H. pylori
H. pylori
H. pylori
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Absence of H. <strong>pylori</strong> causeshyperchlorhydria GORD• H. <strong>pylori</strong> causes Pan/corpus gastritis• causes atrophy and hypochlorhydria• is more common & likely ancient: considered „normal‟ forhumans• Thus, H. <strong>pylori</strong> negative persons• Results abnormally high acid output• If these persons have• a hiatus hernia,• a lax lower oesophageal sphincter, or• increased transient lower oesophageal sphincter relaxationsgastroesophageal refluxate will be acidic leading toGORD
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