H. pylori

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H. Pylori associated specific diseasescont..Gastric ulcers(a premodern disease)• Associated with H.pylori-induced pan- or corpuspredominantgastritis with normal or reduced acidlevels• Ulcers usually arise at the junction of the antral andcorpus mucosa (an area of intense inflammation)• Occurs in old age
H. Pylori associated specific diseasescont..Duodenal ulcers(a premodern disease)• Arise on a background of H. pylori- induced antralgastritis• Antral gastritis hyperigastrinaemia & high levels ofacid production from healthy gastric corpusgastricmetaplasia of the duodenum colonization byH. pylori inflammation & ulceration• Occurs in middle age
Page 2 and 3: Shortly after enactment, the Califo
Page 5 and 6: H.pylori and humans: an ancientrela
Page 8: Human immune response toH. pylori
Page 11: H. Pylori associated specific disea
Page 15 and 16: Smoking?↑H.pylori virulence?Chang
Page 17 and 18: Absence of H. pylori: A risk factor
Page 19 and 20: Is this recent change in homeostati
Page 21 and 22: Absence of H. pylori causeshyperchl
Page 23 and 24: Absence of H. pylori : does thiscon
Page 25 and 26: Absence of H. pylori: contributes t
Page 29 and 30: Thank you!
Page 31: References:1. Atherton J.C. and Bla
Page 37: Phylogeography of H.PyloriLinz, B.,

H. pylori

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