Lynette Masters Neuroradiologist

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DIFFUSION TENSORIMAGING (DTI)• MRI can detect the random (thermal)motion of water molecules in the directionof an applied gradient= diffusion• diffusion in white matter is anisotropic iedirectionally dependent• the direction of maximal diffusivitycorresponds with white matter tractorientation
• The degree of anisotropy and local fibreorientation can be mapped voxel by voxel• fractional anisotropy (FA) ranges from 0(isotropic) to 1 (maximal anisotropy)• the direction of maximal diffusivity can bemapped, with colour brightness modulatedby the FA
Page 1 and 2: Lynette MastersNeuroradiologist
Page 3 and 4: • Lateral pain system(sensory-dis
Page 5 and 6: • High resolutionstructural imagi
Page 7 and 8: • Functional MRI (fMRI)• Diffus
Page 9 and 10: “BOLD” IMAGING• Microvascular
Page 11 and 12: “BOLD” IMAGINGRESTACTIVATION100
Page 13 and 14: Right hand tapping
Page 16 and 17: • Hemodynamic- Response time of b
Page 18 and 19: PAIN INVESTIGATIONS• Pain Relief-
Page 20 and 21: • Chronic Pain- Difficult because
Page 23 and 24: • Intra & interhemispheric cortic
Page 25 and 26: MacIver et al, Brain, 2008
Page 27 and 28: Moulton et al, PLoS ONE, 2008
Page 29 and 30: • PET measures cerebral blood flo
Page 31 and 32: • The majority of clinical brain
Page 33: PEAK NAMING
Page 38 and 39: COMBINED FA & DIRECTIONALMAPS• co
Page 40 and 41: cingulumcorpus callosum corticospin
Page 43: • Tailored diagnosis +/- evaluati

Lynette Masters Neuroradiologist

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