Summer Session I, 2006, Dr. Lukas Buehler Syllabus - Structural ...

Summer Session I, 2006, Dr. Lukas Buehler
Syllabus - Structural Biochemistry BIBC 100
MTWR 2 – 3:20 PM, Solis 104
Instructor: Dr. Lukas Buehler
Office at York Hall 4070A (Th 12-1PM organizational only)
Instructional Office Hours at Solis 111 MTh 4-4:50PM
Week Day Lecture topics Reading * Comments
1 M 7/3 Introduction 1
T 7/4 --- --- Holiday
W 7/5 Aqueous solutions 2, 9
R 7/6 Amino acids 4
2 M 7/10 Protein secondary structure 5
Tu 7/11 Protein structure 6
W 7/12 DNA structure 3, 23
R 7/13 DNA binding protein, stability 23
3 M 7/17 RNA structure 26, 23 Midterm Exam (25%)
T 7/18 Polysaccharides 8
W 7/19 Cell membranes 9
R 7/20 Serine proteases (kinetics) 11, 12
4 M 7/24 Hemoglobin (binding) 7 Midterm Exam (25%)
T 7/25 Metallo-proteins 11, 15
W 7/26 Membrane proteins 9, 10
R 7/28 Protein motion / Protein folding 6
5 M 7/31 Molecular motors 28, 17
T 8/1 Cell surface receptors 21, 9, 8
W 8/2 Immune system receptors 28
R 8/3 HIV and drug design 12, 9
S 8/5 FINAL 11:30am to 2:30pm Not cumulative (50%)
� From Voet et al., Fundamentals in Biochemistry, 2 nd edition, 2005
� Many times only parts of a book chapter are covered; please refer to lecture notes,
slides, and reader to narrow your reading to appropriate content.
The class outline is subject to changes announced during class and posted on the class web
page at: http://www.biology.ucsd.edu/classes/bibc100.SU06.1/
TA Sections
Section Day Time Location TA
A02 M 10:00a - 10:50a HSS 1128A Shannon
A03 Tu 12:00p - 12:50p Center 207 Shannon
A04 Tu 4:00p - 4:50p Center 201 Ravi
A01 W 11:00a - 12:50p Center 205 Katharine
A05 W 4:00p - 4:50p Center 205 Ravi

Text Books
Structural Biochemistry, 2nd
(class reader)
by Lukas K. Buehler
J.Wiley & Sons
Policies regarding exams and regrading
Regrading
Summer Session I, 2006, Dr. Lukas Buehler
Fundamentals of Biochemistry, 2nd
by Voet, Voet and Pratt
J.Wiley & Sons, 2005
Regrades for midterms will be allowed and have to be submitted no later than one week from the
time you receive the graded exams. It is the responsibility of TAs grading a particular problem to
make corrections or adjustments. You can submit a written request for more than one problem.
Those requests will be regraded during a regrading session after the one week period allotted to
submit a request.
Make up exams
Midterms are held during class time. Makeup exams are available for emergency reasons and
conflicts with other assignments for which students have no control over the timing. For conflicts
regarding the final exam and having more than two (=3) final exams within a 24-hour period, you
need to contact your college administration to request make up exams. You should do this during
the first week of class and as soon as you are aware of such clustering. There are no makeup
finals if you (or some relatives) make travel arrangements before the end of the scheduled final
exam.
Cheating
To avoid cheating problems, please write in pen and not pencil. If you make changes, mark them
clearly (cross out) and do not erase and write over other words. A small number of exams will be
photo copied (after grading and before students receive them) and compared with the submitted
regrade request. Photocopies are done randomly and are not a systematic approach nor are they
targeting any students in particular. Cheating will be reported to the Dean of your college.