23.11.2012 Views

Annual 2006 - Hauptman Woodward Institute - University at Buffalo

Annual 2006 - Hauptman Woodward Institute - University at Buffalo

Annual 2006 - Hauptman Woodward Institute - University at Buffalo

SHOW MORE
SHOW LESS

Create successful ePaper yourself

Turn your PDF publications into a flip-book with our unique Google optimized e-Paper software.

The <strong>Hauptman</strong>-<strong>Woodward</strong> Medical Research <strong>Institute</strong> (HWI) is an independent, not-for-profit,<br />

biomedical research facility loc<strong>at</strong>ed in the heart of downtown on the <strong>Buffalo</strong> Niagara Medical<br />

Campus. We are a founding member of the Campus together with our neighbors Roswell Park<br />

Cancer <strong>Institute</strong>, Kaleida, <strong>University</strong> <strong>at</strong> <strong>Buffalo</strong>, and the <strong>Buffalo</strong> Medical Group. For more than half a<br />

century, HWI scientists have been committed to improving human health through study, <strong>at</strong> the molecular<br />

level, of the causes and potential cures of many diseases. In contrast to clinical research, the focus<br />

of <strong>Hauptman</strong>-<strong>Woodward</strong>’s basic research is to determine the structures of individual substances such<br />

as proteins th<strong>at</strong> play a role in life’s processes and the development of specific diseases.<br />

Working under the leadership of Nobel Laure<strong>at</strong>e Herbert <strong>Hauptman</strong>, HWI scientists use the techniques<br />

of molecular biology, biochemistry, and crystallography to promote the understanding, tre<strong>at</strong>ment and<br />

prevention of specific human diseases, to aid in r<strong>at</strong>ional drug design, and to train research scientists. In<br />

addition, other research on-going <strong>at</strong> HWI seeks to improve the methods of crystalliz<strong>at</strong>ion and d<strong>at</strong>a<br />

analysis used for molecular structure determin<strong>at</strong>ion by scientists worldwide.<br />

Inside …<br />

President’s Message<br />

Chief Executive Officer’s Message<br />

Audited Financial St<strong>at</strong>ements<br />

<strong>Hauptman</strong>-<strong>Woodward</strong> Medical Research <strong>Institute</strong>, Inc.<br />

<strong>Hauptman</strong>-<strong>Woodward</strong> Found<strong>at</strong>ion<br />

The Faces of Science<br />

On <strong>Hauptman</strong>-<strong>Woodward</strong>’s Boards<br />

At <strong>Hauptman</strong>-<strong>Woodward</strong><br />

Our Dedic<strong>at</strong>ed Donors<br />

Select Public<strong>at</strong>ions<br />

<strong>2006</strong> ANNUAL REPORT


PRESIDENT’S MESSAGE .... CHIEF EXECUTIVE OFFICER’S MESSAGE ...<br />

Passion pushes progress. Hyp<strong>at</strong>ia, the philosopher, astronomer and m<strong>at</strong>hem<strong>at</strong>ician paid<br />

the ultim<strong>at</strong>e price for her passion and yet her teachings lived on. The daughter of Theon of<br />

Alexandria, a teacher of m<strong>at</strong>hem<strong>at</strong>ics with the Museum of Alexandria in Egypt, Hyp<strong>at</strong>ia<br />

studied with her f<strong>at</strong>her, and with many others including Plutarch the Younger. She herself<br />

taught <strong>at</strong> the Neopl<strong>at</strong>onist school of philosophy where she l<strong>at</strong>er was the salaried director.<br />

She probably wrote on m<strong>at</strong>hem<strong>at</strong>ics, astronomy and philosophy, including on the motions<br />

of the planets, about number theory and about conic sections. She corresponded with and<br />

hosted scholars from other cities. She was a popular lecturer, drawing students from many<br />

parts of the Greek empire.<br />

From the little historical inform<strong>at</strong>ion about Hyp<strong>at</strong>ia th<strong>at</strong> survives, it appears th<strong>at</strong> she invented<br />

the plane astrolabe, the gradu<strong>at</strong>ed brass hydrometer and the hydroscope. She dressed in the<br />

clothing of a scholar, r<strong>at</strong>her than in women's clothing and moved about freely, driving her<br />

own chariot, contrary to the norm for women's public behavior. She exerted considerable<br />

political influence in the city.<br />

The new Christian bishop, Cyril, a future saint objected to Hyp<strong>at</strong>ia on a number of counts: she represented heretical<br />

teachings, including experimental science and pagan religion. And she was a woman who didn't know her place. Cyril's<br />

preaching against Hyp<strong>at</strong>ia is said to have been wh<strong>at</strong> incited a mob led by fan<strong>at</strong>ical Christian monks to <strong>at</strong>tack her as she<br />

drove her chariot through Alexandria. They dragged her from her chariot, stripped her, killed her, stripped her flesh from<br />

her bones, sc<strong>at</strong>tered her body parts through the streets, and burned some remaining parts of her body in the library of<br />

Caesareum. Her students fled to Athens, where the study of m<strong>at</strong>hem<strong>at</strong>ics flourished.<br />

Hyaptia’s passion for the sciences and m<strong>at</strong>hem<strong>at</strong>ics was unorthodox <strong>at</strong> th<strong>at</strong> time. She pushed the boundaries and she<br />

was fueled by her passion and she paid the ultim<strong>at</strong>e price.<br />

Our scientists too are driven by a passion – the passion to achieve a gre<strong>at</strong>er understanding of our science. They too make<br />

sacrifices for their passion and I continue to be awed and impressed by the commitment of time, energy and cre<strong>at</strong>ivity our<br />

scientific and non-scientific staff brings to the table each day as they try to advance their science and build the strength<br />

and success of <strong>Hauptman</strong>-<strong>Woodward</strong>. You will meet each of these terrific HWI employees on the following pages.<br />

As most of you probably know by now, our current CEO, George DeTitta, is making his choice to return next year fulltime<br />

to his truest passion by returning to his lab. I commend him for the leadership he has provided the <strong>Institute</strong> during<br />

his tenure and I commend him for having the conviction to be where his passion lies – in the lab. George’s leadership<br />

will leave a legacy and a found<strong>at</strong>ion which the succeeding CEO can build upon for future, and perhaps, even gre<strong>at</strong>er<br />

successes supported by the stable core of scientists and staff members who are the fabric of this facility.<br />

Of course, I would be remiss not to acknowledge the passion th<strong>at</strong> drives our friends and donors to continue to support us<br />

in our effort to succeed and not simply survive. To our core supporters, I thank you on behalf of the <strong>Institute</strong> because you<br />

too play an essential role in improving human health.<br />

The combined passion of our scientists, our staff, our leaders, current and future, and our stalwart supporters also will<br />

push our continuing progress for many tomorrows to come.<br />

Herbert A. <strong>Hauptman</strong>, Ph.D., Nobel Laure<strong>at</strong>e<br />

President<br />

The ties th<strong>at</strong> bind us and the passion th<strong>at</strong> inspires us …<br />

I have often heard Herb speak about how his passion for science and m<strong>at</strong>h began as a<br />

very young child … I have heard some of the young scientists reminisce about how their<br />

curiosity has made the lab their second home … I have listened to our CFO discuss<br />

balance sheets with a level of excitement only known to accountants … I have observed<br />

our other support staff be wrapped up in a love of wh<strong>at</strong> they do and I know myself th<strong>at</strong><br />

it is a love of wh<strong>at</strong> I do in the lab and the immense respect and appreci<strong>at</strong>ion I have for<br />

my colleagues th<strong>at</strong> draws me to the lab each day.<br />

And it is th<strong>at</strong> drive and curiosity about how we can do it better and the discoveries th<strong>at</strong><br />

we can make to improve our science th<strong>at</strong> has further strengthened my resolve to complete<br />

my term as HWI CEO as of April 1, 2008.<br />

It has been an eventful and wonderful ride in the CEO chair during a time of gre<strong>at</strong><br />

change and growth, and I am honored to have led and to continue to lead such a<br />

tremendously talented and dedic<strong>at</strong>ed group of staff members – scientists and nonscientists<br />

alike.<br />

I will approach the next year with the same outlook as my entire time in office – I will be<br />

mentor, manager and ultim<strong>at</strong>e decision-maker for this organiz<strong>at</strong>ion until I formally hand<br />

over the reins to my yet-to-be-chosen successor. I will enjoy this last year as HWI CEO<br />

and then on April 1, 2008, I will happily enjoy returning full-time to my science.<br />

I hope each of you will approach the next year with th<strong>at</strong> same interactive and mutually<br />

supportive spirit which has brought us into the second 50 years of our existence. Our<br />

scientists, administr<strong>at</strong>ors, board members and community backers – I thank you for the<br />

past year and invite you to reinvigor<strong>at</strong>e your passion for HWI so we can firmly position<br />

our science <strong>at</strong> the forefront of our field for the foreseeable future. I look forward to our<br />

continued work together in the pursuit of scientific discovery. Whether you are growing<br />

proteins, crystallizing them, developing new and better methods to do our science,<br />

doing one of the many jobs th<strong>at</strong> help make it possible for all of the scientists to focus on<br />

the work in their labs, serving as a community ambassador or helping fund this critical<br />

work – you are an essential part of this process. Thank you.<br />

Sincerely,<br />

George DeTitta, Ph.D.<br />

Chief Executive Officer and Executive Director


FINANCIAL STATEMENTS<br />

HAUPTMAN-WOODWARD MEDICAL RESEARCH INSTITUTE<br />

STATEMENT OF FINANCIAL POSITION *<br />

OCTOBER 31, <strong>2006</strong><br />

ASSETS<br />

Current assets:<br />

Cash $ 149,763<br />

Pledges receivable, net 2,052,098<br />

Grants receivable-capital campaign 222,286<br />

Grants receivable-science 743,621<br />

Prepaid Expense 30,054<br />

Total current assets 3,197,822<br />

Investments: 5,652,468<br />

Fixed assets:<br />

Land, building and equipment, net 23,831,185<br />

Construction in progress 367,000<br />

24,198,185<br />

Other assets:<br />

Pledges receivable, net 1,491,681<br />

Deferred financing fees, net 706,305<br />

Assets held in charitable trust 356,824<br />

Swap contract 36,416<br />

Interest in net assets of <strong>Hauptman</strong>-<strong>Woodward</strong> Found<strong>at</strong>ion 163,345<br />

2,754,571<br />

Total assets $35,803,046<br />

LIABILITIES AND NET ASSETS<br />

Current liabilities:<br />

Accounts payable - oper<strong>at</strong>ing $ 503,407<br />

Accounts payable - construction-in-progress 148,000<br />

Accrued payroll and rel<strong>at</strong>ed taxes 149,408<br />

Refundable advances 24,054<br />

Capital lease oblig<strong>at</strong>ions -<br />

Bonds payable - current portion 185,000<br />

Total current liabilities 1,009,869<br />

Bonds payable 6,600,000<br />

Total liabilities 7,609,869<br />

Net assets:<br />

Unrestricted 20,679,637<br />

Unrestricted-design<strong>at</strong>ed 200,000<br />

Temporarily restricted 6,580,297<br />

Permanently restricted 733,243<br />

Total net assets 28,193,177<br />

Total liabilities and net assets $35,803,046<br />

* This inform<strong>at</strong>ion has been taken from the audited financial st<strong>at</strong>ements of<br />

<strong>Hauptman</strong>-<strong>Woodward</strong> Medical Research <strong>Institute</strong> for the fiscal year ending October 31, <strong>2006</strong><br />

HAUPTMAN-WOODWARD FOUNDATION<br />

STATEMENT OF FINANCIAL POSITION *<br />

OCTOBER 31, <strong>2006</strong><br />

ASSETS<br />

Current assets: $ 106,753<br />

Pledges receivable, net 52,913<br />

Prepaid Expense 1,300<br />

Total current assets 160,966<br />

Investments 21,273<br />

Total assets $182,239<br />

LIABILITIES AND NET ASSETS<br />

Current liabilities:<br />

Accounts payable $ 17,313<br />

Accrued payroll and rel<strong>at</strong>ed taxes 1,581<br />

Total current liabilities 18,894<br />

Net assets:<br />

Unrestricted 128,086<br />

Temporarily restricted 35,259<br />

Total net assets 163,345<br />

Total liabilities and net assets $ 182,239<br />

* This inform<strong>at</strong>ion has been taken from the audited financial st<strong>at</strong>ements of<br />

<strong>Hauptman</strong>-<strong>Woodward</strong> Found<strong>at</strong>ion for the fiscal year ending October 31, <strong>2006</strong>


THE FACES OF SCIENCE AT HWI BOARD OF DIRECTORS AND OFFICERS<br />

“Our unique environment, intern<strong>at</strong>ional reput<strong>at</strong>ion and st<strong>at</strong>e-ofthe-art<br />

biomedical research facility have enabled us to consistently<br />

<strong>at</strong>tract outstanding scientific talent to HWI. In fact, we are<br />

in the enviable position of always having an overabundance of<br />

top-notch candid<strong>at</strong>es who want to work <strong>at</strong> HWI. It is these future<br />

HWI scientists, in collabor<strong>at</strong>ion with our current scientists who will<br />

ensure our continued success. Our scientists, and staff members<br />

are the true found<strong>at</strong>on of this institute.” ~ George T. DeTitta, Ph.D.<br />

The People of the <strong>Hauptman</strong>-<strong>Woodward</strong> Medical Research <strong>Institute</strong><br />

Our gre<strong>at</strong>est assets are our people. <strong>Hauptman</strong>-<strong>Woodward</strong> is fortun<strong>at</strong>e to be home to some of the<br />

most cre<strong>at</strong>ive minds in science today and has the distinction of offering an investig<strong>at</strong>or-initi<strong>at</strong>ed<br />

approach th<strong>at</strong> allows our scientists to transl<strong>at</strong>e their passion for their work into their everyday experiences.<br />

The scientific team is supported daily by talented individuals who serve on our boards and a<br />

staff which includes individuals with a wide range of talents and experiences. Each employee <strong>at</strong><br />

<strong>Hauptman</strong>-<strong>Woodward</strong> plays a role in ensuring the organiz<strong>at</strong>ion’s current and future successes.<br />

Donald A. Hess<br />

Chairman of the Board<br />

Paul J. Koessler<br />

Vice Chairman of the Board<br />

Christopher T. Greene<br />

Chairman of the Found<strong>at</strong>ion Board<br />

Elizabeth S. Mitchell<br />

Vice Chairman of the Found<strong>at</strong>ion Board<br />

Board of Directors and Officers<br />

Donald A. Hess<br />

(Chairman)<br />

Paul J. Koessler<br />

(Vice Chairman)<br />

Herbert A. <strong>Hauptman</strong>, Ph.D.<br />

(President)<br />

George T. DeTitta, Ph.D.<br />

(Executive Director and CEO)<br />

Walter A. Pangborn, Ph.D.<br />

(Executive Vice President)<br />

James R. Biltekoff<br />

(Treasurer and Chairman,<br />

Finance Committee)<br />

Elizabeth S. Mitchell<br />

(Secretary)<br />

Lisa Foti Milk, CPA<br />

(CFO and Assistant Treasurer)<br />

Adelbert Fleischmann<br />

(Co-Counsel)<br />

Michele O. Heffernan<br />

(Co-Counsel)<br />

Cynthia Ambres, M.D.<br />

Richard Aubrecht<br />

Norbert A. Bennett<br />

Alan L. Dressler<br />

Robert Glenning<br />

Christopher T. Greene<br />

David C. Hohn, M.D.<br />

Robert J. A. Irwin<br />

William L. Joyce<br />

Elizabeth C. Marks<br />

Anthony M. Masiello<br />

Lewis D. McCauley<br />

Peter T. Ostrow, M.D., Ph.D.<br />

P<strong>at</strong>rick Reilly<br />

Richard W. Shaughnessy<br />

Walter F. Stafford, III, Ph.D.<br />

Andrew M. Gulick, Ph.D.<br />

(Chairman,Scientific Governance Council)<br />

Found<strong>at</strong>ion Board<br />

Christopher T. Greene<br />

(Chairman)<br />

Elizabeth S. Mitchell<br />

(Vice Chairman)<br />

George T. DeTitta, Ph.D.<br />

(Executive Director and CEO)<br />

Elizabeth C. Marks<br />

(Secretary)<br />

James R. Biltekoff<br />

(Treasurer)<br />

Jennifer J. Daniels<br />

Nancy L. Dowdell<br />

Alan L. Dressler<br />

Christopher G. Gibas<br />

Jane F. Griffin, Ph.D.<br />

Eva M. Hassett<br />

Herbert A. <strong>Hauptman</strong>, Ph.D.<br />

Donald A. Hess<br />

Paul J. Koessler<br />

Richard W. Shaughnessy<br />

Emeritus Directors<br />

Alan P. Bagley<br />

Thomas R. Beecher Jr.<br />

Constance S. Constantine<br />

James R. Kanski, M.D.<br />

Charles A. Martin, Jr.<br />

Donald F. Newman<br />

Albert J. Wright, III


LEADERSHIP<br />

Herbert A. <strong>Hauptman</strong>, Ph.D.<br />

Position: Principal Research Scientist & President<br />

Appointments: He is a Distinguished Professor in the UB Department of Structural Biology, an Adjunct Professor in UB’s<br />

Department of Computer Science and Engineering, and a Research Professor in the UB Department of Biophysical<br />

Sciences.<br />

Research: As a m<strong>at</strong>hem<strong>at</strong>ician, Dr. <strong>Hauptman</strong> is interested in the development of m<strong>at</strong>hem<strong>at</strong>ical methods to determine the<br />

structures of biologically important substances. His current work builds on his Nobel-winning 'direct methods' research.<br />

Current projects are extending the methods of structure determin<strong>at</strong>ion to macromolecules, such as proteins, th<strong>at</strong> are<br />

models for drug design, and the extension of his methods from traditional X-ray diffraction to the advanced technique of<br />

neutron diffraction. A computer program, SnB, has been developed and continues to be refined. Dr. <strong>Hauptman</strong> also<br />

spends time mentoring and educ<strong>at</strong>ing others locally and globally about science and basic biomedical research.<br />

Educ<strong>at</strong>ion: Received his B.S., M.A., and Ph.D. in M<strong>at</strong>hem<strong>at</strong>ics from the City College of New York, Columbia <strong>University</strong>,<br />

and the <strong>University</strong> of Maryland, respectively.<br />

Noteworthy Contributions: Dr. <strong>Hauptman</strong> received the Nobel Prize in Chemistry in 1985 for his development of the<br />

m<strong>at</strong>hem<strong>at</strong>ical technique known as “direct methods.” He is a member of the N<strong>at</strong>ional Academy of Sciences since 1988<br />

and has received the City of <strong>Buffalo</strong>’s 1995 Citizen of Distinction, Western New York Man of the Year Award from the<br />

<strong>Buffalo</strong> Chamber of Commerce in 1986, and Citizen of the Year Award from the <strong>Buffalo</strong> Evening News in 1986. In<br />

addition, he has received honorary degrees from 11 colleges and universities around the world. Most recently, <strong>Hauptman</strong><br />

received a prestigious grant from The Intern<strong>at</strong>ional Human Frontier Science Program Organiz<strong>at</strong>ion (HFSPO) for<br />

a multin<strong>at</strong>ional, multidisciplinary project researching neutron diffraction. The grant is so prestigious than only a handful<br />

of projects are even invited to apply – and of the 54 accepted applic<strong>at</strong>ions, this project was ranked number one.<br />

George T. DeTitta, Ph.D.<br />

Position: Principal Research Scientist, Executive Director &<br />

Chief Executive Officer<br />

Appointments: He is a Professor and Department Chair for<br />

the <strong>University</strong> <strong>at</strong> <strong>Buffalo</strong>’s Department of Structural Biology, a<br />

Research Professor in the Department of Chemistry <strong>at</strong> UB, and<br />

a member of the Molecular and Cell Biology Department &<br />

Pharmacology and Experimental Therapeutics Department <strong>at</strong><br />

the Roswell Park Cancer <strong>Institute</strong>.<br />

Research: Current research focuses on the macromolecular<br />

crystalliz<strong>at</strong>ion problem and the development of innov<strong>at</strong>ive methods<br />

and techniques to improve crystal growth. Dr. DeTitta also<br />

spends time focusing on the growth of the medical research<br />

efforts <strong>at</strong> HWI and in Western New York, and on initi<strong>at</strong>ing<br />

collabor<strong>at</strong>ive projects with scientists <strong>at</strong> several local institutions.<br />

Educ<strong>at</strong>ion: Dr. DeTitta received his B.S. in Chemistry from Villanova <strong>University</strong> and his Ph.D. in Crystallography and<br />

Biochemistry from the <strong>University</strong> of Pittsburgh.<br />

Noteworthy Contributions: He has been directly involved in projects with NASA and is co-inventor of two p<strong>at</strong>ented<br />

devices for growing crystals. His team’s most recent high throughput robotics work has earned them partnerships in<br />

two genomics consortium, Northeast Structural Genomics and Structural Genomics of P<strong>at</strong>hogenic Protozoa. His work<br />

in the crystal growth arena has earned him worldwide recognition spurring invited speaking engagements within the<br />

U.S. and abroad. In 2005, his lab earned a $17.1 million NIH grant to fund a Center for High-Throughput Structural<br />

Biology, making his lab one of ten n<strong>at</strong>ionally funded centers th<strong>at</strong> are part of the N<strong>at</strong>ional <strong>Institute</strong>s of General Medical<br />

Sciences Protein Structure Initi<strong>at</strong>ive.<br />

Walter A. Pangborn, Ph.D.<br />

Position: Principal Research Scientist & Executive Vice President<br />

Appointments: He is an Associ<strong>at</strong>e Professor in the Department of<br />

Structural Biology <strong>at</strong> the <strong>University</strong> <strong>at</strong> <strong>Buffalo</strong>.<br />

Research: Dr. Pangborn is currently involved in X-ray diffraction<br />

analysis and d<strong>at</strong>a collection of crystal structures using X-ray Area<br />

Detectors. His d<strong>at</strong>a collection and analysis work encompasses<br />

proteins, steroids, killer toxins and antibiotics rel<strong>at</strong>ed to many<br />

diseases. Dr. Pangborn headed the efforts for the construction of our<br />

new research facility. Also, he is involved in the design and construction<br />

of a beam-line simul<strong>at</strong>or in the x-ray diffraction labor<strong>at</strong>ory.<br />

Educ<strong>at</strong>ion: He received his B.S. in Chemistry from Providence<br />

College and his Ph.D. in Biophysics from the <strong>University</strong> of Maryland,<br />

School of Medicine.<br />

Noteworthy Contributions: Public<strong>at</strong>ions include more than 190 papers, abstracts, and chapters. He also collabor<strong>at</strong>es<br />

with several organiz<strong>at</strong>ions across the United St<strong>at</strong>es including the Stanford Synchrotron Research Labor<strong>at</strong>ory and the<br />

Cornell High Energy Synchrotron Source.


DISTINGUISHED & PRINCIPAL RESEARCH SCIENTISTS<br />

Vivian Cody, Ph.D.<br />

Position: Principal Research Scientist<br />

Appointments: At the <strong>University</strong> <strong>at</strong> <strong>Buffalo</strong>, Dr. Cody is a Professor in the Department of Structural Biology, a Research<br />

Professor of Medicine, School of Medicine, an Associ<strong>at</strong>e Research Professor, Department of Molecular and Cellular-<br />

Biophysics and Biochemistry, Roswell Park Gradu<strong>at</strong>e Division.<br />

Research: Dr. Cody’s research focuses on cancer, thyroid disorders, and AIDS-rel<strong>at</strong>ed diseases. More specifically, she<br />

uses X-ray crystallography and computer graphics methods to determine molecular details of protein crystals. This allows<br />

new anticancer and antipneumocystis agents to be developed to fight P.c. pneumonia. She also investig<strong>at</strong>es the molecular<br />

level details of thyroid hormone function.<br />

Educ<strong>at</strong>ion: She received her B.S. and Ph.D. in Chemistry from the <strong>University</strong> of Michigan and the <strong>University</strong> of Cincinn<strong>at</strong>i,<br />

respectively.<br />

Noteworthy Contributions: Her public<strong>at</strong>ions include more than 500 papers, abstracts, chapters, books, and reviews.<br />

She has been a member of HWI’s staff since 1970 and is a leader in Zonta Intern<strong>at</strong>ional, a women’s service organiz<strong>at</strong>ion.<br />

She was secretary of the American Crystallographic Associ<strong>at</strong>ion, 1988-94, on the Advisory Committee for<br />

<strong>University</strong> of North Carolina GRIP Molecular Graphics Research Resource,1990-1999, on the subcommittee for the<br />

American <strong>Institute</strong> of Physics Congressional Fellowship Selection 1991-1997 and served as chairman, 1994-1997.<br />

She also served on the Editorial Board for Endocrinology 1993-2000, received an Award for Western New York<br />

Health Care Technology/ Discovery, 1994, editor, J. Molecular Graphics, 1995-1998, received the Award for New<br />

York St<strong>at</strong>e Sen<strong>at</strong>e, Woman of Distinction 2001, received the YWCA Leadership Award-Professions, 2002, Editorial<br />

Board Member, Journal of Biological Chemistry, July 2003-2008, Erie County Woman of Distinction, Women’s<br />

History Month Billboard, March 2003, member of ADDT Study Section, June 2004-2008, Women of Achievement,<br />

2004 <strong>Buffalo</strong> Chapter American Associ<strong>at</strong>ion of <strong>University</strong> Women, and also received the <strong>University</strong> <strong>at</strong> <strong>Buffalo</strong><br />

Sustained Achievement Award, 2005.<br />

William L. Duax, Ph.D.<br />

Position: H.A. <strong>Hauptman</strong> Distinguished Scientist<br />

Appointments: Dr. Duax is a Professor in the Department of Structural<br />

Biology <strong>at</strong> the <strong>University</strong> <strong>at</strong> <strong>Buffalo</strong>.<br />

Research: Dr. Duax’s current research is on the areas of bioinform<strong>at</strong>ics,<br />

proteomics, and genomics. He is predicting the structure<br />

and function of 5000 hypothetical genes th<strong>at</strong> are members of the<br />

steroid dehydrogenase family. Members of th<strong>at</strong> family of enzymes<br />

are implic<strong>at</strong>ed in the etiology of cancer, high blood pressure,<br />

Alzheimer’s disease, artherosclerosis, and polycystic kidney<br />

disease. Through analysis of the system of these 5000 proteins and<br />

the genes th<strong>at</strong> express them, he is tracing the evolution of the<br />

genetic code to its origin over three billion years ago. He is testing<br />

his predictions using the technique he applied in the past to determine<br />

the molecular basis for the action of hormone drugs and<br />

antibiotics.<br />

Educ<strong>at</strong>ion: He received his B.A. in Chemistry from St. Ambrose College and his Ph.D. in Physical Chemistry from the<br />

<strong>University</strong> of Iowa.<br />

Noteworthy Contributions: Dr. Duax is a recipient of MERIT (Method of Extended Research in Time) Award from the<br />

N<strong>at</strong>ional <strong>Institute</strong>s of Health from 1987 to 1995. He also received the Distinguished Scientific Award from the Clinical<br />

Ligand Society in 1995 and an honorary degree from the <strong>University</strong> of Lodz in Poland in 1999. He has been an<br />

invited lecturer <strong>at</strong> more than 180 universities, meetings, institutions, and conferences. His research also has uncovered<br />

the mystery of how licorice increases blood pressure with hopes to use this knowledge to find new ways to fight the<br />

disease. He has written more than 270 public<strong>at</strong>ions, 56 chapters and written or edited four books. He is past president<br />

of the Intern<strong>at</strong>ional Union of Crystallography (IUCr), an organiz<strong>at</strong>ion of more than 15,000 crystallographers throughout<br />

the world and is the founding editor of the quarterly newsletter of the IUCr<br />

Jane F. Griffin, Ph.D.<br />

Position: Principal Research Scientist and Director of Summer<br />

Internship Program<br />

Appointments: Dr. Griffin is an Associ<strong>at</strong>e Professor in the <strong>University</strong><br />

<strong>at</strong> <strong>Buffalo</strong>’s Structural Biology Department.<br />

She sits on several boards including the Western New York Technology<br />

Development Center (INSYTE) and Holy Angels Academy.<br />

Research: Research interests include the structure function rel<strong>at</strong>ionships<br />

in steroids and opi<strong>at</strong>es and the use of crystallographic d<strong>at</strong>abases<br />

in scientific studies.<br />

Educ<strong>at</strong>ion: Dr. Griffin received her B.A. in Chemistry from<br />

D’Youville College and her Ph.D. in Chemistry from the <strong>University</strong><br />

<strong>at</strong> <strong>Buffalo</strong><br />

Noteworthy Contributions: In 1996, she was honored with the Distinguished Alumni Award from the <strong>University</strong> <strong>at</strong> <strong>Buffalo</strong>.<br />

In addition to serving as Treasurer of the American Crystallographic Associ<strong>at</strong>ion (ACA) from 1995 to 2001, she received the<br />

ACA Service Award in 1991. She leads a Political Action Committee which is devoted to promoting and supporting women<br />

who run for political office on a local and st<strong>at</strong>e level. She previously headed the Molecular Biophysics Department <strong>at</strong> HWI.


SENIOR RESEARCH SCIENTISTS<br />

Robert H. Blessing, Ph.D.<br />

Position: Senior Research Scientist<br />

Appointments: Dr. Blessing holds two positions <strong>at</strong> the <strong>University</strong> <strong>at</strong> <strong>Buffalo</strong>, Professor in the<br />

Department of Structural Biology and Research Professor in the Department of Chemistry.<br />

He is also Director of Gradu<strong>at</strong>e Studies in the Structural Biology Department.<br />

Research: Dr. Blessing’s research focuses on experimental and comput<strong>at</strong>ional techniques<br />

for <strong>at</strong>taining high accuracy in both crystallographic diffraction measurements and<br />

crystal structure analyses. His interests include electron density distributions and chemical<br />

bonding in molecules and crystals and the crystallographic phase problem.<br />

Educ<strong>at</strong>ion: He received his B.S. in Chemistry from King’s College and his Ph.D. in<br />

Inorganic and Physical Chemistry from Ohio <strong>University</strong>.<br />

Noteworthy Contributions: Dr. Blessing has been an invited lecturer <strong>at</strong> universities in<br />

Denmark, France, Germany, Ireland, Italy and Spain. His public<strong>at</strong>ions include more<br />

than 130 abstracts, reviews, chapters, and peer-reviewed research papers.<br />

Daniel T. Gewirth, Ph.D.<br />

Position: Senior Research Scientist<br />

Appointments: He is an Associ<strong>at</strong>e Professor in the Department of Structural Biology <strong>at</strong><br />

the <strong>University</strong> <strong>at</strong> <strong>Buffalo</strong>.<br />

Research: Dr. Gewirth is interested in structural studies of Hsp90 chaperones, drug<br />

design, protein folding; nuclear hormone receptors and basal transcription factors.<br />

Educ<strong>at</strong>ion: He received his B.S. in Chemistry from the <strong>University</strong> of Chicago and<br />

earned his Ph.D. in Molecular Biophysics and Biochemistry from Yale <strong>University</strong>.<br />

Noteworthy Contributions: Dr. Gewirth’s public<strong>at</strong>ions include more than 20 papers<br />

and reviews.<br />

Debashis Ghosh, Ph.D.<br />

Position: Senior Research Scientist<br />

Appointments: He is an Associ<strong>at</strong>e Professor in the Department of Molecular and<br />

Cellular Biophysics, Roswell Park Gradu<strong>at</strong>e Division of the <strong>University</strong> <strong>at</strong> <strong>Buffalo</strong> and<br />

an Associ<strong>at</strong>e Professor in the <strong>University</strong>’s Department of Structural Biology.<br />

Research: Dr. Ghosh is interested in the structural endocrinology of estrogen synthesis<br />

and metabolism as well as breast cancer drug design. Currently, he is investig<strong>at</strong>ing<br />

three enzymes th<strong>at</strong> play a critical role in controlling the active level of estrogen in breast<br />

tissue, vital targets for anti-breast cancer drugs.<br />

Educ<strong>at</strong>ion: He received his B.S. in Physics, Chemistry, and M<strong>at</strong>hem<strong>at</strong>ics from St.<br />

Xavier’s College and earned his M.S. in Physics and his M.Sc. in Biophysics from the<br />

Indian <strong>Institute</strong> of Technology and the Saha <strong>Institute</strong> of Nuclear Physics, respectively.<br />

Upon leaving India, he completed his Ph.D. <strong>at</strong> the <strong>University</strong> of Pittsburgh in Crystallography<br />

and his post-doctoral work <strong>at</strong> Carnegie-Mellon <strong>University</strong>.<br />

Noteworthy Contributions: Dr. Ghosh is a Cancer Research Scientist and Associ<strong>at</strong>e<br />

Member <strong>at</strong> the Roswell Park Cancer <strong>Institute</strong>.<br />

David A. Langs, Ph.D.<br />

Position: Senior Research Scientist<br />

Appointments: He serves as an Associ<strong>at</strong>e Professor in the Department of Structural<br />

Biology.<br />

Research: Longtime interests include both the structure and function of ion channels<br />

and methods of crystal structure determin<strong>at</strong>ion. His specialty lies in solving structures<br />

others have previously found intractable. Currently he is developing methods for ab<br />

initio, and SIR and SAS phasing <strong>at</strong> low resolution.<br />

Educ<strong>at</strong>ion: Dr. Langs received his B.S. in Chemistry from St. Bonaventure <strong>University</strong><br />

and his Ph.D. in Inorganic Chemistry from the <strong>University</strong> <strong>at</strong> <strong>Buffalo</strong>.<br />

Noteworthy Contributions: He helped solve the crystal structure and mode of action<br />

of the antibiotic gramicidin A, and published the first detailed molecular-level model<br />

for the nifedipine binding site of the voltage-g<strong>at</strong>ed Calcium channel. His public<strong>at</strong>ions<br />

include more than 200 papers, chapters and abstracts.<br />

Vladimir Z. Pletnev, Ph.D.<br />

Position: Senior Research Scientist<br />

Appointments: Dr. Pletnev serves as Head of the X-ray Labor<strong>at</strong>ory <strong>at</strong> the Russian<br />

Academy of Sciences, <strong>Institute</strong> of Bioorganic Chemistry in Moscow.<br />

Research: Dr. Pletnev’s research interests include studying the three-dimensional organiz<strong>at</strong>ion,<br />

structure-function rel<strong>at</strong>ionship, and molecular mechanism of protein-peptide<br />

n<strong>at</strong>ure compounds using x-ray, molecular mechanics/dynamic/graphics, and bioinform<strong>at</strong>ics<br />

methods. Current proteins under examin<strong>at</strong>ion include short chain dehydrogenases,<br />

antibodies, and florescent proteins.<br />

Educ<strong>at</strong>ion: He received his M.S. in Chemistry from the Mendeleev <strong>Institute</strong> of Chemistry<br />

and Technology in Moscow and his Ph.D. in Bioorganic Chemistry and D.Sc. in<br />

Crystallography from the USSR Academy of Sciences in Moscow.<br />

Noteworthy Contributions: His public<strong>at</strong>ions include over 250 papers, chapters, and<br />

abstracts.<br />

Charles M. Weeks, Ph.D.<br />

Position: Senior Research Scientist<br />

Appointments: Dr. Weeks is a Professor in the Department of Structural Biology <strong>at</strong> the<br />

<strong>University</strong> <strong>at</strong> <strong>Buffalo</strong>.<br />

Research: His research includes the refinement of direct methods to determine the<br />

structure of macromolecules. He has developed the computer programs SnB and BnP<br />

th<strong>at</strong> implement the Shake-and-Bake method for solving molecular structures from<br />

crystallographic d<strong>at</strong>a.<br />

Educ<strong>at</strong>ion: Dr. Weeks received his B.S. in Biochemistry from Cornell <strong>University</strong> and his<br />

Ph.D. in Biophysics from the <strong>University</strong> <strong>at</strong> <strong>Buffalo</strong>.<br />

Noteworthy Contributions: Public<strong>at</strong>ions include over 280 papers, abstracts, and<br />

chapters. He has also been an invited lecturer <strong>at</strong> over 35 n<strong>at</strong>ional and intern<strong>at</strong>ional<br />

meetings and symposia.<br />

6 7


RESEARCH SCIENTISTS<br />

Barnali (Neel) Chaudhuri, Ph.D.<br />

Position: Research Scientist<br />

Appointments: She serves as an Assistant Professor in the Department of Structural<br />

Biology <strong>at</strong> the <strong>University</strong> <strong>at</strong> <strong>Buffalo</strong>.<br />

Research: Dr Chaudhuri's research is aimed <strong>at</strong> understanding the enzym<strong>at</strong>ic processing<br />

of the anticodon domains of the tRNAs. Given the central role of decoding events<br />

in cellular physiology, very little is understood about the enzym<strong>at</strong>ic targeting and<br />

processing of the tRNA anticodons. Therefore, Dr. Chaudhuri’s lab is studying the<br />

mechanism of these molecular recognition events. She also is interested in designing<br />

nano-sized molecular assemblies using protein modules as building blocks.<br />

Educ<strong>at</strong>ion: She received her Ph.D. in Molecular Biology from Uppsala <strong>University</strong> in Sweden.<br />

Andrew M. Gulick, Ph.D.<br />

Position: Research Scientist<br />

Appointments: He serves as an Assistant Professor in the Department of Structural<br />

Biology <strong>at</strong> the <strong>University</strong> <strong>at</strong> <strong>Buffalo</strong>.<br />

Research: Dr. Gulick uses X-ray crystallography to determine the molecular mechanisms<br />

th<strong>at</strong> enzymes use to c<strong>at</strong>alyze, or speed up, chemical reactions. His current research focuses<br />

on a family of large multi-domain enzymes th<strong>at</strong> synthesize peptides th<strong>at</strong> have antibiotic<br />

and anti-cancer activities. Members of this family also work with other proteins to make<br />

important molecules th<strong>at</strong> bacteria need to establish an infection in a susceptible host. An<br />

understanding of the structures and functions of these proteins will provide insights th<strong>at</strong><br />

may lead to the development of novel inhibitors th<strong>at</strong> could be used as anti-infective agents.<br />

Educ<strong>at</strong>ion: He received his B.S. in Biochemistry from Brown <strong>University</strong> and his Ph.D. in<br />

Experimental Oncology and Biochemistry from the <strong>University</strong> of Wisconsin-Madison.<br />

Noteworthy Contributions: Dr. Gulick has over twenty public<strong>at</strong>ions. He holds a<br />

p<strong>at</strong>ent on "Mutant Glut<strong>at</strong>hione S-Transferase Isoforms" th<strong>at</strong> were engineered to<br />

metabolize an anticancer drug.<br />

Peter J. Horn, Ph.D.<br />

Position: Research Scientist<br />

Appointments: He serves as an Assistant Professor for the Department of Structural<br />

Biology <strong>at</strong> the <strong>University</strong> <strong>at</strong> <strong>Buffalo</strong>.<br />

Research: His current work is centered on heterochrom<strong>at</strong>in organiz<strong>at</strong>ion and its regul<strong>at</strong>ion<br />

by a cullin-dependent ubiquitin ligase. This cullin family is widely conserved in<br />

many species, plays diverse nuclear roles, and is over-expressed or mis-regul<strong>at</strong>ed in<br />

some human cancers and genetic disorders. The current focus is on identifying its structural<br />

composition, wh<strong>at</strong> its substr<strong>at</strong>es might be, and how those substr<strong>at</strong>es are recognized<br />

by the enzyme. These studies will be critical to understanding how this enzyme<br />

particip<strong>at</strong>es in chromosome segreg<strong>at</strong>ion, DNA repair, and the progression of cancer.<br />

Educ<strong>at</strong>ion: Dr. Horn received a B.A. and M.S. in Biochemistry from Case Western<br />

Reserve <strong>University</strong> and his Ph.D. in Biochemistry from Michigan St<strong>at</strong>e <strong>University</strong>.<br />

Noteworthy Contributions: He was the first to show th<strong>at</strong> ubiquitinyl<strong>at</strong>ion regul<strong>at</strong>es<br />

heterochrom<strong>at</strong>in form<strong>at</strong>ion.<br />

Joseph R. Luft<br />

Position: Research Scientist<br />

Appointments: He serves as an Research Instructor in the Department of Structural<br />

Biology <strong>at</strong> the <strong>University</strong> <strong>at</strong> <strong>Buffalo</strong>.<br />

Research: His current work deals with development of new crystalliz<strong>at</strong>ion methods and<br />

techniques which include designing equipment for enhancing crystal growth capabilities<br />

and crystallizing proteins for use in various research projects.<br />

Educ<strong>at</strong>ion: He received his B.A. in Chemistry from D’Youville College.<br />

Noteworthy Contributions: He is co-inventor of two p<strong>at</strong>ented devices for growing<br />

crystals. The most recent high throughput robotics work has earned his group partnerships<br />

in two genomics consortium, Northeast Structural Genomics and Structural<br />

Genomics of P<strong>at</strong>hogenic Protozoa. He also leads the Crystal Growth effort within the<br />

Center for High Throughput Structural Biology.<br />

Michael G. Malkowski, Ph.D.<br />

Position: Research Scientist<br />

Appointments: He is an Assistant Professor in the Department of Structural Biology <strong>at</strong><br />

the <strong>University</strong> <strong>at</strong> <strong>Buffalo</strong>.<br />

Research: Dr. Malkowski's research interests focus on structure and functional studies<br />

of integral membrane proteins involved in lipid metabolism, f<strong>at</strong>ty acid des<strong>at</strong>ur<strong>at</strong>ion,<br />

and enzym<strong>at</strong>ic mechanisms of f<strong>at</strong>ty acid oxygen<strong>at</strong>ion. He serves as the project manager<br />

of the Center for High Throughput Structural Biology.<br />

Educ<strong>at</strong>ion: Dr. Malkowski received his B.Sc. and Ph.D. in Biochemistry from the<br />

<strong>University</strong> of Detroit and Wayne St<strong>at</strong>e <strong>University</strong>, respectively.<br />

L. Wayne Schultz, Ph.D.<br />

Position: Research Scientist<br />

Appointments: Dr. Schultz is an Assistant Professor in the Department of Structural<br />

Biology <strong>at</strong> the <strong>University</strong> <strong>at</strong> <strong>Buffalo</strong>.<br />

Research: He is currently investig<strong>at</strong>ing the SARS virus and coronavirus replic<strong>at</strong>ion and<br />

virus-host protein interactions, bioluminescence and cellular oxygen sensing.<br />

Educ<strong>at</strong>ion: Dr. Schultz received his B.A. in Chemistry from the College of Wooster and<br />

his M.S. and Ph.D., respectively in Analytical Chemistry and Biophysical Chemistry<br />

from Cornell <strong>University</strong>.<br />

Noteworthy Contributions: He holds a p<strong>at</strong>ent for “Engineered Cytotoxic Ribonuclease A.”


RESEARCH SCIENTISTS POST-DOCTORAL FELLOWS<br />

Edward H. Snell, Ph.D.<br />

Position: Research Scientist<br />

Appointments: Dr. Snell is an Assistant Professor in the Department of Structural<br />

Biology <strong>at</strong> the <strong>University</strong> <strong>at</strong> <strong>Buffalo</strong>.<br />

Research: Dr. Snell is developing experimental techniques to understand, control, and<br />

mitig<strong>at</strong>e the radi<strong>at</strong>ion damage th<strong>at</strong> occurs in X-ray crystallography studies of biological<br />

structures. Complementary to this, he is developing methods to enable a wider range of<br />

samples to be studied by neutron diffraction, a technique limited by crystal volume<br />

requirements. Ultim<strong>at</strong>ely the goal is to use a combin<strong>at</strong>ion of controlled radi<strong>at</strong>ion<br />

damage and neutron diffraction methods as techniques to resolve biological mechanisms<br />

especially where those mechanisms are redox or free-radical based.<br />

Educ<strong>at</strong>ion: Dr. Snell received his B.Sc. (Hons) in Applied Physics from John Moore<br />

<strong>University</strong> of Liverpool, UK, and his Ph.D. from the Chemistry Department of the<br />

<strong>University</strong> of Manchester, UK.<br />

Noteworthy Contributions: He holds a p<strong>at</strong>ent entitled “Method for Measurement of<br />

Physical Characteristics of Crystals.”<br />

Timothy C. Umland, Ph.D.<br />

Position: Research Scientist<br />

Appointments: He is an Assistant Professor in the Department of Structural Biology <strong>at</strong> the<br />

<strong>University</strong> <strong>at</strong> <strong>Buffalo</strong>.<br />

Research: A major interest of Dr. Umland is structural studies of the severe acute respir<strong>at</strong>ory<br />

syndrome (SARS) coronavirus, with an emphasis on viral proteins involved in replic<strong>at</strong>ion<br />

and host interactions. Other interests include determining the mechanism by<br />

which members of the Hox protein family act as “master regul<strong>at</strong>ors” of cellular differenti<strong>at</strong>ion<br />

and body segment<strong>at</strong>ion, particularly during embryonic development, and the 3�<br />

-hydroxysteriod dehydrogenase's role in steroid metabolism.<br />

Educ<strong>at</strong>ion: He received his B.S. in Chemistry from the <strong>University</strong> <strong>at</strong> <strong>Buffalo</strong> and his<br />

Ph.D. in Crystallography from the <strong>University</strong> of Pittsburgh.<br />

Noteworthy Contributions: He was an invited <strong>at</strong>tendee <strong>at</strong> the 2005 N<strong>at</strong>ional Academies<br />

Keck Futures Initi<strong>at</strong>ive Conference The Genomic Revolution: Implic<strong>at</strong>ions for the Tre<strong>at</strong>ment and<br />

Control of Infectious Disease. His research also provided the first structure of tetanus neurotoxin.<br />

Hongliang Xu, Ph.D.<br />

Position: Research Scientist<br />

Appointments: He serves as an Assistant Professor in the Department of Structural<br />

Biology <strong>at</strong> the <strong>University</strong> <strong>at</strong> <strong>Buffalo</strong>.<br />

Research: Research interests of Dr. Xu include direct methods of X-ray and neutron<br />

crystallographic phasing, comput<strong>at</strong>ional crystallography, and m<strong>at</strong>hem<strong>at</strong>ical biology.<br />

Educ<strong>at</strong>ion: Dr. Xu received both his B.S. and his M.S. in Comput<strong>at</strong>ional M<strong>at</strong>hem<strong>at</strong>ics<br />

from Peking <strong>University</strong>, and his M.S. in Industrial Engineering as well as his Ph.D. in<br />

M<strong>at</strong>hem<strong>at</strong>ics from the <strong>University</strong> <strong>at</strong> <strong>Buffalo</strong>.<br />

Noteworthy Contributions: His public<strong>at</strong>ions include more than 70 papers, abstracts,<br />

and chapters. Dr. Xu has been an invited lecturer <strong>at</strong> 12 n<strong>at</strong>ional and intern<strong>at</strong>ioal meetings<br />

and symposia.<br />

Shaun M. Bowman, Ph.D.<br />

Educ<strong>at</strong>ion: Ph.D. and M.S. in<br />

Biological Sciences from the<br />

<strong>University</strong> <strong>at</strong> <strong>Buffalo</strong>.<br />

Noteworthy Contributions:<br />

He has contributed to four<br />

public<strong>at</strong>ions.<br />

Qilong Mao, Ph.D.<br />

Educ<strong>at</strong>ion: Ph.D. in Molecular Biology and Biochemistry<br />

from the Tsinghua <strong>University</strong> in Beijing, China, M.S.<br />

in Biochemistry from the Nankai <strong>University</strong> in Tianjin,<br />

China and B.S. in Biology from the Beijing Normal<br />

<strong>University</strong> in Beijing, China.<br />

Noteworthy Contributions: He has published 11 papers.<br />

Mary Rosenblum, Ph.D.<br />

Educ<strong>at</strong>ion: Ph.D. in Chemistry from the <strong>University</strong> <strong>at</strong><br />

<strong>Buffalo</strong>, B.S. in Chemistry from Canisius College.<br />

Noteworthy Contributions: She has seven public<strong>at</strong>ions<br />

and has had an NIH postdoctoral fellowship <strong>at</strong> the<br />

<strong>University</strong> of Rochester working on Factor VIII with Dr.<br />

Phillip Fay for three years.<br />

Christopher C. Goulah, Ph.D.<br />

Educ<strong>at</strong>ion: Ph.D. in Microbiology<br />

and B.A. in Psychology<br />

from the <strong>University</strong> <strong>at</strong> <strong>Buffalo</strong>.<br />

Noteworthy Contributions:<br />

He has contributed to six<br />

public<strong>at</strong>ions.<br />

Nanette L. S. Que, Ph.D.<br />

Educ<strong>at</strong>ion: Ph.D. in Chemistry from the <strong>University</strong> of<br />

Minnesota, B.S. in Chemistry from the <strong>University</strong> of the<br />

Philippines.<br />

Noteworthy Contributions: She has published more<br />

than a dozen papers and currently has a p<strong>at</strong>ent pending.<br />

Manish Shah, Ph.D.<br />

Educ<strong>at</strong>ion: Ph.D. in Drug Discovery and Structural Biology,<br />

M.S. in Applied Biomolecular Technology as well as<br />

worked <strong>at</strong> AstraZeneca Pharmaceuticals, R&D - Alderley<br />

Park, Cheshire, England as a researcher during an industrial<br />

placement from <strong>University</strong> of Nottingham in England.<br />

B.S. in Pharmacy from Karn<strong>at</strong>ak <strong>University</strong> in India.<br />

Noteworthy Contributions: He has three public<strong>at</strong>ions.


RESEARCH ASSOCIATES<br />

Margaret Cegielski<br />

Position: Research Associ<strong>at</strong>e<br />

Educ<strong>at</strong>ion: B.S. in N<strong>at</strong>ural Sciences<br />

from Niagara <strong>University</strong><br />

Wendy A. Franke<br />

Position: Research Associ<strong>at</strong>e<br />

Educ<strong>at</strong>ion: A.A.S. in Medical<br />

Labor<strong>at</strong>ory Technology from Erie<br />

Community College<br />

Robin Kempkes<br />

Position: Research Associ<strong>at</strong>e<br />

Educ<strong>at</strong>ion: M.S. in Toxicology from<br />

the <strong>University</strong> of Nebraska Medical<br />

Center and a B.S. in Environmental<br />

Science from Canisius College<br />

Eric Drake<br />

Position: Research Associ<strong>at</strong>e<br />

Educ<strong>at</strong>ion: B.S. in Biology and Animal<br />

Science from Cornell <strong>University</strong><br />

James Fang<br />

Position: Research Associ<strong>at</strong>e<br />

Educ<strong>at</strong>ion: M.S. Peking Union Medical<br />

College, Beijing, P.R. China B.S.<br />

from Nankai, Univ., Tianjin, P.R. China<br />

Jessica Kocsis<br />

Position: Research Associ<strong>at</strong>e<br />

Educ<strong>at</strong>ion: B.S. in Biotechnology<br />

from the Rochester <strong>Institute</strong> of<br />

Technology<br />

Mary Erman<br />

Position: Sr. Research Associ<strong>at</strong>e<br />

Educ<strong>at</strong>ion: B.S. in Biology from<br />

D’Youville College<br />

Jennifer Griswold<br />

Position: Research Associ<strong>at</strong>e<br />

Educ<strong>at</strong>ion: B.S. in Biotechnology<br />

from the Rochester <strong>Institute</strong> of<br />

Technology<br />

Angela Lauricella<br />

Position: Research Associ<strong>at</strong>e<br />

Educ<strong>at</strong>ion: A.A.S. in Business<br />

Administr<strong>at</strong>ion from Erie Community<br />

College<br />

Tracy L. Lloyd<br />

Position: Sr. Research Associ<strong>at</strong>e<br />

Educ<strong>at</strong>ion: M.S. in Biochemistry, Washington<br />

St<strong>at</strong>e <strong>University</strong> and B.S. in Molecular<br />

Biology, Millersville St<strong>at</strong>e <strong>University</strong><br />

Jennifer Smith<br />

Position: Research Associ<strong>at</strong>e<br />

Educ<strong>at</strong>ion: B.S. in Biology from<br />

the St<strong>at</strong>e <strong>University</strong> of New York<br />

<strong>at</strong> Fredonia<br />

Jennifer Wolfley<br />

Position: Research Associ<strong>at</strong>e<br />

Educ<strong>at</strong>ion: B.A. in Chemistry and a<br />

B.S. in Criminalistics (Forensic Chemistry)<br />

from <strong>Buffalo</strong> St<strong>at</strong>e College<br />

James Pace<br />

Position: Research Associ<strong>at</strong>e<br />

Educ<strong>at</strong>ion: B.S. in Biology from<br />

the <strong>University</strong> of Miami<br />

Mary Elizabeth Snell<br />

Position: Research Associ<strong>at</strong>e<br />

Educ<strong>at</strong>ion: B.S. in Chemistry and a<br />

pending M.S. in Biology from<br />

<strong>University</strong> of Alabama <strong>at</strong> Huntsville<br />

Meriem Said<br />

Position: Research Associ<strong>at</strong>e<br />

Educ<strong>at</strong>ion: B.A. in Biophysics from<br />

John Hopkins <strong>University</strong><br />

Tina Ve<strong>at</strong>ch<br />

Position: Research Associ<strong>at</strong>e<br />

Educ<strong>at</strong>ion: B.S. in Educ<strong>at</strong>ion with a<br />

concentr<strong>at</strong>ion in N<strong>at</strong>ural Sciences<br />

and Biology from the St<strong>at</strong>e <strong>University</strong><br />

of New York <strong>at</strong> Geneseo


GRADUATE STUDENTS<br />

William Bauer<br />

Position: Gradu<strong>at</strong>e Student<br />

Educ<strong>at</strong>ion: B.A. in Molecular<br />

Biology from Elmira College<br />

David Parish<br />

Position: Gradu<strong>at</strong>e Student<br />

Educ<strong>at</strong>ion: M.S. in Electrical Engineering<br />

from Stanford <strong>University</strong>, B.S. in<br />

Electrical Engineering, B.A. in M<strong>at</strong>hem<strong>at</strong>ics<br />

from the <strong>University</strong> of Washington<br />

Jesse Sundlov<br />

Position: Gradu<strong>at</strong>e Student<br />

Educ<strong>at</strong>ion: B.S. in Biology from<br />

Johns Hopkins <strong>University</strong><br />

Robert Huether<br />

Position: Gradu<strong>at</strong>e Student<br />

Educ<strong>at</strong>ion: M.A. and B.S. in Biological<br />

Science from the <strong>University</strong> <strong>at</strong> <strong>Buffalo</strong><br />

Albert Reger<br />

Position: Gradu<strong>at</strong>e Student<br />

Educ<strong>at</strong>ion: B.S. in Biology from<br />

Niagara <strong>University</strong><br />

Alex Vecchio<br />

Position: Gradu<strong>at</strong>e Student<br />

Educ<strong>at</strong>ion: B.S. in Biology from<br />

Rochester <strong>Institute</strong> of Technology<br />

Zachary Miknis<br />

Position: Gradu<strong>at</strong>e Student<br />

Educ<strong>at</strong>ion: B.S. in Biology and<br />

B.A. in Philosophy from the<br />

<strong>University</strong> of Scranton<br />

Danielle Simmons<br />

Position: Gradu<strong>at</strong>e Student<br />

Educ<strong>at</strong>ion: B.S. in Biology from<br />

St. Bonaventure <strong>University</strong><br />

Sanjay Connare<br />

Position: Research Aide<br />

Educ<strong>at</strong>ion: Working to complete<br />

a dual bachelor’s degree in<br />

economics and computer science<br />

<strong>at</strong> the <strong>University</strong> <strong>at</strong> <strong>Buffalo</strong><br />

Ann M. Wojtaszczyk<br />

Position: Student Intern<br />

Educ<strong>at</strong>ion: Currently a student <strong>at</strong><br />

Canisius College where she is<br />

studying biochemistry<br />

Lynn Nyazika<br />

Position: Research Aide<br />

Educ<strong>at</strong>ion: Studying pre-medicine<br />

and Chemistry, with a minor in<br />

Inform<strong>at</strong>ion Technology <strong>at</strong> D’Youville<br />

College<br />

Jimmitti Teysir<br />

Position: Student Intern<br />

Educ<strong>at</strong>ion: Currently a student <strong>at</strong><br />

City Honors High School<br />

RESEARCH AIDES AND INTERNS<br />

Amy L. DeLuca<br />

Position: Student Intern<br />

Educ<strong>at</strong>ion: Currently a student <strong>at</strong><br />

Canisius College where she is<br />

studying chemistry


ADMINISTRATION COMPUTER SYSTEMS DEVELOPMENT FINANCIAL MANAGEMENT GRAPHIC DESIGN PUBLIC RELATIONS AND GOVERNMENT AFFAIRS<br />

Jean Gallmeyer<br />

Position: Senior Administr<strong>at</strong>ive<br />

Assistant<br />

Darlene Miller<br />

Position: Facilities Aide<br />

Raymond M. Nagel<br />

Position: Software Developer<br />

Educ<strong>at</strong>ion: B.S. in Computer<br />

Inform<strong>at</strong>ion Systems from <strong>Buffalo</strong><br />

St<strong>at</strong>e College<br />

Dorothy Grimes<br />

Position: Administr<strong>at</strong>ive Assistant<br />

Educ<strong>at</strong>ion: A.O.S. in Administr<strong>at</strong>ive &<br />

Legal Assistance from Bryant and Str<strong>at</strong>ton<br />

Daniel P. Degnan<br />

Position: Director of Inform<strong>at</strong>ion Technology<br />

Educ<strong>at</strong>ion: B.S. in Medical Technology<br />

from the <strong>University</strong> <strong>at</strong> <strong>Buffalo</strong>. He is also<br />

certified as an MCSE, MCP, A+ and is a<br />

Licensed Clinical Labor<strong>at</strong>ory Technologist<br />

Stephen A. Potter<br />

Position: Computer Systems Manager<br />

Educ<strong>at</strong>ion: B.S. in Physics from the<br />

<strong>University</strong> <strong>at</strong> <strong>Buffalo</strong><br />

Deanna Hefner<br />

Position: Human Resource Manager<br />

Educ<strong>at</strong>ion: A.A.S. in Medical Office<br />

Assistant from Erie Community<br />

College<br />

Geoffrey Franks<br />

Position: Systems Administr<strong>at</strong>or<br />

Educ<strong>at</strong>ion: B.S. in Applied Networking<br />

and Systems Administr<strong>at</strong>ion from<br />

the Rochester <strong>Institute</strong> of Technology<br />

Max Thayer<br />

Position: Software Developer<br />

Educ<strong>at</strong>ion: B.S. in Computer Inform<strong>at</strong>ion<br />

Systems from <strong>Buffalo</strong> St<strong>at</strong>e<br />

College, A.S. in Applied Science<br />

in Computer Systems from Alfred<br />

St<strong>at</strong>e College of Technology<br />

Laurie Elliott Krajna<br />

Position: Capital Campaign Manager<br />

Educ<strong>at</strong>ion: B.S. in Business Economics<br />

from College of Wooster<br />

Anne Kent<br />

Position: Controller<br />

Educ<strong>at</strong>ion: B.S. in Finance from<br />

<strong>Buffalo</strong> St<strong>at</strong>e College<br />

Gloria J. Del Bel<br />

Position: Principal Graphic Designer<br />

Educ<strong>at</strong>ion: B.F.A. in Printmaking<br />

from <strong>Buffalo</strong> St<strong>at</strong>e College and an<br />

A.A.S. in Graphic Design from<br />

Villa Maria College<br />

Lisa Foti Milk, CPA<br />

Position: Chief Financial Officer<br />

Educ<strong>at</strong>ion: B.S./B.A. in Accounting<br />

and Finance from the <strong>University</strong><br />

<strong>at</strong> <strong>Buffalo</strong><br />

Michael Logar<br />

Position: Assistant Controller<br />

Educ<strong>at</strong>ion: B.S. in Business Administr<strong>at</strong>ion,<br />

Accounting from <strong>Buffalo</strong> St<strong>at</strong>e<br />

College, A.A.S. in Business Administr<strong>at</strong>ion<br />

from Niagara County Community<br />

College<br />

Melda Tugac<br />

Position: Department Head,<br />

Graphic Design<br />

Educ<strong>at</strong>ion: B.A. in Liberal Arts<br />

from <strong>University</strong> of Istanbul, Turkey<br />

Michael Gurrea<br />

Position: Staff Accountant<br />

Educ<strong>at</strong>ion: Attending <strong>Buffalo</strong> St<strong>at</strong>e<br />

College for Business Administr<strong>at</strong>ion<br />

Melissa Couchman<br />

Position: Support Associ<strong>at</strong>e<br />

Educ<strong>at</strong>ion: B.S. in Business Administr<strong>at</strong>ion<br />

from Daemen College and<br />

an A.A.S. in Business Administr<strong>at</strong>ion<br />

from Erie Community College<br />

Tara A. Ellis<br />

Position: Director of Public Rel<strong>at</strong>ions<br />

Educ<strong>at</strong>ion: M.S. in Public Communic<strong>at</strong>ions<br />

from the S.I. Newhouse<br />

School <strong>at</strong> Syracuse <strong>University</strong>, B.A.<br />

in English Liter<strong>at</strong>ure from the<br />

<strong>University</strong> <strong>at</strong> <strong>Buffalo</strong>


CAPITAL CAMPAIGN DONORS DONOR HIGHLIGHTS<br />

In 2002, <strong>Hauptman</strong>-<strong>Woodward</strong>’s Board of Directors and Leadership Team recognized the<br />

need to modernize its facilities. The building <strong>at</strong> 73 High Street was no longer able to house<br />

the increasingly technologically advanced labs and equipment th<strong>at</strong> HWI needed to compete<br />

n<strong>at</strong>ionally and intern<strong>at</strong>ionally for scientific recruits and financial grants.<br />

A decision was made to build a new st<strong>at</strong>e-of-the-art biomedical research facility.<br />

The generosity of the donors listed below has made th<strong>at</strong> dream a reality. We would like to<br />

thank the following donors for supporting the capital campaign, The Cures Begin Here, <strong>at</strong><br />

<strong>Hauptman</strong>-<strong>Woodward</strong>:<br />

$14,000,000<br />

Empire St<strong>at</strong>e Development Corpor<strong>at</strong>ion<br />

$3,500,000<br />

John R. Oishei Found<strong>at</strong>ion<br />

$1,500,000<br />

The Margaret L. Wendt Found<strong>at</strong>ion<br />

$500,000 - $1,499,999<br />

James H. Cummings Found<strong>at</strong>ion, Inc.<br />

Constance W. Stafford Charitable Trust<br />

$200,000 - $499,999<br />

The Baird Found<strong>at</strong>ion<br />

Mr. William J. Constantine<br />

Grigg-Lewis Found<strong>at</strong>ion<br />

Richard W. and Mae Stone Goode Trust<br />

Mr. & Mrs. Paul J. Koessler<br />

$100,000 - $199,999<br />

Mr. & Mrs. Clement R. Arrison<br />

Cameron Baird Found<strong>at</strong>ion<br />

Community Found<strong>at</strong>ion for<br />

Gre<strong>at</strong>er <strong>Buffalo</strong><br />

Mr. & Mrs. Walter J. Constantine, Jr.<br />

The Children’s Guild<br />

Mrs. Whitworth Ferguson, Jr.,<br />

Ferguson Family Found<strong>at</strong>ion, Inc.,<br />

Ferguson Electric Found<strong>at</strong>ion<br />

Mr. & Mrs. Peter B. Flickinger,<br />

Mr. & Mrs. Thomas R. Flickinger,<br />

Mr. William S. Flickinger<br />

Mr. & Mrs. Donald Hess<br />

Pamela Jacobs Vogt and family<br />

Seymour H. Knox Found<strong>at</strong>ion<br />

M&T Charitable Found<strong>at</strong>ion<br />

William McGowan Charitable Trust<br />

Dr. & Mrs. Walter F. Stafford, III<br />

$50,000 - $99,999<br />

Mr. & Mrs. Charles E. Balbach<br />

Edward H. Butler Found<strong>at</strong>ion<br />

Peter Cornell Trust<br />

Adele and George DeTitta<br />

Jaeckle, Fleischmann & Mugel, LLP<br />

Moog, Inc.<br />

Phyllis W. Pierce Charitable Lead<br />

Annuity Trust<br />

Lawrence Quinn<br />

Mr. & Mrs. Robert Wilmers<br />

$20,000 - $49,999<br />

Mrs. Marjorie Buyers<br />

Mr. & Mrs. Frank Ciminelli<br />

Mr. John Cordes &<br />

Ms. Michele Heffernan<br />

Dr. and Mrs. Angelo M. F<strong>at</strong>ta<br />

First Niagara Bank Found<strong>at</strong>ion<br />

Freed, Maxick & B<strong>at</strong>taglia CPA’s PC<br />

Jane and Richard Griffin<br />

Mr. & Mrs. Thomas R. Hyde<br />

Mr. & Mrs. John A. Mitchell<br />

Verizon Found<strong>at</strong>ion<br />

Western New York Found<strong>at</strong>ion<br />

Mr. & Mrs. Gilbert Yager<br />

$10,000 - $19,999<br />

Dr. & Mrs. Richard A. Aubrecht<br />

Citizens Bank<br />

John W. Danforth Company<br />

Mr. & Mrs. Charles Dowdell<br />

Dr. Edith Flanigen<br />

Mr. & Mrs. Christopher T. Greene<br />

Josephine Goodyear Found<strong>at</strong>ion<br />

Sarah Goodyear<br />

Mr. & Mrs. Wilson Gre<strong>at</strong>b<strong>at</strong>ch<br />

Dr. & Mrs. David Hohn<br />

Dr. & Mrs. L. Nelson Hopkins, III<br />

Mrs. N. Jane Maroone<br />

The Pearce Family<br />

Rotary Found<strong>at</strong>ion of <strong>Buffalo</strong><br />

Mr. & Mrs. Douglas G. Swift<br />

Mr. & Mrs. John M. Wadsworth<br />

$5,000 - $9,999<br />

Mr. & Mrs. Henry H. Baxter<br />

Mr. & Mrs. Thomas R. Beecher, Jr.<br />

Mr. & Mrs. Norbert A. Bennett<br />

Mr. & Mrs. James R. Biltekoff<br />

Mr. & Mrs. Jerry Castiglia<br />

Frances G. Churchill Fund<br />

Walsh Duffield Companies, Inc.<br />

Mr. Finley R. Greene, Jr.<br />

Mr. & Mrs. Donald J. Holzman<br />

Mr. William N. Hudson, Jr.<br />

Mr. & Mrs. Theodore E. Marks<br />

McGard, Inc.<br />

Dr. & Mrs. Peter Ostrow<br />

Dr. & Mrs. Walter Pangborn<br />

Mr. & Mrs. Theodore Rich<br />

Mr. & Mrs. Robert E. Sadler, Jr.<br />

Mr. Richard Shaughnessy<br />

Mr. & Mrs. Brian Townson<br />

VIYU Found<strong>at</strong>ion<br />

$1,000 - $4,999<br />

Mrs. C. Angela Bontempo<br />

Dr. Vivian Cody<br />

Mr. & Mrs. Richard W. Cutting<br />

Mrs. Erika Daley<br />

Mr. & Mrs. James Degen<br />

DeSpirt Mosaic & Marble Co., Inc<br />

Donald Davis Found<strong>at</strong>ion<br />

Mr. & Mrs. Fred Friedman<br />

Mr. & Mrs. Richard E. Garman<br />

Dr. & Mrs. Herbert A. <strong>Hauptman</strong><br />

Invitrogen Corpor<strong>at</strong>ion<br />

Kaleida Health<br />

Mr. & Mrs. Bernard J. Kennedy<br />

Mrs. Mary M. Koessler<br />

Mr. & Mrs. Anthony B. Martino<br />

The Messer Found<strong>at</strong>ion<br />

Mrs. Lisa Foti Milk<br />

Mr. Kenneth F. Myszka<br />

Dr. & Mrs. Yoshio Osawa<br />

Mr. & Mrs. William J. Regan, Jr.<br />

Mr. & Mrs. Emmett L. Reilly<br />

Mr. & Mrs. Kevin G. Reilly<br />

Mr. & Mrs. P<strong>at</strong>rick Reilly<br />

Mrs. Lois F. Renz<br />

Sevenson Environmental Services<br />

Mrs. Constance S. Umland<br />

Mr. Richard R. Upton<br />

LIFE MEMBERS<br />

Mrs. Gilbert J. Yager<br />

We would like to thank and acknowledge the following donors to <strong>Hauptman</strong>-<strong>Woodward</strong>,<br />

making a gift in our fiscal year <strong>2006</strong>. (November 1, 2005 – October 31, <strong>2006</strong>)<br />

$250,000+<br />

The Est<strong>at</strong>e of Jackson C<strong>at</strong>t<br />

James H. Cummings Found<strong>at</strong>ion<br />

$100,000<br />

The Grigg-Lewis Found<strong>at</strong>ion<br />

$50,000 - $99,999<br />

Mr. & Mrs. Clement R. Arrison<br />

Arthritis Found<strong>at</strong>ion<br />

The Baird Found<strong>at</strong>ion<br />

The Cameron Baird Found<strong>at</strong>ion<br />

The Children’s Guild<br />

Mr. William J. Constantine<br />

Richard & Mae Stone Goode Trust<br />

The family of Dr. Lawrence Jacobs<br />

Key Found<strong>at</strong>ion<br />

Seymour H. Knox Found<strong>at</strong>ion<br />

Constance W. Stafford Charitable Trust<br />

Margaret L. Wendt Found<strong>at</strong>ion<br />

Mr. & Mrs. Robert Wilmers<br />

$25,000 - $49,999<br />

<strong>Buffalo</strong> Medical Group<br />

Mr. & Mrs. Thomas R. Hyde<br />

Mr. & Mrs. Paul J. Koessler<br />

M&T Charitable Found<strong>at</strong>ion<br />

$10,000 - $24,999<br />

Mr. & Mrs. Charles E. Balbach<br />

Edward H. Butler Found<strong>at</strong>ion<br />

Mr. John Cordes & Ms. Michele Heffernan<br />

The Community Found<strong>at</strong>ion for Gre<strong>at</strong>er <strong>Buffalo</strong><br />

Mr. & Mrs. Donald Hess<br />

Josephine Goodyear Found<strong>at</strong>ion<br />

Kaleida Health<br />

Moog, Inc.<br />

Mrs. N. Jane Maroone<br />

Mrs. Joseph Stewart<br />

Verizon Found<strong>at</strong>ion<br />

PARTNER’S IN RESEARCH<br />

$5,000 - $9,999<br />

Dr. and Mrs. Richard A. Aubrecht<br />

Mr. & Mrs. Jerry Castiglia<br />

Citizens Bank<br />

Mr. and Mrs. Walter Constantine, Jr.<br />

Adele and George DeTitta<br />

Dr. and Mrs. Angelo M. F<strong>at</strong>ta<br />

Mrs. Whitworth Ferguson, Jr.<br />

Ferguson Electric Found<strong>at</strong>ion<br />

Ferguson Family Found<strong>at</strong>ion, Inc.<br />

Ms. Edith M. Flanigen<br />

Frances G. Churchill Fund<br />

Jane and Richard Griffin<br />

Key Bank<br />

Mr. and Mrs. Vincent Lawless<br />

Little-Kittinger Found<strong>at</strong>ion<br />

Louis S. & Molly B. Wolk Found<strong>at</strong>ion<br />

McDonald Financial Group<br />

Mr. and Mrs. John A. Mitchell<br />

NYS Center of Excellence<br />

Praxair, Inc.<br />

Research Found<strong>at</strong>ion of SUNY<br />

Mr. and Mrs. Theodore Rich<br />

Scott, Danahy & Naylon Co., Inc.<br />

Dr. and Mrs. Walter F. Stafford, III<br />

Mr. and Mrs. Douglas G. Swift<br />

United Way of <strong>Buffalo</strong> & Erie County<br />

VIYU Found<strong>at</strong>ion<br />

DIAMOND CIRCLE MEMBERS<br />

$2,500 - $4,999<br />

Mr. and Mrs. Norbert A. Bennett<br />

Mrs. Marjorie Buyers<br />

Mr. and Mrs. Christopher T. Greene<br />

Dr. and Mrs. David C. Hohn<br />

Jaeckle, Fleischmann & Mugel, LLP<br />

John W. Danforth Company Found<strong>at</strong>ion, Inc.<br />

Mr. & Mrs. Bernard J. Kennedy<br />

Mr. and Mrs. G. David Koepf<br />

Lifetime Health<br />

Mr. and Mrs. Robert L. Montgomery, Jr.<br />

Dr. and Mrs. Walter A. Pangborn<br />

Roswell Park Cancer <strong>Institute</strong><br />

U&S Services<br />

Walsh Duffield Companies, Inc.<br />

CRYSTAL CIRCLE MEMBERS<br />

$1,500 - $2,499<br />

Berger & Berger<br />

Mr. and Mrs. James R. Biltekoff<br />

Bristol-Myers Squibb Found<strong>at</strong>ion, Inc.<br />

<strong>Buffalo</strong> Museum of Science<br />

<strong>Buffalo</strong> Niagara Medical Campus<br />

Mr. and Mrs. Gary M. Burger<br />

Mr. and Mrs. Bruce Buyers<br />

Computer Task Group, Inc.<br />

Damon & Morey LLP<br />

Mrs. Cynthia Doolittle<br />

Dr. and Mrs. William L. Duax<br />

Mr. and Mrs. Thomas R. Flickinger<br />

Freed, Maxick & B<strong>at</strong>taglia CPA's PC<br />

Mr. and Mrs. Richard E. Garman<br />

Irenaeus Found<strong>at</strong>ion<br />

Key Bank<br />

Dr. and Mrs. Yoshio Osawa<br />

Pearce Family<br />

Peter & Elizabeth C. Tower Found<strong>at</strong>ion<br />

Savarino Companies<br />

Sevenson Environmental Services<br />

SUNY Health Sciences<br />

UB STOR<br />

CIRCLE PATRONS<br />

$1,000 - $1,499<br />

Mr. and Mrs. Thomas R. Beecher, Jr.<br />

Mr. and Mrs. Maxwell Caulkins<br />

Mr. and Mrs. Richard W. Cutting<br />

Mr. and Mrs. James Degen<br />

Mr. and Mrs. Thomas C. Detwiler<br />

Mrs. Jeanne C. E<strong>at</strong>on<br />

Ellicott Development Company<br />

Mrs. Marion Flemming<br />

Mr. and Mrs. Fred Friedman<br />

Mrs. Anne L. Gardner<br />

Mr. and Mrs. Robert J. A. Irwin<br />

Ms. Lucetta C. Knox<br />

Mrs. Mary M. Koessler<br />

Dr. K<strong>at</strong>hleen Kreis<br />

Mr. Norman E. Mack, II<br />

Mr. and Mrs. Jeffrey B. Marsh<br />

Mr. and Mrs. Anthony B. Martino<br />

Mr. and Mrs. E. Dennis McCarthy<br />

Mr. & Mrs. Lewis McCauley<br />

Mr. and Mrs. Donald M. McClellan<br />

Mrs. Lisa Foti Milk<br />

Mills Welding Supply<br />

Mr. and Mrs. William J. Regan, Jr.<br />

Research Facilities Design<br />

Rigaku-MSC<br />

Rigidized Metals<br />

Mr. Richard W. Shaughnessy<br />

Souter Productions Inc<br />

Mr. and Mrs. Reid W. Stafford<br />

Mrs. Richard W. Stewart<br />

The <strong>Buffalo</strong> News<br />

UBS Found<strong>at</strong>ion USA M<strong>at</strong>ching Gift Program<br />

Mr. Richard R. Upton<br />

Mr. and Mrs. Samuel F. Ward<br />

CIRCLE SPONSORS<br />

$500- $999<br />

Mr. and Mrs. Charles Lee Abell<br />

Mr. and Mrs. Douglas T. Baker<br />

Mr. and Mrs. Henry H. Baxter, P.E.<br />

Dr. and Mrs. Theodore S. Bistany<br />

Mr. and Mrs. Michael A. Brady<br />

Mr. and Mrs. Theodore Chertoff<br />

DeSpirt Mosaic & Marble Co., Inc.<br />

Mr. and Mrs. Alan L. Dressler<br />

Dr. Edward G. Eberl<br />

Dr. Eugene L. Gaier<br />

Dr. Robert J. Genco<br />

Mr. and Mrs. Christopher Gibas<br />

Mr. Thomas More Griffin<br />

Dr. Kenneth W. Gross<br />

Mr. Charles J. Hahn<br />

Dr. Barbara Henderson<br />

Mr. and Mrs. Chris Henderson<br />

Dr. and Mrs. L. Nelson Hopkins, III<br />

Mr. John T. Hoskins<br />

HSBC M<strong>at</strong>ching Gift Program<br />

Mr. and Mrs. Hartley Frank Hutchins<br />

Johnson & Johnson<br />

Mr. and Mrs. William L. Joyce<br />

Drs. James R. Kanski<br />

Honorable and Mrs. Theodore S. Kasler<br />

Mr. and Mrs. Charles F. Kreiner, Sr.<br />

Drs. Susan Graham & Jon C. Kucera<br />

Dr. and Mrs. Paul Kurtz<br />

Mr. and Mrs. Anthony M Masiello<br />

Dr. and Mrs. J. Arthur M<strong>at</strong>tern<br />

Mr. and Mrs. Richard Minekime<br />

Dr. and Mrs. Herman S. Mogavero, Jr.<br />

Niagara Aerospace Museum<br />

Dr. and Mrs. Peter T. Ostrow<br />

Miss Frances M. Rew<br />

Mr. and Mrs. Edward B. Righter<br />

Rotary Club of <strong>Buffalo</strong><br />

Mr. and Mrs. John G Stanley, Jr.<br />

The Floristry


DONOR HIGHLIGHTS<br />

CIRCLE SPONSORS<br />

$500 - $999<br />

Mr. and Mrs. James M. Wadsworth<br />

Mr. William Wadsworth<br />

Mr. Arthur J. Ziffer<br />

Mr. and Mrs. C. Richard Zobel<br />

CIRCLE MEMBERS<br />

$250 - $499<br />

Accumed Technologies Inc.<br />

Mr. and Mrs. C. Teo Balbach<br />

Mrs. Wavel H. Barber<br />

Mrs. Janice C. Boneberg<br />

BuffLink, Inc.<br />

Mr. and Mrs. Robert M. Butcher<br />

Dr. and Mrs. T. Ming Chu<br />

Dr. Vivian Cody<br />

Mrs. William J. Conners, III<br />

Mr. and Mrs. John R. Connolly<br />

Mr. and Mrs. Arthur W. Cryer<br />

Mr. and Mrs. Thomas H. Danforth<br />

Mr. and Mrs. Michael Day<br />

Dr. and Mrs. Peter C. Dow<br />

Ms. Jennifer Dowdell<br />

Dr. and Mrs. Edmund Egan<br />

Mr. and Mrs. Stephen R. Foley<br />

Garrett Le<strong>at</strong>her Corpor<strong>at</strong>ion<br />

Mr. Finley R. Greene, Jr.<br />

Dr. and Mrs. Bruce <strong>Hauptman</strong><br />

Mrs. Ann Holland Cohn<br />

Mrs. L. Nelson Hopkins, Jr.<br />

HP Employee Charitable Giving Program<br />

Mr. and Mrs. William Baird Irwin<br />

Dr. and Mrs. Herbert E. Joyce<br />

Dr. and Mrs. Kenneth R. Kahn<br />

Dr. Chari Briggs & Mr. Joel Krenis<br />

Mr. and Mrs. Robert J. Kresse<br />

Louis P. Ciminelli Construction Co., Inc.<br />

Marks Family Found<strong>at</strong>ion<br />

Mrs. Walter J. M<strong>at</strong>t<br />

Mr. and Mrs. Arnold Maxick<br />

Mr. and Mrs. Richard E. McGill<br />

Mr. and Mrs. Clarke H. Narins<br />

Mr. and Mrs. Reginald B. Newman, II<br />

Drs. Dean & Donna Orman<br />

Ms. Michelle Pangborn<br />

Dr. and Mrs. John H. Peterson<br />

Mr. Richard S. Piccoli<br />

Ms. Wendy Pierce<br />

Mrs. Marjorie M. Plumb<br />

Mr. and Mrs. P<strong>at</strong>rick Reilly<br />

Dr. and Mrs. Peter Schaber<br />

Mr. and Mrs. C. Jacob Schneider<br />

Mr. and Mrs. James R. Spengler, Jr.<br />

The Premier Group Member Wine Stores<br />

Dr. and Mrs. James F. Upson<br />

Mr. and Mrs. Hugh M. Van Alstyne<br />

Mrs. Nancy S. Warner<br />

W<strong>at</strong>son, Bennett, Colligan, Johnson &<br />

Schechter LLP<br />

Mr. and Mrs. Wayne D. Wisbaum<br />

WomenStories<br />

SUPPORTERS<br />

$100 - $249<br />

Dr. and Mrs. Mark W. Ackley<br />

Mr. and Mrs. Robert J. Adams<br />

Mr. and Mrs. J. Keith Alford<br />

Ms. Anne Allan<br />

Mr. and Mrs. Stephen C. Ames<br />

Mr. and Mrs. Gordon P. Assad<br />

Mr. Herbert A. Aurbach<br />

Mr. and Mrs. Virgil J. Austin<br />

Dr. and Mrs. Allen Barnett<br />

Mr. and Mrs. Rudolf L. Bauer<br />

Dr. and Mrs. Robert A. Baumler<br />

Ms. Ellen W. Baxter<br />

Mrs. Sharon R. Bouvier<br />

Mr. Brian P. Brady<br />

Mr. and Mrs. Thomas H. Brown<br />

Ms. Audre Bunis<br />

Ms. Martha Burke<br />

Mr. Leroy G. Callahan<br />

Dr. and Mrs. Chun-Shi Chang<br />

Dr. and Mrs. Norman Chassin<br />

Dr. and Mrs. David E. Chesebrough<br />

Ms. Ann W. Christiansen<br />

Dr. and Mrs. Abraham Clearfield<br />

Miss Mary E. Clemesha<br />

Mr. Donald H. Cloudsley<br />

Mrs. Margaret R. Cole<br />

Mrs. Nancy M. Conley<br />

Dr. and Mrs. Donald P. Copley<br />

Mr. and Mrs. John Courtin<br />

Mr. and Mrs. Robert B. Cozzens<br />

Mr. and Mrs. James L. Crane, Jr.<br />

Mrs. Robert C. Cummings<br />

Mr. and Mrs. Anthony D. Decillis<br />

Mr. and Mrs. Michael Degen<br />

Mr. John Dicky<br />

Mr. and Mrs. J. P<strong>at</strong>rick Donlon<br />

Mr. and Mrs. Kenneth Drake<br />

John Dyster<br />

Mr. Wyndham E<strong>at</strong>on<br />

Mr. and Mrs. Frank Eberl<br />

Mr. and Mrs. Adelbert Fleischmann<br />

Mr. and Mrs. Marvin Frankel<br />

Mr. and Mrs. Richard L. Freeman<br />

Mr. Richard L. Friend<br />

Mrs. Carolyn F. Gallivan<br />

Mrs. Jean Gallmeyer<br />

Ms. Lillian Gerstman<br />

Dr. and Mrs. A. Donald Gilden<br />

Mr. and Mrs. Irwin E. Ginsberg<br />

Mrs. Alvin Glick<br />

Dr. James E. Glogowski<br />

Dr. Lee Ann Grace<br />

Dr. and Mrs. Gary Grosner<br />

Mr. Robert W. Gundlach<br />

Mrs. Herman Haber<br />

Mr. and Mrs. Halem J. Habib<br />

Mr. and Mrs. Calvin J. Haller<br />

Mary, Elizabeth, & David Handley<br />

Dr. David G. Hangauer<br />

Miss Deanna Hefner<br />

Mr. and Mrs. Sherlock A. Herrick, Jr.<br />

Mr. and Mrs. Myron M. Hunt<br />

HWI Staff<br />

Mrs. Mary L. Hyde<br />

Mr. and Mrs. Clinton F. Ivins, Jr.<br />

Mr. and Mrs. Robert Johnson<br />

Mr. Edwin M. Johnston, Jr.<br />

Mr. and Mrs. John L. Kirschner<br />

Mrs. Betty D. Kittinger<br />

Mr. John J. Klosterman<br />

Dr. and Mrs. Todd B. Koch<br />

Mr. and Mrs. Herbert P. Ladds, Jr.<br />

Mr. and Mrs. Timothy P. Lafferty<br />

Mr. and Mrs. Sheldon T. Lenahan<br />

Dr. and Mrs. Jack Lippes<br />

Mr. John C. Lundrigan<br />

Mr. and Mrs. Gary Maas<br />

Mader Construction Co., Inc.<br />

Mr. and Mrs. John Maley<br />

Dr. and Mrs. Edward J. Marine<br />

Mr. and Mrs. Theodore E. Marks, III<br />

Mr. and Mrs. Robert J. Martin<br />

Ms. Regina Mastroleo<br />

Ms. Eileen R. McCallister<br />

Dr. Mary McCourt<br />

Mr. Gilbert G. McCurdy<br />

Mr. and Mrs. Kevin McDermott<br />

Militello's Luggage<br />

Mrs. Darlene Miller<br />

Mr. and Mrs. Glen Miller<br />

Millington Lockwood, Inc.<br />

Mr. and Mrs. John Mineo<br />

Dr. Edwin A. Mirand<br />

Mr. Edwin Munschauer, Jr.<br />

Dr. and Mrs. Richard B. Narins<br />

N<strong>at</strong>ional Fuel Gas Company Found<strong>at</strong>ion<br />

Nixon Peabody LLP<br />

Dr. James Notaro<br />

Ms. Greta Pangborn<br />

Mr. Kenneth R. Paslaqua<br />

Mr. and Mrs. Charles E. Paul<br />

Ms. Alice Peek<br />

Mr. and Mrs. George F. Phillips, Jr.<br />

Dr. and Mrs. James F. Phillips<br />

Mr. and Mrs. Michael A. Piette<br />

Mr. and Mrs. H. William Pollack, II<br />

Mr. William Potter<br />

Dr. and Mrs. Theodore C. Prentice<br />

Mr. and Mrs. Ted Pyrak<br />

Mr. and Mrs. David S. Quackenbush<br />

Quaker Bonnet E<strong>at</strong>ery<br />

Ms. Elizabeth D. Reidp<strong>at</strong>h<br />

Mr. and Mrs. Wayne R. Reilly<br />

Mr. and Mrs. George E. Riedel, Jr.<br />

Mr. and Mrs. John R. Sanderson<br />

Ms. Fannette Sawyer<br />

Ms. Joan Schechtman<br />

Mrs. Betty F. Seagrave<br />

Dr. Nadrian C. Seeman<br />

Mr. Norman C. Severo<br />

Drs. C<strong>at</strong>hy Carter & James Shiffner<br />

Mr. and Mrs. A. Warren Smith, Jr.<br />

Ms. Mary Ann Stiefel<br />

Ms. Ruth V. Stockton<br />

Mr. and Mrs. Malcolm Strachan<br />

Dr. Joan M. Sulewski<br />

Ms. Virginia D. Sullivan<br />

Ms. Mimi Swados<br />

Dr. Hiroshi Takita<br />

Mr. and Mrs. John H. Taylor<br />

Mr. and Mrs. Darren Tolsma<br />

U-C Co<strong>at</strong>ings Corpor<strong>at</strong>ion<br />

Mrs. Constance S. Umland<br />

Dr. and Mrs. John M. Wadsworth<br />

Mr. and Mrs. Richard H. Wadsworth<br />

Mr. Louis Wagner<br />

Mr. and Mrs. Edward C. Weeks<br />

Ms. Gretchen White<br />

Mrs. Paul A. Willax<br />

Dr. James A. Williams<br />

Mr. and Mrs. William J. Williamson, Jr.<br />

Mr. Louis P. Willsea<br />

Ms. Sharon Winer<br />

Mr. and Mrs. Herbert R. Winter<br />

WNED-AM/FM<br />

Mr. and Mrs. Frederick A. Wolf<br />

Mr. and Mrs. Albert J. Wright, III<br />

FRIENDS<br />

up to $99<br />

Ms. Deborah Abgott<br />

Mr. and Mrs. Morton Abramson<br />

Aero Club of <strong>Buffalo</strong><br />

Mr. and Mrs. Thomas A. Alberalla<br />

Mr. and Mrs. Keith Alf<br />

Mrs. Rosalyn Algase<br />

Ms. Loma M. Allen<br />

Mr. and Mrs. David Altman<br />

Mrs. Jeanne Archer<br />

Mr. and Mrs. Gary R. Bainbridge<br />

Mr. and Mrs. Bruce Barit<br />

Mr. and Mrs. Irving A. Barrett, Jr.<br />

Mr. and Mrs. Vincent B. Barrett<br />

Mrs. Robert Barton<br />

Mr. and Mrs. Martin B<strong>at</strong>es<br />

Mr. William J. Bauer<br />

Mr. Walter R. Beachy<br />

Mr. Harry Beckerman<br />

Mr. and Mrs. Neil Bedell<br />

Mr. Ronald S. Benson<br />

Mr. Robert F. Berner<br />

Mr. and Mrs. Edward J. Bialek<br />

Mr. Edward Bogom<br />

Mrs. Constance Cody<br />

Ms. Allie Bond Coger<br />

Mr. and Mrs. Edward Bookmiller<br />

Dr. Mary Botsford<br />

Mr. and Mrs. Clinton E. Braine<br />

Mr. and Mrs. John Brennan<br />

Mr. and Mrs. Harvey J. Breverman<br />

Mr. and Mrs. Bruce C. Brock<br />

Ms. Nellie Brown<br />

<strong>Buffalo</strong> Oxygen Service<br />

Mr. Duncan H. Bull<br />

Ms. Margaret Burke<br />

Mr. and Mrs. Dale Burrell<br />

Mr. and Mrs. Richard Byron<br />

Mr. James A. Calandra<br />

Mr. and Mrs. Lawrence S. Carr<br />

Ms. Dorothea R. Carvalho<br />

Mr. Joseph J. Castiglia<br />

Mr. and Mrs. William Castle<br />

Mr. Philip Celniker<br />

Ms. Phyllis Chase<br />

Mr. and Mrs. Gerry Clifford<br />

Dr. and Mrs. Harold Cohen<br />

Mrs. K<strong>at</strong>hryn Cohen<br />

Mr. and Mrs. Robert P. Coleman<br />

Ms. Alice L. Collins<br />

Ms. Connie L. Cordero<br />

Mr. Joseph A. Cozzarin<br />

Mr. Richard G. Crawford<br />

Mrs. Joseph D. Davis<br />

Mr. and Mrs. Roger Davison<br />

Mr. and Mrs. Thomas Dearing<br />

Mr. and Mrs. Dennis Dee<br />

Mrs. Jean Del Bel<br />

Mr. and Mrs. Edward L. Dentinger<br />

Ms. Virginia Deuel<br />

Miss Tinamarie DeVine-Zelasko<br />

Mrs. Carla DiChristina<br />

Mr. and Mrs. John B. Drenning<br />

Mr. Richard W. Eckler<br />

Mr. and Mrs. William A. Elliott<br />

Mr. and Mrs. Maxwell Ellis<br />

Mr. and Mrs. Richard C. Elsaesser<br />

Ms. Marsha A. Fadale<br />

Mr. and Mrs. Marwin L. Feldman<br />

Ms. Priscilla Ferguson<br />

Mr. and Mrs. Jerrold S. Flaschner<br />

Mrs. Helen T. Foley<br />

Ms. Wendy Franke<br />

Ms. Candace A. Frerk<br />

Mrs. Loise H. Frey<br />

Mr. and Mrs. Arthur Fuchs<br />

Mr. and Mrs. Kenneth D. Garnjost<br />

Mr. and Mrs. John L. Garrett<br />

Mrs. Charles R. Gibson<br />

Mr. Gerard J. Glowniak<br />

Mr. and Mrs. Michael Golden<br />

Miss Audrey N. Golnick<br />

Miss Ruth C. Graesser<br />

Mr. and Mrs. Michael N. Grasso<br />

Ms. Mary Lou Grauer<br />

Miss Rochelle A. Gray<br />

Mrs. Clare Grellick<br />

Ms. Rochelle A Grey<br />

Mr. and Mrs. Donald Griffin<br />

Dr. and Mrs. Andrew Gulick, Ph.D.<br />

Mr. and Mrs. Arthur E. Gundlach<br />

Mr. and Mrs. John A. Hahn<br />

Mr. Paul A. Hahnel<br />

Reverend and Mrs. James D. Hakes<br />

Mr. and Mrs. Dean R. Hall<br />

Mrs. Edythe T. Harris<br />

Mr. and Mrs. Charles E. Harter<br />

Mr. and Mrs. Alden Harwood<br />

Dr. and Mrs. Herbert A. <strong>Hauptman</strong><br />

Mr. and Mrs. A. Allan Hayes<br />

Mrs. Sheila M. Hess<br />

Mr. William B. Hill<br />

Mr. and Mrs. Nelson Himmelfarb<br />

Mr. and Mrs. Robert J. Hoag<br />

Ms. Lorraine A. Hollister-Colby<br />

Mr. and Mrs. Arthur M Holtzman<br />

Mr. and Mrs. James S. Howell<br />

Mr. and Mrs. Richard S. Howell<br />

Dr. and Mrs. Richard A. Hubbard, II<br />

Mrs. C. Stuart Hunt<br />

Mr. and Mrs. Howard Hutton<br />

Dr. and Mrs. Edward Hyman<br />

Ms. Sharon Interdon<strong>at</strong>o<br />

Mr. and Mrs. William G. Irr<br />

Mr. and Mrs. P<strong>at</strong>rick R. Janiga<br />

Mr. Daniel R. Jesser<br />

Mr. and Mrs. Walter H. Johansson<br />

Mr. and Mrs. James Johnson<br />

Mrs. Margaret J. Kaiser<br />

Mrs. Adolph Kastelowitz<br />

Ms. Laurie Elliott Krajna<br />

Mr. Courtland R. LaVallee<br />

Mrs. K<strong>at</strong>hleen A. LaVictor<br />

Mrs. Aljean G. Leer<br />

Mr. Douglas J. Levy<br />

Dr. and Mrs. Harold J. Levy<br />

Dr. and Mrs. Stuart W. Maisel<br />

Ms. Irene Majchrzak<br />

Mrs. Lois Malek<br />

Mr. Stephen Manes<br />

Ms. Barbara Markel<br />

Dr. and Mrs. Paul V. Marrone<br />

Mrs. Sarah G. Metzger<br />

Dr. and Mrs. Enrico Mihich<br />

Zachary J. Miknis<br />

Mr. and Mrs. Nelson T Montgomery, II<br />

Ms. Elizabeth G Naramore<br />

Mr. and Mrs. David R. Newcomb<br />

Reverend Mary Jane Nichols<br />

Mr. and Mrs. Nicholas Nickson<br />

Mr. William E. Nitterauer<br />

Ms. Winona Northup<br />

Ms. Lynn M. Nowakowski<br />

Mr. and Mrs. James P. O'Brien<br />

Mr. and Mrs. David M. Parish<br />

Dr. Edwin V. P<strong>at</strong>ricola<br />

Mr. William J. Paxson<br />

Mr. and Mrs. David M. Pecynski<br />

Mr. and Mrs. Stuart Phelps<br />

Ms. Renee B. Piazza<br />

Mr. and Mrs. Richard M. Pirson<br />

Mr. and Mrs. Harvey Podolsky<br />

Mr. and Mrs. Louis Pozarny<br />

Mr. and Mrs. Edwin Presant<br />

Mr. and Mrs. Raymond A. Puleo<br />

Ms. Alice M. Raymond<br />

Leigh S. & Teresa B. Raymond<br />

Mrs. Barbara Rex<br />

Mr. and Mrs. Richard G. Riebling<br />

Mr. and Mrs. C. Thomas Rock<br />

Mr. Benjamin Rodwin<br />

Dr. Charlotte D. Roederer<br />

Mr. and Mrs. William B. Sabey<br />

Mr. and Mrs. Al Saia<br />

Mrs. Mildred S. Sanes<br />

Mr. James Scanzaroli<br />

Ms. Ida Schaer<br />

Mr. and Mrs. Richard J. Schanley<br />

Dr. and Mrs. Ray G. Schiferle<br />

Mr. Walter R. Schoenfeld<br />

Miss Irma Schultz<br />

Mr. and Mrs. Joseph G. Scully<br />

Mr. and Mrs. Arthur L. Selover<br />

Mr. and Mrs. Gust D. Servis<br />

Mr. Eugene M. Setel<br />

Dr. Russell N. Shefrin<br />

Mr. and Mrs. Mark L. Sieracki<br />

Mr. and Mrs. Walter S. Sikora<br />

Ms. Jackie Simon<br />

Ms. Mary B. Sippel<br />

Mr. and Mrs. Alan C. Smith<br />

Ms. Clarice W. Snitzer<br />

Mrs. Sylvia Sommerfield<br />

Ms. Geraldine Sonnesso<br />

Mr. and Mrs. Clarence E. Spitzer, Jr.<br />

Mr. and Mrs. Gerald R. Stafford<br />

Mr. and Mrs. Dean C. St<strong>at</strong>hacos<br />

Mr. and Mrs. Edmund D. Stevens, III<br />

Ms. Doris E. Stone<br />

Ms. Lorraine A. Stone<br />

Mr. and Mrs. Gerald R. Strauss<br />

Ms. Mary S. Swett<br />

Mr. Charles E. Telford<br />

Dr. and Mrs. Richard N. Terry<br />

Col. and Mrs. Henry J. Thayer<br />

Mr. and Mrs. Wm. Dennis Toole<br />

Ms. Melda Tugac<br />

Mr. James J. Tyrpak<br />

Valley View Nurseries, Inc.<br />

Mr. and Mrs. John A. Vogel<br />

Mrs. Laura M. Walfrand<br />

Dr. and Mrs. James Warde<br />

Dr. Charles M. Weeks<br />

Mr. Raymond Weil<br />

Ms. Marie L. Weisbecker<br />

Ms. Linda Wells Davey<br />

Dr. and Mrs. Robert M. Werner<br />

Mr. and Mrs. Philip Weston<br />

Mr. and Mrs. James Wise<br />

Mr. and Mrs. Frederick S. Wood<br />

Mr. and Mrs. Martin S. Wright<br />

Ms. Nancy J. Wright<br />

Mr. Joseph J. Yarborough


RECENT PUBLICATIONS<br />

• Brucz K, Miknis ZJ, Schultz LW, Umland TC. Expression, purific<strong>at</strong>ion and characteriz<strong>at</strong>ion of recombinant severe acute respir<strong>at</strong>ory syndrome<br />

coronavirus non-structural protein 1. Protein Expr Purif. <strong>2006</strong> Nov 14; [Epub ahead of print]<br />

• Cody V, Davis PJ, Davis FB. Molecular modeling of the thyroid hormone interactions with alphavbeta3 integrin. Steroids. <strong>2006</strong> Dec 11;<br />

[Epub ahead of print]<br />

• Cody, V. (2005). Thyroid Hormone Structure-Function Rel<strong>at</strong>ionships. In Werner and Ingbar's The Thyroid: A Fundamental and Clinical Text,<br />

9th edition, Braverman, L. E. & Utiger, R. D. (eds), Lippincott Williams & Wilkins Publishers, Philadel phia, pp. 151-157.<br />

• Cody V, Pace J, Chisum K, Rosowsky A. New insights into DHFR interactions: analysis of Pneumocystis carinii and mouse DHFR complexes<br />

with NADPH and two highly potent 5-(omega-carboxy(alkyloxy) trimethoprim deriv<strong>at</strong>ives reveals conform<strong>at</strong>ional correl<strong>at</strong>ions with activity and<br />

novel parallel ring stacking interactions. Proteins. <strong>2006</strong> Dec1;65(4):959-69.<br />

• Bosch J, Robien MA, Mehlin C, Boni E, Riechers A, Buckner FS, Van Voorhis WC, Myler PJ, Worthey EA, DeTitta G, Luft JR, Lauricella A,<br />

Gulde S, Anderson LA, Kalyuzhniy O, Neely HM, Ross J, Earnest TN, Soltis M, Schoenfeld L, Zucker F, Merritt EA, Fan E, Verlinde CL, Hol WG.<br />

Using fragment cocktail crystallography to assist inhibitor design of Trypanosoma brucei nucleoside 2-deoxyribosyltransferase. J Med Chem.<br />

<strong>2006</strong> Oct 5;49(20):5939-46.<br />

• Ericsson UB, Hallberg BM, DeTitta GT, Dekker N, Nordlund P. Thermofluor-based high-throughput stability optimiz<strong>at</strong>ion of proteins for<br />

structural studies. Anal Biochem. <strong>2006</strong> Oct 15;357(2):289-98<br />

• Immormino RM, Kang Y, Chiosis G, Gewirth DT. Structural and quantum chemical studies of 8-aryl-sulfanyl adenine class Hsp90 inhibitors.<br />

J Med Chem. <strong>2006</strong> Aug 10;49(16):4953-60.<br />

• Xu H, <strong>Hauptman</strong> HA. Recent advances in direct phasing methods for heavy-<strong>at</strong>om substructure determin<strong>at</strong>ion. Acta Crystallogr D Biol<br />

Crystallogr. <strong>2006</strong> Aug;62(Pt 8):897-900.<br />

• Pletnev VZ, Thomas JL, Rhaney FL, Holt LS, Scaccia LA, Umland TC and Duax WL. R<strong>at</strong>ional Proteomics V: Structure-based mutagenesis has<br />

revealed key residues responsible for substr<strong>at</strong>e recognition and c<strong>at</strong>alysis by the dehydrogenase and isomerase activities in human 3betahydroxysteroid<br />

dehydrogenase/isomerase type 1. J. Steroid.Biochem Mol Biol. <strong>2006</strong> Sep; 101(1): 50-60.<br />

• Williams AH, Immormino RM, Gewirth DT, Raetz CR. Structure of UDP-N-acetylglucosamine acyltransferase with a bound antibacterial<br />

pentadecapeptide. Proc N<strong>at</strong>l Acad Sci U S A. <strong>2006</strong> Jul 18;103(29):10877-82.<br />

• Sundlov JA, Garringer JA, Carney JM, Reger AS, Drake EJ, Duax WL, Gulick AM. Determin<strong>at</strong>ion of the crystal structure of EntA, a 2,3dihydro-2,3-dihydroxybenzoic<br />

acid dehydrogenase from Escherichia coli. Acta Crystallogr D Biol Crystallogr. <strong>2006</strong> Jul;62(Pt 7):734-40.<br />

• Snell EH, van der Woerd MJ, Damon M, Judge RA, Myles DA, Meilleur F. Optimizing crystal volume for neutron diffraction: D: -xylose<br />

isomerase. Eur Biophys J. <strong>2006</strong> May 25.<br />

• Holmes MA, Buckner FS, Van Voorhis WC, Verlinde CL, Mehlin C, Boni E, DeTitta G, Luft J, Lauricella A, Anderson L, Kalyuzhniy O, Zucker F,<br />

Schoenfeld LW, Earnest TN, Hol WG, Merritt EA. Structure of ribose 5-phosph<strong>at</strong>e isomerase from Plasmodium falciparum. Acta Crystallograph<br />

Sect F Struct Biol Cryst Commun. <strong>2006</strong> May 1;62(Pt 5):427-31.<br />

• He H, Z<strong>at</strong>orska D, Kim J, Aguirre J, Llauger L, She Y, Wu N, Immormino RM, Gewirth DT, Chiosis G. Identific<strong>at</strong>ion of potent w<strong>at</strong>er soluble<br />

purine-scaffold inhibitors of the he<strong>at</strong> shock protein 90. J Med Chem. <strong>2006</strong> Jan 12;49(1):381-90.<br />

• Meilleur F, Snell EH, van der Woerd MJ, Judge RA, Myles DA. A quasi-Laue neutron crystallographic study of D-xylose isomerase. Eur<br />

Biophys J. <strong>2006</strong> May 4.<br />

• Drake EJ, Nicolai DA, Gulick AM. Structure of the EntB multidomain nonribosomal peptide synthetase and functional analysis of its interaction<br />

with the EntE adenyl<strong>at</strong>ion domain. Chem Biol. <strong>2006</strong> Apr;13(4):409-19.<br />

• Holmes MA, Buckner FS, Van Voorhis WC, Mehlin C, Boni E, Earnest TN, DeTitta G, Luft J, Lauricella A, Anderson L, Kalyuzhniy O, Zucker F,<br />

Schoenfeld LW, Hol WG, Merritt EA. Structure of the conserved hypothetical protein MAL13P1.257 from Plasmodium falciparum. Acta<br />

Crystallograph Sect F Struct Biol Cryst Commun. <strong>2006</strong> Mar 1;62(Pt 3):180-5.<br />

• Arakaki T, Le Trong I, Phizicky E, Quartley E, DeTitta G, Luft J, Lauricella A, Anderson L, Kalyuzhniy O, Worthey E, Myler PJ, Kim D, Baker D,<br />

Hol WG, Merritt EA. Structure of Lmaj006129AAA, a hypothetical protein from Leishmania major. Acta Crystallograph Sect F Struct Biol<br />

Cryst Commun. <strong>2006</strong> Mar 1;62(Pt 3):175-9.<br />

• Robien MA, Bosch J, Buckner FS, Van Voorhis WC, Worthey EA, Myler P, Mehlin C, Boni EE, Kalyuzhniy O, Anderson L, Lauricella A, Gulde<br />

S, Luft JR, DeTitta G, Caruthers JM, Hodgson KO, Soltis M, Zucker F, Verlinde CL, Merritt EA, Schoenfeld LW, Hol WG. Crystal structure of<br />

glyceraldehyde-3-phosph<strong>at</strong>e dehydrogenase from Plasmodium falciparum <strong>at</strong> 2.25 A resolution reveals intriguing extra electron density in the<br />

active site. Proteins. <strong>2006</strong> Mar 15;62(3):570-7.<br />

• Caruthers J, Bosch J, Buckner F, Van Voorhis W, Myler P, Worthey E, Mehlin C, Boni E, DeTitta G, Luft J, Lauricella A, Kalyuzhniy O, Anderson<br />

L, Zucker F, Soltis M, Hol WG. Structure of a ribulose 5-phosph<strong>at</strong>e 3-epimerase from Plasmodium falciparum. Proteins. <strong>2006</strong> Feb<br />

1;62(2):338-42.

Hooray! Your file is uploaded and ready to be published.

Saved successfully!

Ooh no, something went wrong!