Lynette Masters Neuroradiologist

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• Hemodynamic– Response time of brain activity to the given stimulusand/or cessation of activation• Duration of Activation– Stimulated pain response can linger– Subtle activation needs longer duration periods• Emotional response– Subject response window• applicable for fMRI where choices are presented
PAIN INVESTIGATIONS• Processing of pain– Induced sensory stimulation• Heat• Subcutaneous superficial and deep injections– Chronic pain pre and post therapeuticinterventions• Comparison of stimulation of the painful limbversus non painful limb– Phantom pain in amputees– Does emotional pain cause physical pain?
Page 1 and 2: Lynette MastersNeuroradiologist
Page 3 and 4: • Lateral pain system(sensory-dis
Page 5 and 6: • High resolutionstructural imagi
Page 7 and 8: • Functional MRI (fMRI)• Diffus
Page 9 and 10: “BOLD” IMAGING• Microvascular
Page 11 and 12: “BOLD” IMAGINGRESTACTIVATION100
Page 13 and 14: Right hand tapping
Page 18 and 19: PAIN INVESTIGATIONS• Pain Relief-
Page 20 and 21: • Chronic Pain- Difficult because
Page 23 and 24: • Intra & interhemispheric cortic
Page 25 and 26: MacIver et al, Brain, 2008
Page 27 and 28: Moulton et al, PLoS ONE, 2008
Page 29 and 30: • PET measures cerebral blood flo
Page 31 and 32: • The majority of clinical brain
Page 33: PEAK NAMING
Page 36 and 37: DIFFUSION TENSORIMAGING (DTI)• MR
Page 38 and 39: COMBINED FA & DIRECTIONALMAPS• co
Page 40 and 41: cingulumcorpus callosum corticospin
Page 43: • Tailored diagnosis +/- evaluati

Lynette Masters Neuroradiologist

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