FITC Anti-Rabies Monoclonal Globulin - Fujirebio Diagnostics, Inc.

IFDIFUJIREBIODiagnostics, Inc.O RF DI GI N A LA N TI B O DI E SFITC Anti-Rabies Monocolonal GlobulinFITC ANTI-RABIES MONOCLONAL GLOBULINFOR DETECTION OF RABIES IN BRAINS AND SUBMAXILLARY GLANDSThe Fujirebio Diagnostics, Inc. (FDI) FITC Anti-Rabies Monoclonal Globulin utilizes a directfluorescent antibody procedure for the in vitro detection of rabies in brains and submaxillaryglands. The product is for in vitro diagnostic use.FITC Anti-Rabies Monoclonal GlobulinFDI-066 01/05Proven Quality and ConsistencyThe FDI rabies assay has been used for nearly 20 years, proving its reliability andconsistent performance in the lab. The antibody titer is QC tested and approved bythe Center for Disease Control (CDC) for every lot produced.Widely Used Assay, Reliable Test ProcedureThe monoclonal antibodies (Isotype IgG2a) utilized in our conjugate allow specificand uniform staining with reduced background interference. The fluorescent antibodyassay is one of the most widely used techniques for the diagnosis of rabies. Theprocedure uses dye labeled antibodies that are applied to tissue suspected of beinginfected with Rabies. The antibodies bind to the rabies antigen causing a reaction,which will emit light under a fluorescence microscope.Broad Range of Viruses DetectedThe FITC Anti-Rabies Monoclonal Globulin detects all rabies and lyssaviruses testedto date:VirusesFluorescence Staining of TissueGroup Strains with FDI FITC Anti-Rabies Monoclonal GlobulinRabies Street and Fixed Strains +Rabies-related Duvenhage +Lagos Bat +Mokola +Part Number Description Kit800-092 FITC Anti-Rabies 1x 5.0 mL lyophilized vialMonoclonal GlobulinFujirebio Diagnostics201 Great Valley ParkwayMalvern, PA 19355610.240.3800610.240.3825 faxwww.fdi.comL E A D E R S H I P D E P E N D A B I L I T Y I N N O V A T I O N

References:1. The World Health Organization, 1966. Laboratory Techniques in Rabies, Monograph SeriesNo. 23, Second edition.2. The World Health Organization, 1966. WHO Expert Committee on Rabies. Technical ReportSeries No. 312 Fifth edition.3. McQueen, J.L., Lewis, A.L., and Schneldei, N.J., 1960. Rabies Diagnosis by FluorescentAntibody. Its Evaluation in a Public Health Laboratory. Amer J. Publ. Hlth. 50:1743–1752.4. Wiktor, T.J., and Koprowski, H. 1978. Monoclonal Antibodies Against Rabies VirusProduced by Somatic Cell Hybridization: Detection of Antigenic Variants. Proc. Natl. Acad. Sci.,U.S.A. 75:39385. Wiktor, T.J., Flamand, A., and Koprowski, H. 1980. Use of Monoclonal Antibodies In Diagnosisof Rabies Virus Infection and Differentiating of Rabies and Rabies-Related Viruses.J. Virol. Methods. 1:1–10.6. Letter on file at Centocor from George M. Baer, D.V.M., Centers for Disease Control,Lawrenceville Facility. April 20, 1987.Additional Information:U.S. Centers for Disease Controland PreventionMail Stop A-261600 Clifton Rd., NEAtlanta, GA 303331.888.232.3228www.cdc.gov/ncidod/dvrd/rabies/World Health OrganizationAvenue Appia 201211 Geneva 27Switzerland(+00 41 22) 791 21 11www.who.intU.S. Food and Drug Administration5600 Fishers LanceRockville, MD 208571.800.532.4440www.fda.govWHO Collaborating Centrefor Rabies Sureveillance & Researchat the Federal Research Centrefor Virus Disease of AnimalsPostfach (P.O. Box) 1149D-72001 TubingenFederal Republic of Germany+49 7071 967-210www.who-rabies-bulletin.orgNote: FDI is not responsible for the content or accuracy of information on these websites.FUJIREBIO DIAGNOSTICS SETS THE STANDARD FOR EXCELLENCEFor over 20 years, Fujirebio Diagnostics, Inc. (FDI) has been the trusted source of innovativesolutions in oncology diagnostics. At the heart of FDI’s products are the original Centocorantibodies, forming the base of a product line long recognized around the globe for leadershipand dependability. FDI’s extensive menu of diagnostic products set the standard for excellence:Supported by thousands of peer-reviewed articlesEndorsed by prestigious academic institutions and medical centersProven manufacturing process and ISO 9001 certified quality systemDistributed worldwide by leading healthcare organizationsFor more information, call +1.610.240.3800 or visit www.fdi.comFujirebio Diagnostics201 Great Valley ParkwayMalvern, PA 19355610.240.3800610.240.3825 faxwww.fdi.comL E A D E R S H I P D E P E N D A B I L I T Y I N N O V A T I O N