authors: Mailey BA; Tokin CA; Blair SL; Wallace AM1:20 pm 156CURRENT TREATMENT FOR INFANTILE HEMANGIOMAS: SELECTIONCRITERIA, SAFETY AND OUTCOMES USING ORAL PROPRANOLOLPresenter: Harry Nayar,Affiliation: University of PittsburghCo-Authors: MacIsaac ZM; Gehris R; Mehta D; Geiser S; Grunwaldt LJ1:30 pm 157QUALITY OF LIFE OUTCOMES ASSOCIATED WITH NIPPLE SPARINGMASTECTOMY AND BREAST RECONSTRUCTIONPresenter: Christopher R Bailey, BAAffiliation: Johns Hopkins Hospital

Co-Authors: Ohkuma R; Mohan R; Rad AN; Manahan MA; Sacks JM; Cooney DS;Tsangaris T; Rosson GD1:40 pm 158HUMAN ACELLULAR DERMIS VERSUS SUBMUSCULAR TISSUE EXPANDERBREAST RECONSTRUCTION: A MULTIVARIATE ANALYSIS OF SHORT-TERMCOMPLICATIONS BASED ON THE NATIONAL SURGICAL QUALITYIMPROVEMENT PROGRAM (NSQIP) DATABASEPresenter: Armando Davila, BSAffiliation: Northwestern University Feinberg School of MedicineCo-Authors: Seth AK; Wang E; Hanwright PJ; Bilimoria K; Fine N; Kim JY1:50 pm 159ANALYSIS OF CLINICALLY SIGNIFICANT SEROMA FORMATION IN BREASTRECONSTRUCTION USING ACELLULAR DERMAL GRAFTSPresenter: Brett Michelotti, MDAffiliation: Pennsylvania State University Milton S Hershey Medical CenterCo-Authors: Brooke S; Mesa J; Wilson M; Moyer K; Mackay D; Neves RI; Potochny J2:00 pm 160CAPSULAR CONTRACTURE: ANGIOGENESIS AND ROLE OF ESTROGENRECEPTOR IN PERIPROSTHETIC TISSUE REMODELING.Presenter: Daniele Tosi, MDAffiliation: UNIVERSITY CAMPUS BIOMEDICO OF ROMECo-Authors: SEGRETO F; CAROTTI S; MARANGI G; MORINI S; PERSICHETTI P2:10 pm 161DRESSING WEAR TIME AFTER BREAST RECONSTRUCTION: PRELIMINARYRESULTS OF A RANDOMIZED CONTROLLED TRIALPresenter: Daniela F Veiga, MD, PhDAffiliation: Federal University of Sao Paulo and Universidade do Vale do SapucaiCo-Authors: Veiga-Filho J; Mendes DA; Sales EM; Damasceno CA; Ferreira LM2:20 pm 162ANALYSIS OF THE VERTICAL MAMMAPLASTY INCISION APPROACH TO SKIN-SPARING MASTECTOMY AND IMMEDIATE AUTOLOGOUS TISSUERECONSTRUCTIONPresenter: Ahuja Naveen,Affiliation: University of Pittsburgh Medical CenterCo-Authors: Gimbel ML; Smith DA2:30 pm 163COMPREHENSIVE ANALYSIS AND STRATEGIES TO MINIMIZE DONOR SITEMORBIDITY IN ABDOMINAL FREE FLAP BREAST RECONSTRUCTIONPresenter: Edward I Chang, MDAffiliation: MD Anderson Cancer CenterCo-Authors: Chang EI; Soto-Miranda MA; Zhang T; Nasrati N; Kronowitz SJ; Butler CE;Chang DW2:40 pm 164SELECTIVE NEURECTOMY, TENSOR FASCIA LATA MYOMECTOMY ANDLIPOSUCTION FOR TOTAL LEG CONTOURING: ANATOMIC AND BIOCHEMICALRESEARCHES WITH THEIR CLINICAL IMPLICATIONSPresenter: FC Tsai, MD, PhDAffiliation: Taipei Medical University Hospital2:50 pm 165

DOES MESH LOCATION MATTER IN ABDOMINAL WALL RECONSTRUCTION? ASYSTEMATIC REVIEW OF THE LITERATURE AND A SUMMARY OFRECOMMENDATIONSPresenter: Frank Albino, MDAffiliation: UCLACo-Authors: Fan KL; Patel KM; Bhanot P; Nahabedian MY3:00 pm 166IMPACT OF CONNECTIVE TISSUE DISEASE ON OUTCOMES FOLLOWINGBREAST SURGERY AND RECONSTRUCTIONPresenter: Kenneth L Fan, MDAffiliation: UCLACo-Authors: Patel KM; Franklin B; Albino FP; Nahabedian MY3:10 pm 167SYSTEMATIC REVIEW OF PATIENT-CENTERED OUTCOMESFOLLOWINGLOWER EXTREMITY FLAP RECONSTRUCTION IN CO-MORBIDPATIENTSPresenter: James Economides, BSAffiliation: UCLACo-Authors: Marshall E; Patel KM; Fan KL; Attinger C; Evans KK3:20 pm 168FUNCTIONAL OUTCOMES IN RECONSTRUCTION OF MASSIVE CHEST WALLDEFECTS: A 17-YEAR EXPERIENCEPresenter: Mark W Clemens, MDAffiliation: MD Anderson Cancer CenterCo-Authors: Garvey PB; Corkum JP; Baumann DP; Hofstetter W; Butler CE1:00 – 3:30 pm Session 10 Group B: Fat GraftingModerator: TBDCo-Moderator: TBD1:00 pm 169AUTOLOGOUS STEM CELLS THERAPY CAN IMPROVE SOFT TISSUEEXPANSION AND ACCELERATE SKIN REGENERATION DURING EXPANSIONPresenter: Shuangbai Zhou, MDAffiliation: Shanghai Jiao Tong UniversityCo-Authors: Li QF; Zan T; Gu B; Liu K; Xie Y; Gan YK; Chiang CA; Wang J; Xu KM; PuLQ1:10 pm 170REGULATION OF WNT SIGNALING IN ADIPOSE DERIVED STEM CELLSIMPROVES ADIPOGENIC POTENTIALPresenter: Sudheer K Ravuri, PhDAffiliation: University of PittsburghCo-Authors: Philips BJ; Kling RE; Interval JD; Kashkoush AI; Meyer EM; Pfeifer ME;Zimmerlin L; Donnenberg VS; Donnenberg AD; Marra KG; Rubin JP1:20 pm 171IN VITRO COMPARISON OF THE IMMUNOREGULATORY EFFECTS OF BONEMARROW AND ADIPOSE DERIVED STEM CELLS.Presenter: Lehao Wu, MDAffiliation: Johns Hopkins Medical InstitutionCo-Authors: Yuan N; Rubin JP; Christensen J; Grahammar J; Ibrahim Z; Lee A;Schneeberger S; Sacks JM; Cooney DS; Brandacher G

1:30 pm 172KEAP1 SILENCING IMPROVES DIABETES-SPECIFIC DEFECTS INMESENCHYMAL STEM CELL FUNCTIONPresenter: Yee Cheng Low, MDAffiliation: NYU Medical CenterCo-Authors: Low YC; Ham MJ; Lotfi P; Wilson SC; Lalezarzadeh F; Ojo CO; SaadehPB; Ceradini DJ1:40 pm 173THE EFFECTS OF RADIATION THERAPY ON THE PROLIFERATION ANDDIFFERENTIATION OF ADIPOSE-DERIVED STEM CELLSPresenter: Yuan Liu, MDAffiliation: Cooper University HospitalCo-Authors: Jones R; Slotcavage R; Chang S; Carpenter J; Tulenko T1:50 pm 174PREDICTABLE AND DURABLE FAT GRAFTING BY TARGETED PROTECTION OFTHE DONOR MICROVASCULATURE USING PHOSPHODIESTERASE 5INHIBITORS (PDE5I)Presenter: Obi EzeamuzieAffiliation: NYU Medical CenterCo-Authors: Ezeamuzie O; Ojo CO; Ham MJ; Lalezarzardeh F; Lotfi P; Wilson SC;Saadeh PB; Ceradini DJ2:00 pm 175DELETION OF AXIN GENE IN MOUSE ADIPOSE-DERIVED STEM CELLS (MASCS)PROMOTES OSTEOGENESISPresenter: Masakazu Hasegawa, MD, PhDAffiliation: Stanford UniversityCo-Authors: Quarto N; Satoh K; Longaker MT2:10 pm 176CELL-ASSISTED LIPOTRANSFER WITH BONE MORPHOGENETIC PROTEINRECEPTOR IA+ ADIPOSE-DERIVED STROMAL CELL SUBPOPULATIONSPresenter: Kevin T Paik, A.B.Affiliation: Stanford UniversityCo-Authors: Chung MT, Hu MS, Lo DD, McArdle A, Hyun JS, Montoro DT, WalmsleyG, Senarath-Yapa K, Zimmermann AS, Sorkin M, Rennert R, Liu C, Chen HH, ChungAS, Longaker MT, Wan DC2:20 pm 177USE OF ADIPOSE DERIVED STEM CELLS FOR THE IMPROVEMENT OF BURNWOUND HEALINGPresenter: Anne Argenta, MDAffiliation: University of PIttsburgh Medical CenterCo-Authors: Satish L; Bliley J; McLauglin M; Marra K; Rubin JP2:30 pm 178TRANSCRIPTOMICS COMPARISON OF HUMAN-ADIPOSE DERIVED STEMCELLS DURING DIFFERENTIATIONPresenter: Brian Phillips, MDAffiliation: University of PittsburghCo-Authors: Krill-Burger M; Philips B; Gallo P; Des Estages S; Liu F; Ravuri S;Laframboise WA; Marra KG; Kathju S; Rubin JP

2:40 pm 179HUMAN MESENCHYMAL STEM CELLS REGENERATE MATURE BONE ANDMITIGATE INFLAMMATION IN A XENOTRANSPLANTATION MODELPresenter: Anisa Yalom, MDAffiliation: UCLA REBAR LabCo-Authors: Bueno DF; Li A; Buck A; Hokugo A; Zuk P; Nguyen P; Eduardo C; AmaralR; Bueno MRP; Jarrahy R2:50 pm 180ENHANCED ADIPOSE-DERIVED STROMAL CELL OSTEOGENESIS THROUGHSURFACE MARKER ENRICHMENT AND BMP MODULATIONPresenter: Michael T Chung,Affiliation: Stanford UniversityCo-Authors: Morrison SD, Liu C, Zimmermann AS, Paik KJ, Lo DD, Hyun JS, McArdleA, Walmsley G, Senarath-Yapa K, Montoro DT, Sorkin M, Rennert R, Hu M, Chen HH,Chung AS, Longaker MT, Wan DC3:00 pm 181NEURAL POTENTIAL OF THE STEM CELL POPULATION IN THE ADIPOSE ANDCUTANEOUS TISSUESPresenter: Ilaria Tocco Tussardi, MDAffiliation: Clinic of Plastic Surgery University Hospital of PaduaCo-Authors: Vindigni V; Bassetto F; Zavan B3:10 pm 182BONE MORPHOGENETIC PROTEIN RECEPTOR IB AS A MARKER FORENRICHMENT OF OSTEOGENIC PRECURSORSPresenter: Adrian McArdle, MDAffiliation: Stanford UniversityCo-Authors: Chung MT, Lo DD, Hyun JS, Montoro DT, Paik KJ, Walmsley G, Senarath-Yapa K, Zimmermann AS, Sorkin M, Rennert R, Hu M, Liu C, Chen HH, Chung AS,Longaker MT, Wan DC3:20 pm 183IDENTIFICATION OF A FUNCTIONALLY DISTINCT SUBPOPULATION OF HUMANADIPOSE DERIVED STEM CELLS USING SINGLE CELL TRANSCRIPTIONALANALYSISPresenter: Michael Sorkin, MDAffiliation: Stanford UniversityCo-Authors: Rennert R; Januszyk M; Chung MT; Longaker MT; Gurtner GC1:00 – 3:30 pm Session 10 Group C: Wound HealingModerator: TBDCo-Moderator: TBD1:00 pm 184ADIPOSE DERIVED-MESENCHYMAL STEM CELL SEEDED HYDROGELSACCELERATE CLOSURE OF MURINE WOUNDSPresenter: Ravi Garg, MDAffiliation: Stanford University and University of WisconsinCo-Authors: Rennert RC; Sorkin M; Auerbach LJ; Lennon J; Longaker MT; Gurtner GC1:10 pm 185

DYSREGULATION OF POST-TRANSLATIONAL COLLAGEN PATHWAYS MAYUNDERLIE HYPERTROPHIC AND KELOID PATHOPHYSIOLOGY: A ROLE FORTARGETED IMMUNOSUPPRESSION THERAPY?Presenter: Victor W Wong, MDAffiliation: Stanford UniversityCo-Authors: You F; Januszyk M; Gurtner GC; Kuang AA1:20 pm 186NORMALIZING DYSFUNCTIONAL PURINE METABOLISM IN THE DIABETICREGENERATIVE ENVIRONMENT ACCELERATES CUTANEOUS WOUNDHEALINGPresenter: Frank Lalezarzadeh, BSAffiliation: New York UniversityCo-Authors: Wilson SC; Weinsten AL; Soares MA; Ham MJ; Lotfi P; Ojo CO; SartorRA; Saadeh PB; Ceradini DJ1:30 pm 187TRANSIENT RECEPTOR POTENTIAL C3 PLAY AN IMPORTANT ROLE IN THEFORMATION OF HYPERTROPHIC SCAR AS A MECHANICAL TRANSDUCERPresenter: Hisako Ishise, MDAffiliation: Hyogo College of MedicineCo-Authors: Kawai K; Larson BJ; Nishimoto S; Kakibuchi M1:40 pm 188FIBROMODULIN INDUCES ANGIOGENESIS DURING CUTANEOUS WOUNDHEALINGPresenter: Jia Jian, PhDAffiliation: University of California Los AngelesCo-Authors: Zheng Z; Hsu CY; Velasco O; Zhang K; Wang J; Zhang X; Ting K; Soo C1:50 pm 189NOTCH SIGNALING IN THE OSTEOINDUCTION OF ADIPOSE-DERIVED STEMCELLS: A POSSIBLE THERAPEUTIC ROLE IN THE VIABILITY OF NON-VASCULARIZED BONE GRAFTSPresenter: Shaun D Mendenhall, MDAffiliation: Southern Illinois University School of MedicineCo-Authors: Lough D; Chambers CB; Bueno RA; Germann G; Reichensperger JD;Neumeister MW2:00 pm 190LOSARTAN AND TREATMENT OF SCAR CONTRACTURE: PRECLINICALSTUDIES INTO THE ROLE OF ANGIOTENSIN, ITS RECEPTORS AND EFFECT ONACTIN ISOFORM EXPRESSION IN SCAR CONTRACTURE.Presenter: Jennifer Bond, PhDAffiliation: Duke University Medical CenterCo-Authors: Ehanire T; Ren L; Levinson H2:10 pm 191SALVAGE OF INFECTED CARDIOVASCULAR IMPLANTABLE ELECTRONICDEVICES BY A NOVEL THERAPYPresenter: Moris Topaz, MD, PhD, FRCSCAffiliation: Hillel Yaffe Medical CenterCo-Authors: Kazatsker M; Oron Y; Keren G; Silberman A; Carmel NN; Topaz G; MeiselSR; Frimerman A; Blondheim DS; Shotan A

2:20 pm 192INSIGHTS INTO DIABETIC WOUND MICROCIRCULATION: A NOVEL IN VIVOMODELPresenter: Tanja Khosrawipour,Affiliation: Leipzig University HospitalCo-Authors: Dorfmann O; Ring A; Zeplin PH; Spindler N; Langer S2:30 pm 193THE ABERRANT NOTCH SIGNALING CONTRIBUTE TO SCAR HYPERPLASIATHROUGH MODULATING BIOACTIVITY OF KERATINOCYTESPresenter: Wei Xia, MD, MSAffiliation: Fourth Military Medical University Xijing HospitalCo-Authors: DIAO J; XIA W2:40 pm 194REAL-TIME INVESTIGATION OF THE ANGIOGENIC EFFECT OF DEFEROXAMINEON ENDOTHELIAL CELLS EXPOSED TO RADIOTHERAPYPresenter: Alexis Donneys, MD, MSAffiliation: University of MichiganCo-Authors: Deshpande SS; Levi B; Buchman SR2:50 pm 195INNOVATIVE ANALYTIC MORPHOMETRIC ASSESSMENT AND BODYCOMPOSITION PREDICTS SURGICAL SITE INFECTION IN PATIENTSUNDERGOING COMPONENT SEPARATION VENTRAL HERNIA REPAIRPresenter: Jeffrey L Lisiecki, ScBAffiliation: University of Michigan Medical SchoolCo-Authors: Levi B; Rinkinen JR; Terjimanian MN; Holcombe SA; Kozlow JH; WangSC; Kuzon WM3:00 pm 196BIOCHEMISTRY OF DAMAGE AND REPAIR IN BREAST CANCERRECONSTRUCTION FOLLOWING RADIOTHERAPYPresenter: Justin R Hubenak, BSAffiliation: MD AndersonCo-Authors: OConnor C; Kronowitz SJ3:10 pm 197PREDICTIVE FACTORS OF WOUND COMPLICATIONS FOLLOWING SARCOMARESECTION REQUIRING PLASTIC SURGEON INVOLVEMENTPresenter: Kyle Sanniec, MHA, MAAffiliation: Mayo Clinic ArizonaCo-Authors: Swanson S; Casey WJ; Schwartz A; Bryant L; Rebecca A3:20 pm 198NOVEL BIODEGRADABLE POLY ESTER-AMIDE (PEA) POLYMER COATINGSIGNIFICANTLY REDUCES SUTURE ASSOCIATED INFLAMMATORY RESPONSEPresenter: Tatiana Boyko, MDAffiliation: Weill Cornell Medical CollegeCo-Authors: Hernandez KA; Moody PW; van Harten MC; Reiffel AJ; van Koot JF; ChuCC; Harper A; Spector JA3:30 – 4:00 pm Coffee with Exhibitors4:00 – 5:30 pm Session 11 Group A: Tumor ImmunologyModerator: TBDCo-Moderator: TBD

4:00 pm 199HYPOXIA AS A MEDIATOR OF ADIPOKINE PRODUCTION IN PATIENTS AT RISKFOR BREAST CANCERPresenter: Irene Pien, BA, BSAffiliation: Duke University Medical CenterCo-Authors: Fisher M; Bond J; Lem S; Frye E; Suarez A; Ibarra-Drendall C; Klitzman B;Seewladt V; Hollenbeck ST4:10 pm 200GENE-DIRECTED ENZYME PRODRUG THERAPY (GDEPT) IN A HUMAN TUMORXENOGRAFT MODEL USING GENE-MODIFIED MUSCLE TISSUES ANDCHEMOTHERAPEUTIC PRODRUG MOLECULES.Presenter: Ergun Kocak, MDAffiliation: The Ohio State UniversityCo-Authors: Carruthers KH; Choi E; During MJ4:20 pm 201LYMPHEDEMA IS ASSOCIATED WITH A MARKED INCREASE OF TISSUE T-REGULATORY CELLSPresenter: Nicholas J Albano, StudentAffiliation: Memorial Sloan Kettering Cancer CenterCo-Authors: Ghanta S; Zampell JC; Weitman ES; Cuzzone DA; Aschen SZ; Farias-Eisner GT; Yan A; Mehrara BJ4:30 pm 202TELOMERE LENGTH WITHIN KELOIDS: NOVEL IMPLICATIONS FOR KELOIDPATHOGENESIS & TREATMENTPresenter: Lily Daniali, MDAffiliation: University of Medicine and Dentistry of New Jersey School of MedicineCo-Authors: Kimura M; Kim S; Cao X; Herbig U; Aviv A; Granick M4:40 pm 203A DISTINCT REGION OF MCL-1 DEFINES ITS ANTISENESCENT PROPERTIESPresenter: Simon E Schlager, StudentAffiliation: Case Western Reserve UniversityCo-Authors: Pfannenstiel LW; Demelash A; Maybruck B; Gastman BA4:50 pm 204A COMMON POLYMORPHISM WITHIN THE IGF2 IMPRINTING CONTROL REGIONIS ASSOCIATED WITH PARENT OF ORIGIN SPECIFIC EFFECTS IN INFANTILEHEMANGIOMASPresenter: Brent E Schultz, MBBS, PhD, FRACSAffiliation: University of WashingtonCo-Authors: Yao X; Deng Y; Waner M; Spock C; Tom L; Persing J; Narayan D5:00 pm 205UTILIZING THE SPY-ELITE SYSTEM TO IMPROVE IDENTIFICATION OFSENTINEL LYMPH NODES IN CUTANEOUS MELANOMAPresenter: Jason M Korn, MDAffiliation: Cleveland Clinic FoundationCo-Authors: Bartz-Kurycki MA; Gastman BR5:10 pm 206TUMOR-INDUCED, DYSFUNCTIONAL CD8+ T CELLS: IMPLICATIONS FORCANCER IMMUNOTHERAPYPresenter: Brian Gastman

Affiliation: Cleveland ClinicCo-Authors: Maybruck B;5:20 pm 207A SYNGENEIC IMMUNOCOMPETENT MURINE FIBROSARCOMA (BFS-1) MODELTO STUDY HOST DEFENSE-LIKE LYTIC PEPTIDE AND DOXORUBICINCOMBINATION THERAPYPresenter: Philip Suppelna, MDAffiliation: BG University Hospital BergmannsheilCo-Authors: Jacobsen F; Al- Benna S; Becerikli M; Merwart B; Rittig A; Stricker I;Lehnhardt M; Steinstraesser L4:00 – 5:30 pm Session 11 Group B: Craniofacial/BoneModerator: TBDCo-Moderator: TBD4:00 pm 208THE IN VITRO REGULATION OF OSTEOGENIC DIFFERENTIATION BYINFLAMMATORY CYTOKINESPresenter: Lauren L Zammerilla, BSAffiliation: University of PittsburghCo-Authors: Shakir S; Naran S; Cray JJ; Smith DM; Wang D; Losee JE; Cooper GM4:10 pm 209THE EFFECT OF OXYSTEROL ON OSTEOGENESIS IN HUMAN ADIPOSEDERIVED STEM CELLSPresenter: Patricia Zuk, PhDAffiliation: UCLA REBAR LabCo-Authors: Li A; Buck A; Hokugo A; Sorice S; Lee J; Jarrahy R4:20 pm 210CONTRIBUTION OF ORTHODONTIC DENTAL SPACE CLOSURE TO MAXILLARYHYPOPLASIA IN THE CLEFT PATIENTPresenter: Justine C Lee, MD, PhDAffiliation: UCLACo-Authors: Slack GC, Walker R; Martz MG; Graves L; Yen S; Woo J; Ambaram R;Kawamoto HK; Bradley JP4:30 pm 211OPTIMIZING THE TIMING AND TECHNIQUE OF TREACHER COLLINS ORBITALMALAR RECONSTRUCTIONPresenter: Christina Federico, BAAffiliation: UCLACo-Authors: Lee JC; Fan KL; Kawamoto HK; Bradley JP4:40 pm 212TENSILE STRESS WITH THE ABSENCE OF FRANK DISTRACTION CAN STILLPREVENT THE PHYSIOLOGICAL FUSION OF THE POSTERIOR FRONTALSUTURE IN THE RAT.Presenter: Niki E Springett, StudentAffiliation: Prince of Wales Hospital University of New South WalesCo-Authors: Oliver R; Peltz TS; Gianoutsos MP; Walsh WR4:50 pm 213

AMIFOSTINE PROPHYLAXIS CONFERS LONG-TERM BIOMECHANICALPROTECTION TO IRRADIATED BONEPresenter: Peter A Felice, MDAffiliation: University of Michigan School of MedicineCo-Authors: Ahsan S; Donneys A; Deshpande SS; Nelson NS; Perosky JE; KozloffKM; Buchman SR5:00 pm 214DEFEROXAMINE RESTORES BIOMECHANICAL PROPERTIES ANDPOTENTIATES UNION OF IRRADIATED BONE IN DISTRACTION OSTEOGENESISPresenter: Noah S Nelson, BSAffiliation: University of Michigan School of MedicineCo-Authors: Felice PA, Donneys A; Ahsan S; Deshpande SS; Perosky JE; Kozloff KM;Buchman SR5:10 pm 215NOGGIN AND CHORDIN KNOCKDOWN IN DISTRACTION OSTEOGENESIS : INVITRO STUDYPresenter: Priscille Grenier-Vallee, MDAffiliation: McGill University Shriners Hospital for ChildrenCo-Authors: Kasaai B; Moffatt P; Hamdy RC5:20 pm 216TEN-YEAR EXPERIENCE OF 36,000 OROFACIAL CLEFTS IN AFRICAPresenter: Julia C Conway, BAAffiliation: Mount Sinai School of MedicineCo-Authors: Jabs EW; Oberoi K; Doucette J; Taub PJ4:00 – 5:30 pm Session 11 Group C: NerveModerator: TBDCo-Moderator: TBD4:00 pm 217REDUCTION IN MUSCLE ATROPHY WITH THE USE OF SIDE-TO-SIDE NERVEBRIDGESPresenter: Jill Shea, DOAffiliation: University of UtahCo-Authors: Doner LJ; Garlick JW; Mendenhall SD; Agarwal JP4:10 pm 218NEUROPROTECTIVE EFFICACY OF AMINOPROPYL CARBAZOLES IN ANEONATAL RAT MODEL OF NERVE INJURYPresenter: Stephen W Kemp, PhDAffiliation: The Hospital for Sick Children University of TorontoCo-Authors: Pieper AA; Wood MD; Szynkaruk M; Liu EH; Gordon T; Borschel GH4:20 pm 219ALGORITHM DEVELOPMENT: SIGNIFICANT TIBIAL NERVE FASCICULARCONTRIBUTIONS TO LEG CONTROLPresenter: James Allison, BAAffiliation: University Of MichiganCo-Authors: Washabaugh EP; Moon JD; Kung TA; Langhals NB; Cederna PS;Urbanchek MG4:30 pm 220RECURRENT AND PERSISTENT CARPAL TUNNEL SYNDROME: A SYSTEMATICREVIEW OF THE LITERATURE AND 40-YEAR META-ANALYSIS.

Presenter: Ali M SoltaniAffiliation: University of MiamiCo-Authors: Allan BJ; Best MJ; Mir HS; Panthaki ZJ4:40 pm 221RESTORATION OF LONG NERVE DEFECTS WITH EPINEURAL SHEATHCONDUIT SUPPORTED WITH BONE MARROW STROMAL CELLS. APRELIMINARY REPORTPresenter: Maria Madajka, PhDAffiliation: Cleveland ClinicCo-Authors: Can Ozturk CO; MIroslaw Lukaszuk ML; Jacek Szopinski JS; VlodekSiemionow VS; Maria Siemionow MS; Grzegorz Kwiecien GK4:50 pm 222AXONAL REGENERATION OF INJURED PERIPHERAL NERVES FOLLOWINGINTRAVENOUS DELIVERY OF ADIPOSE TISSUE DERIVED STROMAL CELLSPresenter: Christine Radtke, MD, PhDAffiliation: Hannover Medical SchoolCo-Authors: Matthes SM; Janssen I; Reimers K; Kocsis JD; Vogt PM5:00 pm 223PERIPHERAL NERVE REGENERATION USING NOVEL BIOENGINEEREDNEUROGENIC PEPTIDE AMPHIPHILE NANOFIBERS: PRELIMINARY IN-VITRODATAPresenter: Andrew Li, MDAffiliation: UCLA REBAR LabCo-Authors: Buck A; Hokugo A; Stupp S; Jarrahy R5:10 pm 224SELECTIVE ENHANCEMENT OF AXONAL INGROWTH IN PROCESSED NERVEALLOGRAFTS LOADED WITH NEUROTROPHIC FACTORS IN THE RAT SCIATICNERVE MODELPresenter: Richard B Boyer, Medical StudentAffiliation: Vanderbilt University School of MedicineCo-Authors: Sexton KW; Rodriguez-Feo CL; Pollins AC; Cardwell NL; Nanney LB;Shack RB; Thayer WP5:20 pm 225PRESERVING NIPPLE SENSATION IN BREAST REDUCTION SURGERY:ANATOMICAL AND CLINICAL STUDYPresenter: Saeed Chowdhry, BSAffiliation: University of LouisvilleCo-Authors: Brooks R; Kelishadi SS; Tutela JP; Wilhelmi BJ5:30 – 6:00 pm Awards Announcements & Adjourn